A clinico-pathological study of bilharziasis in sheep

Six healthy sheep were artificially infested through skin exposure with graded doses of cercariae of Schistosoma mattheei Veglia & LeRoux, 1929. By means of laboratory tests the development of lesions due to the disease could be monitored at weekly intervals, so as to shed light on its pathogenesis. In spite of lowering of the albumin fraction the total serum protein tended to rise, mainly as the result of an increase of beta and gamma globulin concentrations. Bromsulphalein retention was increased in the more acute cases due to portal venous tree obstruction but transaminase activity and bilirubin concentration rose only occasionally and transiently, indicating minimal and passing hepatocellular damage. Anaemia developed, normocytic in character, indicating the effect of simple blood loss. Leucocyte counts were not significantly affected but occasional rises of eosinophile percentage indicated transient episodes of sensitivity. Acid-base disturbances were absent and some loss of sodium and potassium through the bowel wall was demonstrated. Renal and mineral metabolism were not affected.The journals have been scanned in colour with a HP 5590 scanner; 600 dpi. Adobe Acrobat v.11 was used to OCR the text and also for the merging and conversion to the final presentation PDF-format.

Changes in the electrophoretic pattern of sera of dogs suffering from various diseases

The sera of dogs suffering from three diseases commonly encountered in South Africa, viz. babesiosis, rickettsiosis and distemper, have been examined electrophoretically and compared with normal sera. Diagrams of the electrophoretic patterns are given with a description of changes found in them. These changes are discussed in the light of the present knowledge of the diseases as they affect the body organs. The potential value of electrophoresis in the differential diagnosis of these diseases is discussed, and it is concluded that the available information indicates a degree of specificity which could prove useful for this purpose.The articles have been scanned in colour with a HP Scanjet 5590; 300dpi. Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format

Gamma-glutamyl transpeptidase activity in sheep serum : normal values and an evaluation of its potential for detecting liver involvement in experimental lupinosis

A brief survey of the literature on gamma-glutamyl transpeptidase (ƴ-GT) activity is included in this study. The levels of activity in the serum of normal Merino sheep (13, 6- 32, 4 mI.U./ml) were ascertained as a preliminary to following the activity through the entire course of experimentally induced ovine lupinosis, a hepatotoxicosis caused by Phomopsis leptostromiformis (Kühn) Bubák. The response of the serum level of ƴ-GT activity to the course of the disease was compared with that of glutamate oxaloacetic transaminase (GOT) and 2 liver function tests for the purpose of assessing its potential application in the study of this mycotoxicosis. Because the levels of activity of ƴ-GT were more valuable for the early diagnosis of low grade acute intoxication and the detection of chronic liver involvement while those of GOT gave better information on the development of severe acute hepato-cellular damage, these 2 enzymes, considered together, were found to give the best information on the course of the toxicosis. The changes in ƴ-GT activity during various stages of intoxication were also related to the histopathological lesions in the liver.The articles have been scanned in colour with a HP Scanjet 5590; 300dpi. Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format

Skin grafting in surgery for carcinoma of the breast

No Abstrac