KRISTALNE STRUKTURE (2-(PIRIDIN-2-IL)-1H-INDOL- 3-IL)(3,4,5-TRIMETOKSIFENIL)-METANONA (HL) I NJEGOVIH KOMPLEKSA SA Cu(II) I Pd(II)

Novel Cu(II) and Pd(II) complexes with 2-(2’-pyridyl)-indole ligand HL, modified with 3,4,5-trimethoxybenzoyl group, were synthesized with the aim of getting biologically active transition metal complexes. The complexes were synthesized by the reaction of HL with CuCl2·2H2O and [PdCl2(CH3CN)2]. Single crystals of HL and complexes [Cu2L2Cl2(DMSO)2] and [PdL(HL)Cl] were obtained and their structures were determined by X-ray diffraction analysis. Cu(II) complex is a centrosymmetric dimer with squarepyramidal geometry around both metal centers, while Pd(II) complex has square-planar geometry. Molecular structures of HL and complexes are given in Fig. 1. Crystal packings of HL and its Pd(II) and Cu(II) complexes are based on hydrogen bonds and π–π stacking interactions. The main crystallographic data: HL, C23H20N2O4, Mr = 388.41, orthorhombic system, space group Pbca, a = 12.861(5), b = 16.810(5), c = 18.764(5) Å, V = 4057(2) Å3, Z = 8, ρ = 1.272 g cm–3, refinement on F2 (270 parameters) yielded R1 = 0.0681, wR2 = 0.1092, S = 1.040 for all data, and R1 = 0.0458 for 2629 observed reflections with I ≥ 2σ(I). [Cu2L2Cl2(DMSO)2], C25H25ClCuN2O5S, Mr = 564.52, triclinic system, space group P –1, a = 7.7503(4), b = 12.0523(7), c = 13.6355(8) Å, α = 83.347(5), β = 81.711(5), γ = 89.180(4)°, V = 1251.88(12) Å3, Z = 2, ρ = 1.498 g cm– 3, refinement on F2 (338 parameters) yielded R1 = 0.0485, wR2 = 0.0934, S = 1.053 for all data, and R1 = 0.0402 for 3839 for observed reflections with I ≥ 2σ(I). [PdL(HL)Cl], C46H39ClN4O8Pd, Mr = 917.66, monoclinic system, space group P21/n, a = 11.8254(2), b = 14.7137(2), c = 23.3483(4) Å, β = 104.498(2)°, V = 3933.13(11) Å3, Z = 4, ρ = 1.550 g cm–3, refinement on F2 (567 parameters) yielded R1 = 0.0396, wR2 = 0.0818, S = 1.051 for all data, and R1 = 0.0307 for 5884 observed reflections with I ≥ 2σ(I).Novi kompleksi Cu(II) i Pd(II) sa 2-(2’-piridil)-indolskim ligandom HL, modifikovanim dodatkom 3,4,5-trimetoksibenzoil grupe, sintetisani su sa ciljem dobijanja biološki aktivnih kompleksa prelaznih metala. Kompleksi su sintetisani reakcijom HL sa CuCl2·2H2O, odnosno [PdCl2(CH3CN)2]. HL i kompleksi [Cu2L2Cl2(DMSO)2] i [PdL(HL)Cl] su dobijeni u vidu monokristala i njihova struktura je rešena rendgenskom strukturnom analizom. Kompleks Cu(II) je centrosimetrični dimer sa kvadratno-piramidalnim okruženjem oko oba metalna centra, dok je kompleks Pd(II) kvadratno- planarne geometrije. Molekulske strukture liganda HL i kompleksa prikazane su na Slici 1. Kristalno pakovanje HL i njegovih kompleksa je zasnovano na vodoničnim vezama i π–π steking interakcijama. Osnovni kristalografski podaci: HL, C23H20N2O4, Mr = 388,41, ortorombični sistem, prostorna grupa Pbca, a = 12,861(5), b = 16,810(5), c = 18,764(5) Å, V = 4057(2) Å3, Z = 8, ρ = 1,272 g cm–3, utačnjavanje sa F2 (270 parametra) dalo je R1 = 0,0681, wR2 = 0,1092, S = 1,040 za sve podatke i R1 = 0,0458 za 2629 refleksija sa I ≥ 2σ(I). [Cu2L2Cl2(DMSO)2], C25H25ClCuN2O5S, Mr = 564,52, triklinični sistem, prostorna grupa P –1, a = 7,7503(4), b = 12,0523(7), c = 13,6355(8) Å, α = 83,347(5), β = 81,711(5), γ = 89,180(4)°, V = 1251,88(12) Å3, Z = 2, ρ = 1,498 g cm–3, utačnjavanje sa F2 (338 parametra) dalo je R1 = 0,0485, wR2 = 0,0934, S = 1,053 za sve podatke i R1 = 0,0402 za 3839 refleksija sa I ≥ 2σ(I). [PdL(HL)Cl], C46H39ClN4O8Pd, Mr = 917,66, monoklinični sistem, prostorna grupa P21/n, a = 11,8254(2), b = 14,7137(2), c = 23,3483(4) Å, β = 104,498(2)°, V = 3933,13(11) Å3, Z = 4, ρ = 1,550 g cm–3, utačnjavanje sa F2 (567 parametra) dalo je R1 = 0,0396, wR2 = 0,0818, S = 1,051 za sve podatke i R1 = 0,0307 za 5884 refleksija sa I ≥ 2σ(I)

METAL-ORGANSKE UMREŽENE STRUKTURE SREBRA(I) SA POTENCIJALNIM ANTIMIKROBNIM SVOJSTVIMA

Jedan od glavnih svetskih problema u javnom zdravlju predstavlja pojava novih otpornih sojeva mikroba. Stoga je potreba za novim antimikrobnim agesima pravi izazov. Metalorganske umrežene strukture (engl. metal-organic frameworks, MOFs) se mogu smatrati obećavajućim antimikrobnim agensima stoga što njihove neorganske i organske komponente mogu da obezbede platformu za visoku antimikrobnu aktivnost. Tokom proteklih godina, nova jedinjenja srebra, uključujući i nove materijale, su se pokazala kao snažni antimikrobni agensi [1]. Uzimajući ovo u obzir, sintetisana su četiri nova MOF-a srebra(I) sa derivatima tiomorfolina i piperazina (Shema 1) koji su okarakterisani rendgenskom strukturnom analizom. Antimikrobna aktivnost je određena na osam bakterijskih sojeva i tri soja gljivica. Kompleks 4 je pokazao dobru antimikrobnu aktivnost na svim testiranim sojevima mikroorganizama.Resistant microbial strains are continuously emerging which is one of the major worldwide public health concerns. The need for new antimicrobial agents is a real challenge. Metal-organic frameworks (MOFs) can be considered as promising antimicrobial materials because their inorganic and organic components can provide platforms to generate high potent antimicrobial activity. Over recent years, new silver compounds, including new materials, have been proposed as potent antimicrobial agents [1]. Taking this into account, four new silver-based MOFs were synthesized (Scheme 1), using thiomorpholine and piperazine derivatives as ligands, and characterized by X-ray diffraction analysis. The antimicrobial activity was evaluated on eight bacterial and three fungi strains. Complex 4 has good antimicrobial activity on all studied microorganisms

Magnetno-strukturne korelacije kod bakar(II) kompleksa sa hloridnim ligandima u mostu

A considerable amount of work has been carried out aiming at correlating structures of a large variety of chlorido-bridged copper(II) complexes and their magnetic properties. Magnetic properties of such systems depend on the nature of terminal ligands, the coordination geometry around the copper atoms, and structural distortions from an ideal geometry. Copper(II) complexes with the condensation derivative of methyl hydrazinoacetate and 2-acetylpyridine were synthesized and characterized by a single crystal X-ray diffraction. Magnetic properties of both complexes are discussed based on X-ray structures and SQUID measurements. Magnetostructural comparisons to structurally similar copper(II) complexes are provided, and a possible correlation has been established.Obimna istraživanja su izvršena u cilju korelacije strukture i magnetnih svojstava velikog broja različitih bakar(II) kompleksa sa hloridnim ligandima u mostu. Magnetna svojstva ovakvih sistema zavise od prirode terminalnih liganada, koordinacione geometrije oko atoma bakra i strukturnih distorzija od idealne geometrije. Sintetisana su dva bakar(II) kompleksa sa kondenzacionim derivatom metilhidrazinoacetata i 2-acetilpiridina koja su okarakterisana metodom difrakcije X-zraka sa monokristala. Diskutovana su magnetna svojstva kompleksa na osnovu rezultata rendgenske strukturne analize i magnetnih merenja merenja SQUID tehnikom. Izvršena su magnetno-strukturna poređenja sa strukturno sličnim bakar(II) kompleksima i uspostavljena je moguća korelacija između strukture i magnetnih svojstava kompleksa

Koordinacioni polimer Ag(I) sa 1,2,4,5-benzentetrakarboksilnom kiselinom i tiomorfolin-4-karbonitrilom

Metal-organic frameworks (MOFs) are regarded as promising materials for applications in catalysis, separation, gas storage and molecular recognition. Here we report the synthesis and characterization of novel silver(I) MOF obtained by the reaction of silver(I) nitrate with 1,2,4,5- benzenetetracarboxylic acid (H4BTEC) and thiomorpholine-4-carbonitrile (tmc). As shown by X-ray difraction analysis, silver(I) centers have distorted tetrahedral geometry with two coordination sites occupied by carboxylic oxygen atoms of two H4BTEC, and the other two by N-atom from nitrile group and S-atom of tmc, respectively. Adjacent silver-carboxylate chains are connected by two tmc ligands into a 2D polymeric structure. Water molecules between these 2D layers are hydrogen bonded to carboxylic groups from adjacent layers and thus expanding the 2D structure into a supramolecular 3D structure. Hydrogen bonds make this structure flexible and suitable for gas absoption. Potential aplication of this coordination polymer as a hydrogen storage material will be the subject of further investigations.Metal-organske umrežene strukture (engl. Metal organic frameworks, MOFs) predstavljaju potencijalno dobre materijale sa primenom u katalizi, odvajanju, skladištenju gasova i molekulskom prepoznavanju. U ovom radu opisana je sinteza i karakterizacija novog MOF-a srebra(I) dobijenog reakcijom srebro(I)-nitrata sa 1,2,4,5-benzentetrakarboksilnom kiselinom (H4BTEC) i tiomorfolin-4-karbonitrilom (tmc). Rendgenska strukturna analiza je pokazala da srebro(I) centri imaju distorgovanu tetraedarsku geometriju, pri čemu dva koordinaciona mesta zauzimaju atomi kiseonika dva molekula H4BTEC, dok su druga dva koordinacina mesta zauzimaju redom N-atom nitrilne grupe i S-atom tmc-a. Susedni srebro-karboksilatni lanci su povezani preko dva tmc liganda u 2D polimernu strukturu. Između 2D slojeva nalaze se molekuli vode koji grade vodonične veze sa karboksilatnim grupama iz susednih slojeva formirajući supramolekulsku 3D strukturu. Vodonične veze čine ovu strukturu fleksibilnom i pogodnom za apsorpciju gasova. Potencijalna primena ovog koordinacionog polimera za skladištenje vodonika će biti predmet daljih istraživanja

Supplementary data for article: Filipović, N. R.; Elshaflu, H.; Grubišić, S.; Jovanović, L. S.; Rodić, M.; Novaković, I.; Malešević, A.; Djordjević, I. S.; Li, H.; Šojić, N.; et al. Co(III) Complexes of (1,3-Selenazol-2-Yl)Hydrazones and Their Sulphur Analogues. Dalton Transactions 2017, 46 (9), 2910–2924. https://doi.org/10.1039/c6dt04785h

Supplementary material for: [https://doi.org/10.1039/c6dt04785h]Related to published version: [http://cherry.chem.bg.ac.rs/handle/123456789/2430

ニホン ジジョウ コース ニオケル プロジェクト ワーク ノ ココロミ : リュウガクセイ ノ タメ ノ セイカツ ハンドブック トクシマ ダイガク エ ヨウコソ ノ サクセイ オ トオシテ

共通教育の「日本事情I」では、グループ学習として効果のあるプロジェクト・ワークを取り上げ、「留学生のための生活ハンドブックー徳島大学へようこそ」を作成した。その作成を通してプロジェクトワークを振り返り、プロジェクトワークとは何か、どのような効果があるかなど考察し、次へと繋げて行きたい

Supplementary data for article: Filipović, N. R.; Elshaflu, H.; Grubišić, S.; Jovanović, L. S.; Rodić, M.; Novaković, I.; Malešević, A.; Djordjević, I. S.; Li, H.; Šojić, N.; et al. Co(III) Complexes of (1,3-Selenazol-2-Yl)Hydrazones and Their Sulphur Analogues. Dalton Transactions 2017, 46 (9), 2910–2924. https://doi.org/10.1039/c6dt04785h

Supplementary material for: [https://doi.org/10.1039/c6dt04785h]Related to published version: [http://cherry.chem.bg.ac.rs/handle/123456789/2430

Trans-border (South-Eastern Serbia/South-Western Bulgaria) correlations of the Jurassic sediments: The Getic and Supra-Getic units

The Getic and Supra-Getic are palaeogeographic units in SE Serbia and SW Bulgaria. Based on the presence (in Eastern) or absence (in Western) of Lower Jurassic marine deposits, the Getic is divided into Eastern and Western. In the Eastern Getic, the Lower Jurassic sedimentation in SE Serbia is represented by the Vidlič Clastites covered by the Lukanja Coal Beds, Lukanja Quartz Sandstones, Lukanja Brachiopods Beds, Lukanja Marlstones, Lukanja Belemnitic-Gryphaean Beds and Lukanja Cephalopod Limestones; in SW Bulgaria, the sedimentation commenced with the Tuden Formation, followed by the Kostina Formation and the Ozirovo Formation with a few members. The Middle Jurassic in SE Serbia commenced with the Senokos Siltstones and Shales and the Gulenovci Beds, while in SW Bulgaria with black shales (the Etropole Formation), followed by marls and clayey limestones of the Bov Formation. The Middle Jurassic sediments are represented in the Western Getic of SE Serbia by the Kurilovo Clastites and the Kurilovo Limestones (synonym to Gumpina Limestones of KRAÜTNER & KRSTIĆ 2003); in the Supra-Getic of SE Serbia they are formed by the Jerma Clastites and Jerma Limestones (synonym of the Gumpina Limestones). In SW Bulgaria the Middle Jurassic sediments are represented by the sandstones of the Gradets Formation and by the bioclastic limestones of the Polaten Formation. During the Callovian (Middle?) started the formation of a carbonate platform with micritic limestones. In SE Serbia, it is Basara Limestones, Vidlič Limestones, Beljanica and Ždrelo Limestones, and in SW Bulgarian, the Belediehan Formation of Callovian-Kimmeridgian p.p. age. Characteristic for the Supra- Getic is the formation of a few grabens with specific sedimentation: the Svetlya Graben (the Zhablyano and Ozirovo Formations) and the Lobosh Formation; the Treklyano Graben (the Dobridol and Sredorek Formations), and out of it - the Methohya and Sredorek Formation. During the Callovian-Kimmeridgian p.p., in the Svetlya Graben was sedimented the Lobosh Formation, horizontally passing into the Javorets and Gintsi Formations. During the latest Kimmeridgian-Tithonian commenced a big facial diversification: on the Getic in SE Serbia sedimented reef or sub-reef limestones (the Crni Vrh and Kučaj Reef Limestones), while in SW Bulgaria, the Slivnitsa Formation. On the Supra-Getic in SE Serbia formed Lužnica Flysch and in SW Bulgaria pre-flysch of the Neshkovtsi Formation and siliciclastic flysch of the Kostel Formation

Trans-border (east Serbia/west Bulgaria) correlation of the morpho-tectonic structures

In the Bulgarian and Serbian geological literatures, many maps, both geological and tectonic, exist showing the structures, but limiting them nationally. There are very few publications correlating the structures from both sides of the border and they preserve the local Bulgarian or Serbian names. Our aim is to create a base for the unification of the names defining the major morpho-tectonic structures: the Moesian Platform, the Miroč - Fore-Balkan Unit, the Poreč-Stara Planina Unit, the Krayna Unit, the Getic - Srednogorie Unit, the Supra Getic - Kraishtide Zone, the Serbo-Macedonian - Thracian Massif and the Vardar Zone, showing their synonyms from the Bulgarian and Serbian sides