Demographic characteristics of 378 infants admitted with bronchiolitis and univariate analysis.

<p>Nominal data expressed as number and per cent of complete data for that factor, missing data excluded. Scale data expressed as group mean and (95% Confidence Interval).† Chi-square (Χ²) comparison with England 2001 census birth to one year old sex data.</p

Results of multivariate analysis including all potential covariates predicting severe bronchiolitis in 378 infants admitted to hospital.

<p>The reference category is: No supplemental oxygen needed. Goodness of fit, Pearson's Χ² = 609 (p = 0.040) and Deviance is not significant (p = 0.999).</p

Results of multivariate analysis; independent variables predicting severe bronchiolitis in 299 RSV positive infants admitted to hospital with bronchiolitis.

<p>The reference category is: No supplemental oxygen needed. Variables included but rejected where the Odds Ratios were not significant in both dependent outcomes included sex, gestation, birth-weight, corrected age on admission, family history of atopy, and deprivation score (IMD 2004). Goodness of fit, Pearson's Χ² = 663 (p<0.001) and Deviance is not significant (p = 0.999).</p

Proportion of infants by deprivation quintile.

<p>Deprivation quintiles (1 least deprived, 5 most deprived); infants recruited to this study with bronchiolitis (black), all Liverpool infants in 2001 census (grey) and all English infants in 2001 census (white).</p

Results of multivariate analysis; independent variables predicting severe bronchiolitis in 378 infants admitted to hospital.

<p>The reference category is: No supplemental oxygen needed. Variables included but rejected where the Odds Ratios were not significant in both dependent outcomes included sex, gestation, birth-weight, corrected age on admission, family history of atopy, and deprivation score (IMD 2004). Goodness of fit, Pearson's Χ² = 726 (p<0.001) and Deviance is not significant (p = 0.999).</p

Predictive values of CATs, CURB-65 and PMEWS scores for predicting severe outcomes in adults (≥16 years, n = 1040).

*<p>Combined measure of severe outcomes (Level 2/3 admission or death).</p

Distribution of CATs, CURB-65 and PMEWS scores according to outcome measures (Level 2/3 admission, mortality, combined measure of severe outcomes) in adults (≥16 years).

*<p>Combined measure of severe outcomes (Level 2/3 admission or death).</p

Multivariable analyses of CAT criteria as independent predictors of outcomes in children (<16 years), forward stepwise regression.

<p>Values are adjusted odds ratios (95% confidence intervals), significant values in bold and p values in italic. Each predictor variable (CAT criterion) in model adjusted for other criteria in the multivariable model remaining following forward stepwise regression (significance level for addition to the model p≤0.05); * criteria excluded from the final model. X Not calculated as this criterion typically directs the outcome (use of supplemental oxygen).</p

The predictive values of CATs, CURB-65 and PMEWS for predicting severe outcomes in adults and children with pandemic influenza.

<p>ROC curves comparing the predictive value of CATs (black solid line), CURB-65 (grey dash line) and PMEWS (black dash line) in relation to Level 2/3 admissions (upper panels), mortality (middle panels) and combined severe outcomes (lower panels) in adults (left panels, age ≥16 years, n = 1040) and children (right panels, age<16 years, n = 480).</p

Distribution of CATs, CURB-65 and PMEWS scores according to outcome measures (Level 2/3 admission, mortality, combined measure of severe outcomes) in children (<16 years).

*<p>Combined measure of severe outcomes (Level 2/3 admission or death).</p