Studies on Antimicrobial Evaluation of Some 1-((1-(1<i>H</i>-Benzo[<i>d</i>]imidazol-2-yl)ethylidene)amino)-6-((arylidene)amino)-2-oxo-4-phenyl-1,2-dihydropyridine-3,5-dicarbonitriles

<div><p></p><p>A new series of 1-((1-(1<i>H</i>-benzo[<i>d</i>]imidazol-2-yl)ethylidene)amino)-6-((arylidene)amino)-2-oxo-4-phenyl-1,2-dihydropyridine-3,5-dicarbonitriles <b>(4a–o)</b> have been synthesized for the development of antimicrobial agents. Newly synthesized compounds were evaluated for their in vitro antibacterial activity against Gram-positive bacteria (<i>Pseudomonas aeruginosa</i>, <i>Streptococcus pyogenes</i>), Gram-negative bacteria (<i>Escherichia coli</i>, <i>Staphylococcus aureus</i>), and antifungal activity (<i>Candida albicans</i>, <i>Aspergillus niger</i>, <i>Aspergillus clavatus</i>). These compounds were characterized by infrared, ¹H NMR, ¹³C NMR, and mass spectra. The synthesized compounds <b>4b, 4e, 4 h,</b> and <b>4k</b> showed potent antimicrobial activity against tested microorganisms.</p></div