283 research outputs found

    Good and Poor Summary Writers' Strategies: The Case of Japanese High School EFL Learners

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    Despite general belief about the importance of summary writing in foreign language education, and in the field of teaching Language for Academic Purposes (LAP) (e.g., Swales, 1981; 2000), it is shown that the development of this skill is one of the most difficult skills for learners (e.g., Brown and Day, 1980; Hirvela & Du, 2013; Shi, 2012). This study is part of a larger project and its main purpose is to open the black box by exploring the relationship between performances of summary writing in English as a Foreign Language (EFL) and the strategies used for summary writing in EFL. A total of 74 Japanese high school EFL learners were asked to write a summary of one-third of approximately 230 word-long English passage and were subsequently asked to respond to the summary strategy inventory adapted partly from Li (2014). The data analysis showed that there was indeed a relationship between the quality of the students' summaries and the frequency of their implemented strategies. In this study, along with the results of in-depth analyses, various implications are offered to EFL education as well as future research studies

    The effect of modifiable healthy practices on higher-level functional capacity decline among Japanese community dwellers

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    This study aimed to clarify the effects of the accumulation of 8 modifiable practices related to health, including smoking, alcohol drinking, physical activity, sleeping hours, body mass index, dietary diversity, ikigai (life worth living), and health checkup status, on higher-level functional capacity decline among Japanese community dwellers. Data were derived from the National Institute for Longevity Sciences - Longitudinal Study of Aging. Subjects comprised 1269 men and women aged 40 to 79 years at baseline (1997–2000) who participated in a follow-up postal survey (2013). Higher-level functional capacity was measured using the Tokyo Metropolitan Institute of Gerontology Index of Competence (total score and 3 subscales: instrumental self-maintenance, intellectual activity, and social role). The odds ratio (OR) and 95% confidence interval (CI) for a decline in higher-level functional capacity in the follow-up study according to the total number of healthy practices were analyzed using the lowest category as a reference. Multivariate adjusted ORs (95% CIs) for the total score of higher-level functional capacity, which declined according to the total number of healthy practices (0–4, 5–6, 7–8 groups) were 1.00 (reference), 0.63 (0.44–0.92), and 0.54 (0.31–0.94). For the score of social role decline, multivariate adjusted ORs (95% CIs) were 1.00 (reference), 0.62 (0.40–0.97), and 0.46 (0.23–0.90), respectively (P for trend = 0.04). Having more modifiable healthy practices, especially in social roles, may protect against a decline in higher-level functional capacity among middle-aged and elderly community dwellers in Japan

    DNA secondary structure is influenced by genetic variation and alters susceptibility to de novo translocation

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    <p>Abstract</p> <p><b>Background</b></p> <p>Cumulative evidence suggests that DNA secondary structures impact DNA replication, transcription and genomic rearrangements. One of the best studied examples is the recurrent constitutional t(11;22) in humans that is mediated by potentially cruciform-forming sequences at the breakpoints, palindromic AT-rich repeats (PATRRs). We previously demonstrated that polymorphisms of PATRR sequences affect the frequency of <it>de novo </it>t(11;22)s in sperm samples from normal healthy males. These studies were designed to determine whether PATRR polymorphisms affect DNA secondary structure, thus leading to variation in translocation frequency.</p> <p><b>Methods</b></p> <p>We studied the potential for DNA cruciform formation for several PATRR11 polymorphic alleles using mobility shift analysis in gel electrophoresis as well as by direct visualization of the DNA by atomic force microscopy. The structural data for various alleles were compared with the frequency of <it>de novo </it>t(11;22)s the allele produced.</p> <p><b>Results</b></p> <p>The data indicate that the propensity for DNA cruciform structure of each polymorphic allele correlates with the frequency of <it>de novo </it>t(11;22)s produced (r = 0.77, <it>P </it>= 0.01).</p> <p><b>Conclusions</b></p> <p>Although indirect, our results strongly suggest that the PATRR adopts unstable cruciform structures during spermatogenesis that act as translocation hotspots in humans.</p

    CD Investigation of Porphyrin-Porphyrin Interaction with Links to Acyclic β-Sheet Peptide Self-Assembled in an Aqueous Media

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    Amphiphilic peptide, Ac-Cys(Por)-Lys-Val-(-Ser-Val-)n-Lys-Val-NH2 (n = 0 or 1, Cys(Por) = side-chain porphyrin-linked Cys), self-assembled to form the β-sheet in buffer solution-2,2,2-trifluoroethanol and showed exciton coupled Cotton effects in the porphyrin region due to the closely ori?ented porphyrin

    Role of Community Health Volunteers Since the 2015 Nepal Earthquakes: A Qualitative Study

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    Objective: Nepal female community health volunteers (FCHVs) were the first available health personnel in communities during the 2015 Nepal earthquakes. This study explored the facilitating factors and barriers of the FCHVs during health emergencies. Methods: In-depth interviews with 24 FCHVs and 4 health managers from 2 districts in Nepal (Gorkha and Sindhupalchowk) were conducted using semi-structured interview guides. The qualitative data were analyzed using thematic analysis methods. Results: FCHVs were the first responders to provide services after the earthquakes and were well accepted by the local communities. Different models of supervision existed, and differences in the workload and remuneration offered to FCHVs were described. A wide range of disaster-related knowledge and skills were required by FCHVs, and lack of prior training was an issue for some respondents. Furthermore, lack of access to adequate medical supplies was a major barrier for FCHVs in the 2015 earthquakes. The 5 identified themes were discussed. Conclusion: Providing regular disaster response training for FCHVs and strong leadership from the public sector with sustained investments will be essential for increasing the capacities of community health workforces to prepare for and reduce the impacts of future health emergencies in resource-poor settings
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