Replica Method for Wide Correlators in Gaussian Orthogonal, Unitary And Symplectic Random Matrix Ensembles

We calculate connected correlators in Gaussian orthogonal, unitary and symplectic random matrix ensembles by the replica method in the 1/N-expansion. We obtain averaged one-point Green's functions up to the next-to-leading order O(1/N) and wide two-level correlators up to the first nontrivial order O(1/N^2) and wide three-level correlators up to the first nontrivial order $O(1/N^4)$ by carefully treating fluctuations in saddle-point evaluation.Comment: LaTeX 21 pages, a new result on wide three-level correlators adde

Higher risk of renal impairment associated with tenofovir use amongst people living with HIV in India: A comparative cohort analysis between Western India and United Kingdom

Background: Data on the renal safety of Tenofovir (TDF) in Low and Middle Income Countries (LMICs) is scarce. We compared development of various forms of renal impairment with use of TDF-containing antiretroviral therapy (ART) between a cohort from the Institute of Infectious Diseases (IID) Pune, Western India and the Royal Free Hospital (RFH) London, UK. Methods: This is a retrospective analysis of change in estimated glomerular filtration rates (eGFRs) at 6, 12 and 24 months post TDF initiation using the Modification of Diet in Renal Disease (MDRD) equation. In people living with Human Immunodeficiency virus (PLHIV) with pre-TDF eGFR > 90 ml/min/1.73 m2 time to development of and factors associated with progression to eGFR < 60 ml/min/1.73 m2 were calculated using standard survival methods. Results: A total of 574 (59% Caucasian) at the RFH, and 708 (100% Indian ethnicity) PLHIV from IID were included. Baseline median eGFR were similar; RFH 102 (IQR 89, 117), IID 100 (82, 119). At 24 months, mean (SD) decline in eGFR was -7(21) at RFH (p  90 ml/min/1.73 m2 PLHIV at IID were more likely to develop an eGFR < 60 ml/min/1.73 m2 (aHR = 7.6 [95% CI 3.4, 17.4] p < 0.0001) and had a faster rate of progression estimated using Kaplan Meier methods. Risk factors included age (per 10 years older: aHR = 2.21 [1.6, 3.0] p < 0.0001) and receiving concomitant ritonavir boosted Protease Inhibitor (PI/r) (aHR = 2.4 [1.2, 4.8] p = 0.01). Conclusions: There is higher frequency of treatment limiting renal impairment events amongst PLHIV receiving TDF in Western India. As TDF scale up progresses, programs need to develop capacity for monitoring and treatment of renal impairment associated with TDF

Principles of International Law Relevant for Consideration in the Design and Implementation of Trade-Related Climate Measures and Policies. Report of an International Legal Expert Group.

The report offers independent guidance for governments and stakeholders by eminent legal experts on principles of international law relevant for consideration in the design and implementation of trade-related climate measures and policies. The report reviews a set of recognized principles of international law that the expert group deems especially relevant for consideration including: Sovereignty; Prevention; Cooperation; Prohibition of Arbitrary & Unjustifiable Discrimination; Sustainable Development, Equity, & CBDR-RC; and Transparency & Consultation. The vision driving this report is that shared understandings on such principles could help foster dialogue and international cooperation on the design and implementation of trade-related climate measures and policies in the context of sustainable development priorities. According to the expert group, trade-related climate measures and policies should be approached as legal hybrids. Their rationale, design, and the debates about them draw from different areas of international law relating to the environment, climate, international trade and general international law. The principles are analysed in a way that presents them as cumulative and simultaneously applicable, in a mutually supportive and coherent manner, giving full effect to all relevant parts of international law, insofar as possible

Livre blanc Une seule santé

L’objectif de ce livre blanc est d’examiner le concept « Une seule santé » (aussi appelé « approche » ou « dimension ») du point de vue du droit international et de la gouvernance mondiale et de contribuer aux discussions relatives à l’intégration de ce concept dans le système juridique international. Ce livre blanc se fonde en grande partie sur des entretiens conduits avec douze experts actifs dans les différents domaines liés à l’approche « Une seule santé »

White Paper on One Health

The purpose of this White Paper is to examine the One Health concept (also called “approach” or “dimension”) from an international law and global governance perspective and to contribute to discussions on the integration of this term into the international legal system. It is largely based on interviews with twelve experts in the various domains related to One Health

Revue des Revues

Gareau Jean-François, Bodeau Pierre, Canal Grégory, De Frouville Olivier, Eisemann Pierre Michel, Guillot Philippe, Henchoz Alain-Denis, Kohen Marcelo G., Mbengue Makana Moïse, Pellet Alain, Renaut Céline. Revue des Revues. In: Annuaire français de droit international, volume 48, 2002. pp. 908-944

Revue des Revues

Gareau Jean-François, Bodeau Pierre, Canal Grégory, De Frouville Olivier, Eisemann Pierre Michel, Guillot Philippe, Henchoz Alain-Denis, Kohen Marcelo G., Mbengue Makana Moïse, Pellet Alain, Renaut Céline. Revue des Revues. In: Annuaire français de droit international, volume 48, 2002. pp. 908-944

Revue des Revues

Gareau Jean-François, Canal Grégory, De Frouville Olivier, Desgagné Richard, Eisemann Pierre Michel, Guillot Philippe, Henchoz Alain-Denis, Kohen Marcelo G., Mbengue Makana Moïse, Nesi Giuseppe, Pellet Alain, Quéguiner Jean-François, Renaut Céline, Tavernier Paul, Villalpando Santiago. Revue des Revues. In: Annuaire français de droit international, volume 47, 2001. pp. 707-769

Revue des Revues

Gareau Jean-François, Canal Grégory, De Frouville Olivier, Desgagné Richard, Eisemann Pierre Michel, Guillot Philippe, Henchoz Alain-Denis, Kohen Marcelo G., Mbengue Makana Moïse, Nesi Giuseppe, Pellet Alain, Quéguiner Jean-François, Renaut Céline, Tavernier Paul, Villalpando Santiago. Revue des Revues. In: Annuaire français de droit international, volume 47, 2001. pp. 707-769