Noise Measurement Setup for Quartz Crystal Microbalance

Quartz crystal microbalance (QCM) is a high sensitive chemical sensor which has found widespread spectrum of applications. There are several mechanisms that are related to fluctuation phenomena. Since the aim of our research is oriented to study the sensitivity and influence of different kind of noises on sensor resolution, we modified an existing method to measure the small frequency fluctuation of QCM. The paper describes our measurement setup, in which a quartz crystal oscillator with coated active layers and a reference quartz oscillator are driven by two oscillator circuits. Each one regulates a frequency of a crystal at the minimum impedance which corresponds to the series resonance. A data-acquisition card triggers on the rise-edges of the output signal and stores these corresponding times on which the instantaneous frequency is estimated by own-written software. In comparison to other measurement setups, our approach can acquire immediate change of QCM frequency, thus, chemical processes can be even described on the basis of high-order statistics. The experiments were provided on quartz crystals with the sorption layer of polypyrrole, which is suitable for the construction of QCM humidity sensors

Rationale for the treatment of children with CCSK in the UMBRELLA SIOP-RTSG 2016 protocol

The International Society of Paediatric Oncology-Renal Tumour Study Group (SIOP-RTSG) has developed a new protocol for the diagnosis, treatment, and follow-up monitoring of childhood renal tumours-the UMBRELLA SIOP-RTSG 2016 protocol (the UMBRELLA protocol). This protocol has been designed to continue international collaboration in the treatment of childhood renal tumours and will be implemented in over 50 different countries. Clear cell sarcoma of the kidney, which is a rare paediatric renal tumour that most commonly occurs in childre

Analysis of railway carriage movement on curved track

W opracowaniu zamieszczono analizę ruchu wagonu kolejowego po zakrzywionym torze. Model komputerowy wykonano w oprogramowaniu Siemens PLM NX, symulację w oprogramowaniu ADAMS. Badania obejmowały wyszczególnienie odcinków toru, poprzez podział na odcinek rozpędzania składu do zadanej prędkości oraz odcinek ruchu na zakręcie. Symulację wykonano z użyciem dwóch modeli, tj. ruchu bez ładunku oraz z pełnym ładunkiem. Wynikiem analizy są wykresy przedstawiające siłę nacisku zestawów kołowych na torowisku oraz siłę nacisku ładunku na drzwi wagonu.The paper focuses on the analysis of movement of a railway carriage on a curved track. The computer model was made in the Siemens PLM Software NX and the simulation process was performed in the ADAMS software. The investigation included the specification of track sections, by dividing the acceleration storage section to a specified speed and distance of movement on the cusp. The simulation was performed using two models: movement without load and when fully loaded. The result of the analysis is shown in the graphs illustrating the pressure of wheel sets on the tracks and the pressure load on the door of the carriage

Engineered T cells Flt around their targets

Antigen escape by solid tumors has limited the efficacy of genetically modified T cells. T cells engineered to secrete the cytokine Flt3L induce the activation of endogenous T cells, enabling a broader repertoire of tumor antigens to be targeted via the expansion of intratumoral antigen presenting cells, significantly improving tumor responses