Study flow chart.

<p>The total follow-up time was 1,592.5 person years at risk (PYAR). The median age was 13 years (Inter-quartile range (IQR) 5, 28; range 6 months-90 years). LLINs ownership was high (71.49%, 2766/3869) and their use varied significantly by month, with July, at the start of the transmission season, having the lowest proportion (52.22%, 1916/3669), and increasing significantly from August (87.05%, 2811/3229) to October (94.04%, 2809/2987), p<0.01 (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0187059#pone.0187059.g002" target="_blank">Fig 2</a>).</p

Variation <i>An</i>. <i>gambiae s</i>.<i>l</i> species composition across the transmission season.

<p>Vector parity was significantly higher in URR-S and URR-N than in the other 4 regions (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0187059#pone.0187059.t011" target="_blank">Table 11</a>).</p

Risk factors for ≥ 2 episodes of malaria infection.

<p>Risk factors for ≥ 2 episodes of malaria infection.</p

Kaplan Meier survival curves comparing the time to clinical malaria among household members with or without at least a malaria-infected individual at the start of the transmission season.

<p>After adjusting for age, gender, travel, LLIN use and sleeping outdoors, the risk remained significantly higher only for WCR (HR = 4.0, 95% CI: 2.1–7.5, p<0.01) and URR-N (HR 1.5, 95% CI: 1.1–2.1, p = 0.02).</p

Risk factors of <i>P</i>. <i>falciparum</i> infection at the start of the transmission season.

<p>Risk factors of <i>P</i>. <i>falciparum</i> infection at the start of the transmission season.</p

<i>An</i>. <i>gambiae s</i>.<i>l</i>. indoor and outdoor biting estimated by HLC, by region^*.

<p><i>An</i>. <i>gambiae s</i>.<i>l</i>. indoor and outdoor biting estimated by HLC, by region^{<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0187059#t008fn001" target="_blank">*</a>}.</p

<i>An</i>. <i>gambiae s</i>.<i>l</i>. indoor and outdoor biting by month^*.

<p><i>An</i>. <i>gambiae s</i>.<i>l</i>. indoor and outdoor biting by month^{<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0187059#t009fn001" target="_blank">*</a>}.</p

<i>An</i>. <i>gambiae s</i>.<i>l</i>. indoor and outdoor biting patterns across study sites.

<p><i>An</i>. <i>gambiae s</i>.<i>l</i>. indoor and outdoor biting patterns across study sites.</p

Entomological inoculation rates (EIR) and species composition by region.

<p>Entomological inoculation rates (EIR) and species composition by region.</p

Vector parity by region.

<p>Vector parity by region.</p