Annual Hepatocellular Carcinoma Incidence and Mortality Rates in Chronic Hepatitis B Patients.

<p>Annual Hepatocellular Carcinoma Incidence and Mortality Rates in Chronic Hepatitis B Patients.</p

Annual incidence of hepatocellular carcinoma in untreated hepatitis B patients (events per 100 person-year).

<p>Random effects meta-analysis with subgroups according to HCC screening.</p

Annual incidence of hepatocellular carcinoma in untreated hepatitis B patients with cirrhosis (events per 100 person-year). Random effects meta-analysis.

<p>Annual incidence of hepatocellular carcinoma in untreated hepatitis B patients with cirrhosis (events per 100 person-year). Random effects meta-analysis.</p

Trial flow diagram.

<p>Trial flow diagram.</p

Bias assessment.

<p>Bias assessment.</p

Annual mortality (events per 100 person-year) in untreated hepatitis B patients. Random effects meta-analysis.

<p>Annual mortality (events per 100 person-year) in untreated hepatitis B patients. Random effects meta-analysis.</p

Additional file 1: of Antifibrotic and molecular aspects of rifaximin in alcoholic liver disease: study protocol for a randomized controlled trial

SPIRIT 2013 checklist: recommended items to address in a clinical trial protocol and related documents. (DOC 121 kb