1,292 research outputs found
Effects of cytokinins, cytokinin ribosides and their analogs on the viability of normal and neoplastic human cells
We examined the effects of some cytokinins and cytokinin ribosides including a series of adenosine analogs differently substituted in the N(6) position, along with some hypoxanthine derivatives on the viability of normal and neoplastic human cells. Cytokinins such as trans-zeatin, isopentenyladenine and benzyladenine do not show any effect, while cytokinin ribosides such as trans-zeatin riboside, isopentenyladenosine, and benzylaminopurine riboside impair the viability of normal and neoplastic cells, apart from colon carcinoma LoVo cells
The effect of shear stress reduction on endothelial cells : a microfluidic study of the actin cytoskeleton
Reduced blood flow, as occurring in ischemia or resulting from exposure to microgravity such as encountered in space flights, induces a decrease in the level of shear stress sensed by endothelial cells forming the inner part of blood vessels. In the present study, we use a microvasculature-on-a-chip device in order to investigate in vitro the effect of such a reduction in shear stress on shear-adapted endothelial cells. We find that, within 1 h of exposition to reduced wall shear stress, human umbilical vein endothelial cells undergo reorganization of their actin skeleton with a decrease in the number of stress fibers and actin being recruited into the cells' peripheral band, indicating a fairly fast change in the cells' phenotype due to altered flow
Thermally assisted magnetization reversal in the presence of a spin-transfer torque
We propose a generalized stochastic Landau-Lifshitz equation and its
corresponding Fokker-Planck equation for the magnetization dynamics in the
presence of spin transfer torques. Since the spin transfer torque can pump a
magnetic energy into the magnetic system, the equilibrium temperature of the
magnetic system is ill-defined. We introduce an effective temperature based on
a stationary solution of the Fokker-Planck equation. In the limit of high
energy barriers, the law of thermal agitation is derived. We find that the
N\'{e}el-Brown relaxation formula remains valid as long as we replace the
temperature by an effective one that is linearly dependent of the spin torque.
We carry out the numerical integration of the stochastic Landau-Lifshitz
equation to support our theory. Our results agree with existing experimental
data.Comment: 5 figure
Lifetime distributions in the methods of non-equilibrium statistical operator and superstatistics
A family of non-equilibrium statistical operators is introduced which differ
by the system age distribution over which the quasi-equilibrium (relevant)
distribution is averaged. To describe the nonequilibrium states of a system we
introduce a new thermodynamic parameter - the lifetime of a system.
Superstatistics, introduced in works of Beck and Cohen [Physica A \textbf{322},
(2003), 267] as fluctuating quantities of intensive thermodynamical parameters,
are obtained from the statistical distribution of lifetime (random time to the
system degeneracy) considered as a thermodynamical parameter. It is suggested
to set the mixing distribution of the fluctuating parameter in the
superstatistics theory in the form of the piecewise continuous functions. The
distribution of lifetime in such systems has different form on the different
stages of evolution of the system. The account of the past stages of the
evolution of a system can have a substantial impact on the non-equilibrium
behaviour of the system in a present time moment.Comment: 18 page
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