A novel fluorescent "turn-on" chemosensor for nanomolar detection of Fe(III) from aqueous solution and its application in living cells imaging

An electronically active and spectral sensitive fluorescent “turn-on” chemosensor (BTP-1) based on the benzo-thiazolo-pyrimidine unit was designed and synthesized for the highly selective and sensitive detection of Fe³⁺ from aqueous medium. With Fe³⁺, the sensor BTP-1 showed a remarkable fluorescence enhancement at 554 nm (λex=314 nm) due to the inhibition of photo-induced electron transfer. The sensor formed a host-guest complex in 1:1 stoichiometry with the detection limit down to 0.74 nM. Further, the sensor was successfully utilized for the qualitative and quantitative intracellular detection of Fe³⁺ in two liver cell lines i.e., HepG2 cells (human hepatocellular liver carcinoma cell line) and HL-7701 cells (human normal liver cell line) by a confocal imaging technique

Fluid friction in incompressible laminar convection: Reynolds' analogy revisited for variable fluid properties

The Reynolds' analogy between the Stanton number (St) and the skin friction coefficient (cf) is popularly believed to hold when St increases with increasing cf, for simple situations. In this investigation, the validity of Reynolds' analogy between St and cf for micro-convection of liquids with variations in fluid properties is re-examined. It is found that the Sieder-Tate's property-ratio method for obtaining Nusselt number corrections is theoretically based on the validity of Reynolds' analogy. The inverse dependence of Reynolds number and skin friction coefficient is the basis for validity of the Reynolds' analogy, in convective flows with fluid property variations. This leads to the unexpected outcome that Reynolds' analogy now results in St increasing with decreasing cf. These results and their analyses indicate that the validity of Reynolds' analogy is based on deeper foundations, and the well-known validity criterion is a special case

<span style="font-size:14.0pt;line-height: 115%;font-family:"Times New Roman";mso-fareast-font-family:"Times New Roman"; color:black;mso-ansi-language:EN-IN;mso-fareast-language:EN-IN;mso-bidi-language: HI" lang="EN-IN">Eco-friendly Pest Management Using Monoterpenoids-III: Antibacterial Efficacy of Carvacrol Derivatives^#</span>

1086-1089<span style="font-size:14.0pt;line-height: 115%;font-family:" times="" new="" roman";mso-fareast-font-family:"times="" roman";="" color:black;mso-ansi-language:en-in;mso-fareast-language:en-in;mso-bidi-language:="" hi"="" lang="EN-IN">Monoterpenoids are the natural products having pest management potency against different agricultural as well as public health pests. Ether and ester derivatives of carvacrol, [2-methyl-5- (1-methyl ethyl) phenol], a natural phenolic monoterpenoid, were synthesized and evaluated for their antibacterial activity against B.megaterium, B.japonicum ,B.polymyxa and B. substilits to establish structure-activity relationships. In overall studies, carvacrol esters exhibited better antibacterial potency and efficacy than ethers. An introduction of aliphatic side chains with increasing methylene group and olefine double bond reflected least effect on activity. However, aromatic moiety, additional olefinic bond and also carboxylic group in the side chain resulted in the compounds with improved and better antibacterial potency over the parent molecule.</span

Microwave Assisted One Pot Synthesis of <i>N</i>-Substituted Phenyl-4-Thiophenyl- <span style="font-size:14.0pt;line-height:115%;font-family:"Times New Roman"; mso-fareast-font-family:"Times New Roman";color:black;mso-ansi-language:EN-IN; mso-fareast-language:EN-IN;mso-bidi-language:HI" lang="EN-IN">2-Azetidinones as Potent Antimicrobial Agents^†#</span>

1024-1026Simple, rapid, clean and environmentally friendly methods for the synthesis of Schiffs bases and their cycloaddition with acetyl chloride to N-substituted phenyl-4-thiophenyl-2-azetidinones under microwave irradiation are reported

Synthesis, characterization and antimicrobial activities of metal complexes of 2-formyl thymol oxime

665-669 Metal to ligand (1: 2) complexes with molecular formula [M(HL)2]n [HL = anionic form of 2-formyl thymol oxime, M = metal (II) ion] of 2-formyl thymol oxime (H2L) and its manganese, iron, cobalt, nickel, copper and zinc complexes have been prepared and characterized by elemental analysis, magnetic measurements, molar conductivity, IR and UV-Visible spectroscopy. Complexes were tested for antimicrobial activities against Escherichia coli, Pseudomonas putida, P. fluorescense and Bradyrhizobium japonicum and fungal cultures Aspergillus niger, A. flavus, Fusarium oxysporum, and Alternaria alternata. </smarttagtype

Solid supported synthesis of 2-mercaptobenzimidazole derivatives using microwaves

374-3762–Mercaptobenzimidazole(MBI) derivatives having substituent at either nitrogen or sulphur of a thioamide ring exhibit biological activity. MBI derivatives were synthesized in moderate to high yields in a short time to give pure required products by using solid support such as silica gel / neutral alumina / fly ash under microwave assisted solventless conditions