1 research outputs found
Pure Water-Induced Dehalogenation of 2,4-Di-<i>tert</i>-amino-6-substituted-5-halogenopyrimidines
Dehalogenation of
5-halogenopyrimidine derivatives in boiling pure
water was accomplished in high yields. The substrate and pure water
are the only two reaction components in this process. Dehalogenation
takes place in the absence of any catalysts, additives, basic, or
acidic conditions, introducing water as a potential dehalogenation
reagent