Additional file 1 of Fatal overdose from injection of human growth hormone; a case report and review of the literature

Additional file 1: Supplementary Figure 1: The electrocardiogram of patient. Left atrial abnormality is visible. According to Romhilt-Estes criteria, the second part of P wave deflection in lead V1 represents the duration of ≥ 40 msec and the depth of ≥ 1 mm

Additional file 1 of The effect of sodium-glucose co-transporter-2 (SGLT2) inhibitors on blood interleukin-6 concentration: a systematic review and meta-analysis of randomized controlled trials

Additional file 1: Table S1. We have searched PubMed, Embase, and Scopus databases using the terms below, PubMed for example (Updated to November 2023). Table S1. PICO inclusion criteria. Table S1. Meta-regression analysis of demographic and clinical variables on IL-6 lowering effect of SGLT2 inhibitors. Figure S1. Forest plot of the effect of SGLT2 inhibitor drugs on interleukin-6 based on the trial duration. Figure S2. Forest plot of the effect of SGLT2 inhibitor drugs on interleukin-6 based on the level of HbA1c. Figure S3. Relationship between level of HbA1c and interleukin-6 lowering effect of SGLT2 inhibitors. SGLT2 inhibitor: Sodium-glucose co-transporter-2 inhibitors. Figure S4. Relationship between male sex and interleukin-6 lowering effect of SGLT2 inhibitors. SGLT2 inhibitor: Sodium-glucose co-transporter-2 inhibitors. Figure S5. Relationship between age and interleukin-6 lowering effect of SGLT2 inhibitors. SGLT2 inhibitor: Sodium-glucose co-transporter-2 inhibitors. Figure S1. Risk of bias quality assessment results using ROB-2 tool. Figure S2. Funnel plot with pseudo 95% confidence limits demonstrating the SMD of interlukin-6 for each trial against their corresponding SEs. SMD: Standardized mean difference, SE: Standard error. Egger regression test had the p-value of 0.061. Figure S3. Galbraith plot to assess heterogeneity of the effects of SGLT2 inhibitor drugs on interleukin-6. SGLT2 inhibitor: Sodium-glucose co-transporter-2 inhibitors. Figure S4. The sensitivity analysis of the included studies using the leave-one-out (Left) and cumulative (Right) approaches. Table S1. Sensitivity analyses to assess the effect of different correlation coefficients on the main results