Combining a Click–Multicomponent Reaction: One-Pot Synthesis of 1,2,3-Triazol-4-ylmethyl 3-Amino-5,10-dihydro-5,10-dioxo-1<i>H</i>-pyrazolo[1,2-<i>b</i>]phthalazine-2-carboxylate Derivatives

<div><p></p><p>(1,2,3-Triazol-4-yl)methyl-3-amino-5,10-dihydro-5,10-dioxo-1<i>H</i>-pyrazolo[1,2-<i>b</i>]phthalazine-2-carboxylate derivatives were synthesized by a four-component, one-pot condensation reaction of benzaldehyde derivatives, an active methylene compound (prop-2-ynyl-2-cyanoacetate), azides, and phthalhydrazide in the presence of Cu(OAc)₂/sodium ascorbate as catalysts and 1-methyl-1<i>H</i>-imidazolium trifluoroacetate ([Hmim]TFA) as an ionic liquid medium in good to excellent yields.</p> </div