A Case Study Based Slope Stability Analysis at Chittagong City, Bangladesh

Heavy rainfall occurs almost every year in Bangladesh and induces landslides in the hilly regions of this country. Among them the Chittagong City has the worst scenario―as there lives a dense population, extending from the plain lands to the hilly area. So, for risk mitigation and management in this landslide prone city, slope safety margin should be determined. From this context, this article presents factor of safety (FS) values in terms of landslide hazard at Chittagong city, based on geotechnical parameters and slope geometry. Thus a preliminary idea on the allowable stress for slope design could be made from this study. In total, 16 hazard sites of the 2007 and 2008, rainfall induced, landslides were examined as a case study along with subsequent collection of in situ soil samples of the failed slopes for geotechnical laboratory analysis. For FS calculation, the limit equilibrium method for infinite slopes was deployed along with the Cousins’ stability chart. FS values from 0.94 to 1.57 were found at the hazard sites. The results imply that FS value more than 1.57 should be used for slope safety margin. Moreover, from a probabilistic approach, the authors recommend FS > 1.80 as optimum value for the region. Furthermore, a relationship between slope height to slope length ratio, or slope angle and FS was established for this region for a quick calibration of FS value by simple on-field measurement of slope parameters. It is expected that this scenario based finding would contribute in mitigation of landslide hazard risk at the study area. Additionally, site specific FS values were presented in a map by color indexing. This research could ascertain the location wise slope strength requirement and be considered as a guideline for future calculation for slope safety design against rainfall triggered landslides in this city

Variations in hydrostratigraphy and groundwater quality between major geomorphic units of the Western Ganges Delta plain, SW Bangladesh

Abstract Relationships among geomorphology, hydrostratigraphy, and groundwater quality with special emphasis on arsenic and salinity have been analyzed in the Bangladesh part of the Western Ganges Delta (WGD). On the basis of the presence of characteristic geomorphic features, the study area is divided into two geomorphic units: fluvial deltaic plain (FDP) and fluvio-tidal deltaic plain (FTDP). Lithostratigraphic sections demonstrate that FDP is composed predominately of sandy material whereas FTDP is characterized by alternation of sand and clay/silty clay material. Hydrostratigraphically, FDP is characterized as a single aquifer system, whereas FTDP is a complex multi-aquifer system. Spatial distributions of arsenic concentrations in groundwater reveal that elevated arsenic (>0.01 mg/l) occurs mostly in the FDP. Occurrences of high arsenic in deeper part of the aquifer system (>100 m) in the FDP, particularly in the south-western part, is probably due to the absence of any prominent impermeable layer between the shallow and deeper part of the aquifer system. Distributions of chloride concentrations show an increasing trend in groundwater salinity from north to south, i.e., from FDP to FTDP

Epidemiology and outcomes of hospital-acquired bloodstream infections in intensive care unit patients: the EUROBACT-2 international cohort study

Purpose In the critically ill, hospital-acquired bloodstream infections (HA-BSI) are associated with significant mortality. Granular data are required for optimizing management, and developing guidelines and clinical trials. Methods We carried out a prospective international cohort study of adult patients (≥ 18 years of age) with HA-BSI treated in intensive care units (ICUs) between June 2019 and February 2021. Results 2600 patients from 333 ICUs in 52 countries were included. 78% HA-BSI were ICU-acquired. Median Sequential Organ Failure Assessment (SOFA) score was 8 [IQR 5; 11] at HA-BSI diagnosis. Most frequent sources of infection included pneumonia (26.7%) and intravascular catheters (26.4%). Most frequent pathogens were Gram-negative bacteria (59.0%), predominantly Klebsiella spp. (27.9%), Acinetobacter spp. (20.3%), Escherichia coli (15.8%), and Pseudomonas spp. (14.3%). Carbapenem resistance was present in 37.8%, 84.6%, 7.4%, and 33.2%, respectively. Difficult-to-treat resistance (DTR) was present in 23.5% and pan-drug resistance in 1.5%. Antimicrobial therapy was deemed adequate within 24 h for 51.5%. Antimicrobial resistance was associated with longer delays to adequate antimicrobial therapy. Source control was needed in 52.5% but not achieved in 18.2%. Mortality was 37.1%, and only 16.1% had been discharged alive from hospital by day-28. Conclusions HA-BSI was frequently caused by Gram-negative, carbapenem-resistant and DTR pathogens. Antimicrobial resistance led to delays in adequate antimicrobial therapy. Mortality was high, and at day-28 only a minority of the patients were discharged alive from the hospital. Prevention of antimicrobial resistance and focusing on adequate antimicrobial therapy and source control are important to optimize patient management and outcomes