Experiment 1 results—CUSE (a-h) and SSI (i-p) shear wave speed maps.

<p>(a, i) Gelatin background (b, j) 2mm kidney stone (c, k) 3mm kidney stone (d, l) 5mm kidney stone (e, m) 6mm kidney stone (f, n) 9mm kidney stone (g, o) 11mm kidney stone (h, p) 15mm kidney stone.</p

E_mean relative error values for a 7mm intact kidney stone (coarse), 8mm cluster distribution of ground kidney stone, 15mm regional scattered distribution of ground kidney stone, and gelatin background.

<p>E_mean relative error values for a 7mm intact kidney stone (coarse), 8mm cluster distribution of ground kidney stone, 15mm regional scattered distribution of ground kidney stone, and gelatin background.</p

SSI method.

<p>(a) Excitation of medium by generating a sequence of acoustic radiation force points parallel to the beam axis. (b) Propagation of the two shear waves in opposite directions. (c) Reconstruction of a 2D elasticity map from measured local displacement.</p

Minimum, mean and maximum elasticity parameters by kidney stone size within a 2cm diameter ROI.

<p>*Background without calcifications.</p><p>Minimum, mean and maximum elasticity parameters by kidney stone size within a 2cm diameter ROI.</p

CUSE method.

<p>(a) Excitation of the medium by using four equidistant acoustic radiation force beams. (b) Detection of LR (<i>red arrows</i>) and RL (<i>blue arrows</i>) shear wave propagations. (c) Reconstruction of a 2D shear wave map from the calculated shear wave propagation speed.</p

Minimum, mean and maximum elasticity values by inclusion feature within a 2cm ROI.

<p>* Without calcifications.</p><p>Minimum, mean and maximum elasticity values by inclusion feature within a 2cm ROI.</p

Effect of Calcifications on Breast Ultrasound Shear Wave Elastography: An Investigational Study - Fig 13

<p>(a) Right breast mediolateral mammogram revealing a mass involving macrocalcifications (red arrow). (b) B-mode ultrasound presenting a 2.3 cm irregular area of mixed echogenicity (blue arrow). (c) CUSE image showing high stiffness on the mass; the color bar indicates the speed of the shear wave.</p

Experiment 2.

<p>(a) Inclusion with 7mm intact kidney stone. (b) Inclusion with clustered distribution of ground kidney stone. (c) Inclusion with regional scattered distribution of ground kidney stone.</p

Effect of Calcifications on Breast Ultrasound Shear Wave Elastography: An Investigational Study - Fig 11

<p>(a) Mediolateral oblique mammogram revealing a group of macrocalcifications associated with a soft tissue mass (red arrow). (b) Clinical B-mode ultrasound revealing a 6mm mass (blue arrow) with heterogeneous echogenicity. (c) CUSE image showing high stiffness along the vertical axis of the mass. The color bar indicates the speed of the shear wave.</p

Experiment 2 results: CUSE (a-d) and SSI (e-h) shear wave speed maps.

<p>(a, e) Gelatin background (b, f) 15mm regional scattered distribution of ground kidney stone (c, g) 8mm clustered distribution of ground kidney stone (d, h) 7mm intact kidney stone.</p