ネパールの中部及び西部タライ農業における気候変動への適応に及ぼす要因分析

内容の要約広島大学(Hiroshima University)博士(国際協力学)Doctor of Philosophy in International Cooperation Studiesdoctora

Climate-Smart Agriculture (CSA): A Systematic Assessment and Analysis of Policies/plans and Practices in South Asia, Particularly Focusing on Nepal and India <Article>

Climate-smart agriculture (CSA) is a promising concept in agriculture to deal with the climate change impacts through innovative policies/plans, approaches, and practices. This study presents the assessment and analysis of the concept, policies, and practices in relation to CSA in South Asia, particularly focusing on Nepal and India. Both countries have different climatic contexts, but most of the farmers rely on rainfall for agriculture, which is the main source of livelihood and food security. This study applied the systematic review of published papers relating to climate policies/plans and CSA practices in Science Direct (SD) and Springer Link (SL) for the period of 2009 to 2019 with specific inclusion and exclusion criteria. It was found that these studies had specifically focused on climate policies/plans and CSA practices chiefly focusing on agriculture and food security in these countries. However, the CSA practices were different based on the local climatic contexts either initiated by farmers themselves or supported by the government, non-government, and other agencies. Farmer-initiated CSA practices were mostly spontaneous, whereas institution-supported practices were planned, guided by the climate policies/plans. However, these policies/plans and practices lacked specific indicators to assess the successes. Many of these practices were common prior to the emergence of the CSA concept and approach. Thus, it is important to define and understand the CSA concept, approaches, and mechanisms through research, development, and promotion at the national as well as local levels.This paper is a partial output of the JSPS Bilateral Joint Research Project (JPJSBP 120197904: 2019), “Moving Towards Climate Resilient Agriculture: Understanding the Factors Influencing Adoptian in India and Japan”, Principal Investigator: Maharjan, Keshav Lall, Professor, Hiroshima University

Review of Climate Policies and Roles of Institutions in the Policy Formulation and Implementation of Adaptation Plans and Strategies in Nepal

Adaptation is undeniably crucial to address the complex issues and impacts of climate change at all levels in Nepal. The favorable policies and adaptive capacities of the communities are equally important to adapt to the climatic risks and hazards. The policies such as NAPA, national climate change policy and LAPA have been formulated in Nepal to address these climatic risks and hazards at national and local levels. Correspondingly, the communities and institutions are also adapting through their own efforts and initiatives. These institutions have contributed vital roles in policy formulation and effective implementation of adaptation plans and strategies as guided by NAPA and LAPA. This review paper has explored and analyzed the climate policies in Nepal, strengths and gaps in such policies, roles of local institutions in the policy formulation and effective implementation of adaptation plans and strategies. It has reviewed and analyzed the existing literature relating to climate change policies and adaptation plans and strategies. The paper highlights the climate policies, followed by roles of institutions in effective adaptation and the analysis of climate change adaptations especially focusing on mobility, storage, livelihood diversification, communal pooling and market exchange

Formulation and Comparative in-vitro Evaluation of Mucoadhesive Buccal Tablets of Furosemide

This study was conducted to develop mucoadhesive buccal tablet of Frusemide. A Mucoadhesive buccal tablet of Frusemide were prepared by using wet granulation method using dfferent polymer such as HPMC k 100, Carbopol-940 in different ratio. Tablets were analysed by measuring different parameters thickness, hardness weight uniformity, drug content uniformity, LOD, sweeling index, invitro dissolution study and solubility. The tablets were evaluated for in vitro release in pH 6.8-phosphate buffer for 12 hr in standard dissolution apparatus. Mucoadhesion strength was increased with increase in the concentration of carbopol. In order to determine the mode of release, the data was subjected to Zero order, first order, Higuchi and Peppas diffusion model

Determinants of agriculture biodiversity in Western Terai landscape complex of Nepal

The study explored agriculture biodiversity around protected areas and identified factors affecting diversity of agriculture biodiversity in farming households. The study analyzed the data collected from household survey of about 907 farmers from Western-Terai Landscape Complex of Nepal. Intra-species and inter-species richness and evenness in agriculture landscape were estimated and compared across a spectrum of land-uses. The study identified different social, economic, technological and ecological factors affecting the richness of intra-species and inter-species diversity of agriculture biodiversity using generalized linear regression models. Technology index, information index, food security, animal holding, ethnicity, irrigation facility and land-use were found as major variables affecting agriculture. The results also indicated that buffer zones had higher diversity than other land-uses, indicating positive effects of protected-land on surrounding agriculture biodiversity. Results supported need of coordinated efforts to mainstream agriculture biodiversity conservation with landscape conservation plans and socio-economic developments of the region

Determinants of agriculture biodiversity in Western Terai landscape complex of Nepal

The study explored agriculture biodiversity around protected areas and identified factors affecting diversity of agriculture biodiversity in farming households. The study analyzed the data collected from household survey of about 907 farmers from Western-Terai Landscape Complex of Nepal. Intra-species and inter-species richness and evenness in agriculture landscape were estimated and compared across a spectrum of land-uses. The study identified different social, economic, technological and ecological factors affecting the richness of intra-species and inter-species diversity of agriculture biodiversity using generalized linear regression models. Technology index, information index, food security, animal holding, ethnicity, irrigation facility and land-use were found as major variables affecting agriculture. The results also indicated that buffer zones had higher diversity than other land-uses, indicating positive effects of protected-land on surrounding agriculture biodiversity. Results supported need of coordinated efforts to mainstream agriculture biodiversity conservation with landscape conservation plans and socio-economic developments of the region

Effect of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker initiation on organ support-free days in patients hospitalized with COVID-19

IMPORTANCE Overactivation of the renin-angiotensin system (RAS) may contribute to poor clinical outcomes in patients with COVID-19. Objective To determine whether angiotensin-converting enzyme (ACE) inhibitor or angiotensin receptor blocker (ARB) initiation improves outcomes in patients hospitalized for COVID-19. DESIGN, SETTING, AND PARTICIPANTS In an ongoing, adaptive platform randomized clinical trial, 721 critically ill and 58 non–critically ill hospitalized adults were randomized to receive an RAS inhibitor or control between March 16, 2021, and February 25, 2022, at 69 sites in 7 countries (final follow-up on June 1, 2022). INTERVENTIONS Patients were randomized to receive open-label initiation of an ACE inhibitor (n = 257), ARB (n = 248), ARB in combination with DMX-200 (a chemokine receptor-2 inhibitor; n = 10), or no RAS inhibitor (control; n = 264) for up to 10 days. MAIN OUTCOMES AND MEASURES The primary outcome was organ support–free days, a composite of hospital survival and days alive without cardiovascular or respiratory organ support through 21 days. The primary analysis was a bayesian cumulative logistic model. Odds ratios (ORs) greater than 1 represent improved outcomes. RESULTS On February 25, 2022, enrollment was discontinued due to safety concerns. Among 679 critically ill patients with available primary outcome data, the median age was 56 years and 239 participants (35.2%) were women. Median (IQR) organ support–free days among critically ill patients was 10 (–1 to 16) in the ACE inhibitor group (n = 231), 8 (–1 to 17) in the ARB group (n = 217), and 12 (0 to 17) in the control group (n = 231) (median adjusted odds ratios of 0.77 [95% bayesian credible interval, 0.58-1.06] for improvement for ACE inhibitor and 0.76 [95% credible interval, 0.56-1.05] for ARB compared with control). The posterior probabilities that ACE inhibitors and ARBs worsened organ support–free days compared with control were 94.9% and 95.4%, respectively. Hospital survival occurred in 166 of 231 critically ill participants (71.9%) in the ACE inhibitor group, 152 of 217 (70.0%) in the ARB group, and 182 of 231 (78.8%) in the control group (posterior probabilities that ACE inhibitor and ARB worsened hospital survival compared with control were 95.3% and 98.1%, respectively). CONCLUSIONS AND RELEVANCE In this trial, among critically ill adults with COVID-19, initiation of an ACE inhibitor or ARB did not improve, and likely worsened, clinical outcomes. TRIAL REGISTRATION ClinicalTrials.gov Identifier: NCT0273570

Choices of Research Methodologies on Climate Change Adaptation Especially Focusing on Agriculture Sector: A Systematic Review

A rapid increase in climate researches by applying diverse methodologies and approaches in recent decades. These researches have directly or indirectly contributed in better understanding of climate issues, risks and vulnerabilities. It has improved awareness and capacities of the public and communities to adapt to the vulnerabilities and impacts. It, further, contributes in formulation of climate policies and plans to address climate risks and vulnerabilities at the local and national levels. Appropriate methodologies lead to better results in the researches. This paper has applied systematic review of the published papers (2010 -2017) to understand the general and specific research methodologies in climate discourse especially in Web of Science (WS), Springer Link (SL) and Science Direct (SD). Altogether, 37 journal papers (10 WS, 13 SL and 14 SD) were selected for the detail analysis based on the assessment of abstracts, which was mainly concentrated on research methodologies specializing in agriculture. In the process, the authors have analyzed the contents, research methodologies, data analysis, and geographical coverages. The analysis, further, concentrated on the scope and limitations of the research methodologies used. Wide-ranging research methodologies are found that are applied by the researchers in the climate change discourse. Some researchers have applied general research methodologies whereas others have used specific research methodologies and model analysis. Furthermore, it is comprehended that the combination of research methodologies and approaches through focus group discussion together with household survey and model analysis is the effective way for the research by using quantitative and qualitative data