12 research outputs found
Research note: occurrence of Biomphalaria tenagophila and disappearance of Biomphalaria straminea in Paracambi, RJ, Brazil
Genital schistosomiasis mansoni concomitant to genital tumor in areas of low endemicity: challenging diagnosis
Genital infection by Schistosoma mansoni is usually misdiagnosed in individuals who reside in, or travel to endemic areas. We describe two cases of genital tumor associated with S. mansoni infection manifested by methrorragy. Surgical specimens revealed leiomyomas in both cases associated with S. mansoni. In one of them, granulomas were found in the ovary and in the other they were found in the uterine tube. Although none presented intestinal/hepatic disease, fecal egg excretion was detected in one. Both had elevated pretreatment antibody reactivity to S. mansoni antigen, but follow-up showed different outcomes. Schistosomiasis should be considered as a diagnosis in individuals with methrorragy residing in or having traveled to endemic areas. Since diagnosis follows genital amputation, and cure control is troublesome, improvement of diagnostic tools and follow-up markers are important priorities to decrease schistosomiasis morbidity
Genital schistosomiasis mansoni concomitant to genital tumor in areas of low endemicity: challenging diagnosis
Schistosomiasis in a Low Prevalence Area: Incomplete Urbanization Increasing Risk of Infection in Paracambi, RJ, Brazil
The risk of schistosomiasis infection and heavy infection in the
locality of Sabugo was evaluated in relation to housing in areas with
different urbanization development and to residential supply with
snail-infested water. Critical sanitary conditions were found in areas
of incomplete urbanization, where healthy water supply sources were
scarce, and draining of sewage, without previous treatment, was made
directly to the water-bodies used for domestic and leisure activities,
despite being Biomphalaria tenagophila snail breeding-places. Stool
examinations (Kato-Katz and Lutz methods) showed prevalence of 2.9%,
mean intensity of 79 eggs per gram of stool and 47% of positive cases
presenting intense infection. The use of snail-contaminated water for
domestic purposes was considered a risk factor for infection. It is
concluded that incomplete urbanization would facilitate transmission,
probably enhancing the intensity of infection and that a low prevalence
could hide a highly focal transmission. The relevance of these facts
upon the efficiency of epidemiologic study methods and disease control
planning are then discussed. Key words
An ecological field study of the water-rat Nectomys squamipes as a wild reservoir indicator of Schistosoma mansoni transmission in an endemic area
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Previous issue date: 2006Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Medicina Tropical. Laboratório de Biologia e Controle da Esquistossomose. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Medicina Tropical. Laboratório de Biologia e Controle da Esquistossomose. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Medicina Tropical. Laboratório de Biologia e Controle da Esquistossomose. Rio de Janeiro, RJ. Brasil.Universidade Federal do Rio Grande do Sul. Programa de Pós-Graduação em Biologia Animal. Porto Alegre, RS, Brasil.Universidade Federal do Rio Grande do Sul. Programa de Pós-Graduação em Biologia Animal. Porto Alegre, RS, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Biologia. Laboratório de Avaliação e Promoção da Saúde Ambiental. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Biologia. Laboratório de Avaliação e Promoção da Saúde Ambiental. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Biologia. Laboratório de Avaliação e Promoção da Saúde Ambiental. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio de Janeiro. Instituto de Microbiologia Paulo de Góes. Departamento de Imunologia. Laboratório de Sorologia. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio de Janeiro. Instituto de Microbiologia Paulo de Góes. Departamento de Imunologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Medicina Tropical. Laboratório de Biologia e Controle da Esquistossomose. Rio de Janeiro, RJ. Brasil.Small mammals are found naturally infected by Schistosoma mansoni, becoming a confounding factor for control
programs of schistosomiasis in endemic areas. The aims of this study were: to investigate the infection rates by S.
mansoni on the water-rat Nectomys squamipes during four years in endemic areas of Sumidouro, state of Rio de
Janeiro, using mark-recapture technique; to compare two diagnostic methods for schistosomiasis; and to evaluate
the effects of the chemotherapy in the human infected population on the rodent infection rates. The rodent infection
rates of S. mansoni increased when rodent population sizes were lower. Coprology and serology results presented
the same trends along time and were correlated. Serology could detect recent infection, including the false negatives
in the coprology. The chemotherapy in the humans could not interrupt the rodent infection. Rodents can
increase the schistosomiaisis transmission where it already exists, they probably maintain the transmission cycle in
the nature and can be considered as biological indicators of the transmission sites of this parasite since they are
highly susceptible to infection. The water-rats may present different levels of importance in the transmission dynamics
of S. mansoni infection cycle for each area, and can be considered important wild-reservoirs of this human
disease
An ecological field study of the water-rat Nectomys squamipes as a wild reservoir indicator of Schistosoma mansoni transmission in an endemic area
Small mammals are found naturally infected by Schistosoma mansoni,
becoming a confounding factor for control programs of schistosomiasis
in endemic areas. The aims of this study were: to investigate the
infection rates by S. mansoni on the water-rat Nectomys squamipes
during four years in endemic areas of Sumidouro, state of Rio de
Janeiro, using mark-recapture technique; to compare two diagnostic
methods for schistosomiasis; and to evaluate the effects of the
chemotherapy in the human infected population on the rodent infection
rates. The rodent infection rates of S. mansoni increased when rodent
population sizes were lower. Coprology and serology results presented
the same trends along time and were correlated. Serology could detect
recent infection, including the false negatives in the coprology. The
chemotherapy in the humans could not interrupt the rodent infection.
Rodents can increase the schistosomiaisis transmission where it already
exists, they probably maintain the transmission cycle in the nature and
can be considered as biological indicators of the transmission sites of
this parasite since they are highly susceptible to infection. The
water-rats may present different levels of importance in the
transmission dynamics of S. mansoni infection cycle for each area, and
can be considered important wild-reservoirs of this human disease