8 research outputs found
Respiratory events in ward are associated with later intensive care unit (ICU) admission and hospital mortality in onco-hematology patients not admitted to ICU after a first request
<div><p>Introduction</p><p>Prognostic impact of delayed intensive care unit(ICU) admission in critically ill cancer patients remains debatable. We determined predictive factors for later ICU admission and mortality in cancer patients initially not admitted after their first ICU request.</p><p>Methods</p><p>All cancer patients referred for an emergency ICU admission between 1 January 2012 and 31 August 2013 were included.</p><p>Results</p><p>Totally, 246(54.8%) patients were immediately admitted. Among 203(45.2%) patients denied at the first request, 54(26.6%) were admitted later. A former ICU stay [OR: 2.75(1.12–6.75)], a request based on a clinical respiratory event[OR: 2.6(1.35–5.02)] and neutropenia[OR: 2.25(1.06–4.8)] were independently associated with later ICU admission. Survival of patients admitted immediately and later did not differ at ICU(78.5% and 70.4%, respectively; <i>p</i> = 0.2) or hospital(74% and 66%, respectively; <i>p</i> = 0.24) discharge. Hospital mortality of patients initially not admitted was 29.7% and independently associated with malignancy progression[OR: 3.15(1.6–6.19)], allogeneic hematopoietic stem cell transplantation[OR: 2.5(1.06–5.89)], a request based on a clinical respiratory event[OR: 2.36(1.22–4.56)] and severe sepsis[OR: 0.27(0.08–0.99)].</p><p>Conclusion</p><p>Compared with immediate ICU admission, later ICU admission was not associated with hospital mortality. Clinical respiratory events were independently associated with both later ICU admission and hospital mortality.</p></div
Characteristics of initially not admitted patients according to hospital mortality.
<p>Characteristics of initially not admitted patients according to hospital mortality.</p
Flow chart.
<p><sup>1</sup> Multiple requests for a same patient: only the first was analysed. <sup>2</sup> Multiple ICU stays for a same patient: only the first was analysed.</p
Characteristics of ICU stay for « immediate admission » and « late admission » groups.
<p>Characteristics of ICU stay for « immediate admission » and « late admission » groups.</p
Reasons for ICU requests among initially not admitted patients.
<p>Reasons for ICU requests among initially not admitted patients.</p
Kaplan-Meier survival curves of « immediate admission » and « later admission » groups.
<p>Kaplan-Meier survival curves of « immediate admission » and « later admission » groups.</p
Factors associated with a later ICU admission among initially not admitted patients.
<p>Factors associated with a later ICU admission among initially not admitted patients.</p
Kaplan-Meier survival curves of patients presenting a respiratory event and no respiratory event.
<p>Kaplan-Meier survival curves of patients presenting a respiratory event and no respiratory event.</p