37 research outputs found
Renal arterial aneurysm--an incidental finding at autopsy.
Herein we describe a rare case of saccular renal artery aneurysm seen as an incidental autopsy finding in an elderly, hypertensive female. The aneurysm was seen as a small exophytic mass with calcified wall and lumen occluded by recanalized thrombus
Letter to the Editor - Heterotopic Uterine Cartilage
Sir, We report herewith a rare case of heterotopic uterine cartilage.
A 45-year-old gravida six, para six female underwent hysterectomy for
complaints of menorrhagia. The uterus showed a 2cm circumscribed
translucent nodule located in the endometrial lining just above the
uterine isthmus (Figure). The nodule could be shelled out from the
adjacent tissue. Microscopy revealed a lobule of benign hyaline
cartilage positioned between the endometrial lining and the myometrium.
There was a cleavage plane between the cartilage and adjacent tissue.
However, the cartilage edges focally showed presence of endometrial
stromal cells. There was no inflammation or tumour and no other tissue
was identified. A diagnosis of benign heterotopic uterine cartilage was
made
Letter to the Editor - Heterotopic Uterine Cartilage
Sir, We report herewith a rare case of heterotopic uterine cartilage.
A 45-year-old gravida six, para six female underwent hysterectomy for
complaints of menorrhagia. The uterus showed a 2cm circumscribed
translucent nodule located in the endometrial lining just above the
uterine isthmus (Figure). The nodule could be shelled out from the
adjacent tissue. Microscopy revealed a lobule of benign hyaline
cartilage positioned between the endometrial lining and the myometrium.
There was a cleavage plane between the cartilage and adjacent tissue.
However, the cartilage edges focally showed presence of endometrial
stromal cells. There was no inflammation or tumour and no other tissue
was identified. A diagnosis of benign heterotopic uterine cartilage was
made
Tuberculosis of the renal artery.
A young female who underwent nephrectomy for renovascular hypertension was diagnosed on histology to have tuberculosis of the renal artery. This was an isolated finding as there was no tuberculous infection elsewhere including tissues in the vicinity of the vessels. A survey of literature did not yield any reports of tuberculous renal arteritis, making this the first such case
Recurrence of primary hyperoxaluria: An avoidable catastrophe following kidney transplant
Primary hyperoxaluria is a rare autosomal recessive disease due to deficiency of an oxalate-metabolizing liver enzyme, which results in nephrolithiasis and renal failure. Concomitant liver and kidney transplant is recommended as isolated kidney transplant is inevitably complicated by recurrence of the disease. We present a 25-year-old man with end-stage nephrolithiatic renal disease who underwent bilateral nephrectomy, followed by kidney transplantation. There was progressive worsening of kidney function two weeks post transplant. Review of nephrectomy and transplant kidney biopsy showed abundant calcium oxalate crystals and further workup revealed hyperoxaluria, which was previously unsuspected. Later he developed fever, breathlessness, hemiparesis and died 10 weeks after transplant. Autopsy revealed multi-organ deposits of oxalate crystals as well as widespread zygomycosis. This case emphasizes the need for careful pre-transplant evaluation of patients with renal calculus disease in order to exclude primary hyperoxaluria
Recurrence of primary hyperoxaluria: An avoidable catastrophe following kidney transplant
Primary hyperoxaluria is a rare autosomal recessive disease due to
deficiency of an oxalate-metabolizing liver enzyme, which results in
nephrolithiasis and renal failure. Concomitant liver and kidney
transplant is recommended as isolated kidney transplant is inevitably
complicated by recurrence of the disease. We present a 25-year-old man
with end-stage nephrolithiatic renal disease who underwent bilateral
nephrectomy, followed by kidney transplantation. There was progressive
worsening of kidney function two weeks post transplant. Review of
nephrectomy and transplant kidney biopsy showed abundant calcium
oxalate crystals and further workup revealed hyperoxaluria, which was
previously unsuspected. Later he developed fever, breathlessness,
hemiparesis and died 10 weeks after transplant. Autopsy revealed
multi-organ deposits of oxalate crystals as well as widespread
zygomycosis. This case emphasizes the need for careful pre-transplant
evaluation of patients with renal calculus disease in order to exclude
primary hyperoxaluria