306 research outputs found
SMALL FARMS IN AMERICA--THE DIVERSITY OF PROBLEMS AND SOLUTIONS
Agricultural and Food Policy,
POLICY OPTIONS FOR A MORE SUSTAINABLE AGRICULTURE
Agricultural and Food Policy,
A Delay-Discounting Primer
Given the importance of research findings and the potential of further research to aid in the prediction and control of impulsivity, the primary focus of this chapter (and this book) is on choice and the failure of future events to affect current decisions. In this primer chapter, we consider two types of impulsive choice: (a) preferring a smaller-sooner reward while forgoing a larger-later one and (b) preferring a larger-later aversive outcome over a smaller-sooner one. The first of these is exemplified by the toy-pilfering child with whom we opened this chapter. Taking the toy is immediately rewarded, but it is a short-lived reward because the caretaker soon returns the toy to the victimized peer. Undoubtedly, the child would prefer to play with the toy for a longer period of time, but waiting until the toy is dropped by the peer seems a weak reinforcer when compared with brief access now. To put an economic term on this phenomenon, the child appears to have discounted the value of the delayed but otherwise preferred reward. Delay discounting describes the process of devaluing behavioral outcomes, be they rewarding or aversive events, that happen in the future (and perhaps the past; see chap. 7, this volume). This chapter provides a primer in delay discounting; it is intended for readers who have only a limited background in the procedures, measures, and outcomes of studies examining this form of impulsive choice. Following an overview of the delay-discounting process, its quantification, and its implications for the human condition, emphasis is placed on procedures (and critiques of these procedures). The remainder of the book is concerned with experimental findings, and for the most part, we do not review these here
Milk production functions in relation to feed inputs, cow characteristics and environmental conditions
The main emphasis of this study is on milk production functions as they relate to various levels and proportions of grain and hay in a ration restricted to these two feeds. However, certain auxiliary variables representing cow characteristics and environmental conditions are also incorporated into the production function. The auxiliary variables include: stage of lactation, milk-producing ability, temperature, age, maturity, body weight and a coefficient of inbreeding. These auxiliary variables are fixed at different levels to allow expression of milk production functions when the characteristics of cows are set at different magnitudes.
This study considers the economic optima in ration specification for dairy cows and represents a cooperative interdisciplinary effort. The estimates allow derivation of production surfaces, milk isoclines and isoquants, marginal rates of feed substitution and profit-maximizing rations for cows of different characteristics (maturity, ability, inbreeding, weight) producing under specified environmental conditions
Effects of Pramipexole on Impulsive Choice in Male Wistar Rats
This article may not exactly replicate the final version published in the APA journal. It is not the copy of record.Clinical reports, primarily with Parkinson’s patients, note an association between the prescribed use of pramipexole (and other direct-acting dopamine agonist medications) and impulse control disorders, particularly pathological gambling. Two experiments examined the effects of acute pramipexole on rats’ impulsive choices where impulsivity was defined as selecting a smaller-sooner over a larger-later food reward. In Experiment 1, pramipexole (0.1 to 0.3 mg/kg) significantly increased impulsive choices in a condition in which few impulsive choices were made during a stable baseline. In a control condition, in which impulsive choices predominated during baseline, pramipexole did not significantly change the same rats’ choices. Experiment 2 explored a wider range of doses (0.01 to 0.3 mg/kg) using a choice procedure in which delays to the larger-later reinforcer delivery increased across trial blocks within each session. At the doses used in Experiment 1, pramipexole shifted choice toward indifference regardless of the operative delay. At lower doses of pramipexole (0.01 & 0.03 mg/kg), a trend toward more impulsive choice was observed at the 0.03 mg/kg dose. The difference in outcomes across experiments may be due to the more complex discriminations required in Experiment 2; i.e., multiple discriminations between changing delays within each session
Efficacy of Fluoroquinolone/Probiotic Combination Therapy for Recurrent Urinary Tract Infection in Children: A Retrospective Analysis
AbstractPurposeChildren with normal urinary tract anatomy and function and highly recurrent urinary tract infection (rUTI) may have a lack of alternatives when antibiotic prophylaxis and "watchful waiting" approaches fail. This retrospective review reports the outcomes in children who received a fluoroquinolone/probiotic combination in an attempt to quantify a reduction in rUTI that was perceived by both clinicians and patients' families.MethodsData from all children with rUTIs previously managed with a fluoroquinolone/probiotic combination at the Pediatric Infectious Diseases Clinic at Duke University Medical Center (Durham, North Carolina) were identified and analyzed.FindingsData from 10 children were eligible for inclusion. Compared with before therapy initiation, total UTI episodes were significantly fewer after therapy initiation (57 vs 4; P = 0.0001). Seven (70%) were free of rUTIs during the follow-up period. Of the 8 patients with known compliance, 7 (88%) were free of rUTIs.ImplicationsGiven the chronic nature of these patients' symptoms, the significant decrease in UTI after the initiation of therapy, and the increase in the interval without an infection and/or its symptoms, this treatment regimen has the potential to improve overall quality of life, decrease antibiotic courses, and decrease health care costs in children with rUTI. These results will be validated with a larger cohort of patients in a prospective, randomized trial
Warm H as a probe of massive accretion and feedback through shocks and turbulence across cosmic time
Galaxy formation depends on a complex interplay between gravitational
collapse, gas accretion, merging, and feedback processes. Yet, after many
decades of investigation, these concepts are poorly understood. This paper
presents the argument that warm H can be used as a tool to unlock some of
these mysteries. Turbulence, shocks and outflows, driven by star formation, AGN
activity or inflows, may prevent the rapid buildup of star formation in
galaxies. Central to our understanding of how gas is converted into stars is
the process by which gas can dissipate its mechanical energy through turbulence
and shocks in order to cool. H lines provide direct quantitative
measurements of kinetic energy dissipation in molecular gas in galaxies
throughout the Universe. Based on the detection of very powerful H lines
from z = 2 galaxies and proto-clusters at the detection limits of {\it
Spitzer}, we are confident that future far-IR and UV H observations will
provide a wealth of new information and insight into galaxy evolution to
high-z. Finally, at the very earliest epoch of star and galaxy formation, warm
H may also provide a unique glimpse of molecular gas collapse at 7 z
12 in massive dark matter (DM) halos on their way to forming the very first
galaxies. Such measurements are beyond the reach of existing and planned
observatories.Comment: Submitted as a science White Paper to the Astronomy and Astrophysics
Astro 2020 Decadal Survey call issued by the National Academies of Sciences,
Engineering and Medicine (March 11 2019
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Recommendations for Effective Integration of Ethics and Responsible Conduct of Research (E/RCR) Education into Course-Based Undergraduate Research Experiences: A Meeting Report.
Advancement of the scientific enterprise relies on individuals conducting research in an ethical and responsible manner. Educating emergent scholars in the principles of ethics/responsible conduct of research (E/RCR) is therefore critical to ensuring such advancement. The recent impetus to include authentic research opportunities as part of the undergraduate curriculum, via course-based undergraduate research experiences (CUREs), has been shown to increase cognitive and noncognitive student outcomes. Because of these important benefits, CUREs are becoming more common and often constitute the first research experience for many students. However, despite the importance of E/RCR in the research process, we know of few efforts to incorporate E/RCR education into CUREs. The Ethics Network for Course-based Opportunities in Undergraduate Research (ENCOUR) was created to address this concern and promote the integration of E/RCR within CUREs in the biological sciences and related disciplines. During the inaugural ENCOUR meeting, a four-pronged approach was used to develop guidelines for the effective integration of E/RCR in CUREs. This approach included: 1) defining appropriate student learning objectives; 2) identifying relevant curriculum; 3) identifying relevant assessments; and 4) defining key aspects of professional development for CURE facilitators. Meeting outcomes, including the aforementioned E/RCR guidelines, are described herein
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