Studi Penjaminan Mutu (Quality Assurance) Internal Dalam Pelayanan Kefarmasian

Pharmaceutical services in hospitals aim to improve the quality of pharmaceutical services, protect patients from irrational drug use to maintain patient safety, and ensure legal certainty for pharmacists. Quality Assurance (QA) is used in measuring service quality, whereas QA in IFRS aims to provide assurance of product quality and the quality of pharmaceutical services provided to patients. This research employs descriptive research with a cross-sectional method, and primary date are obtained from questionnaires with the framework of QA standard indicators in pharmaceutical services at the primary Installastion of Mother and Child Hospital Kasih Fatimah Kotamobagu, with five respondents. The results indicate that internal quality assurance in pharmaceutical services at the Fatimah Kotamobagu Mother and Child Hospital Kasih Fatimah Kotamobagu Pharmacy Installation was in accordance with quality assurance standards, especially in the aspects of organizational structure, quality measures, and safety assurance, as well as drug distribution with an overall value in the criteria, are (75%), moderately appropriate are (15%) and not appropriate are (10%)

Tingkat Pengetahuan Masyarakat Terhadap Tindakan Penggunaan Antibiotik Tanpa Resep Dokter

Antibiotics is a subtance that can kill or weaken an organism such as bacteria, parasite, or fungi.  The use of antibiotics always triggers a problem, such as the use of it without any medical prescription. It sometimes happens caused by some factors such as the lack of people’s knowledge concerning the consumption of antibiotics. This research aims at investigating the correlation between the respondent’s characteristics toward knowledge, attitude, and action. Also, it is to investigate the correlation between knowledge and attitude toward the consumption of antibiotics without medical prescription. The research design applies analytical observation with cross sectional approach. The research subjects are 96 respondents selected by purposive sampling technique. The research instrument is questionnaires consisting of questionnaire of knowledge, attitude, and action. The method of data analysis is multiple correlation. Findings reveal that the people’s level of knowledge is still low obtaining 47,7% of score, the people’s attitude is categorized negative (supporting the consumption of antibiotics without medical) obtaining 54,2%, the people’s action categorized not appropriate obtaining 57,3%, there is correlation between education and job toward knowledge, attitude, and action (p0,05), there is no correlation between age and sex toward knowledge, attitude, and action (p0,05), and there is a correlation between knowledge and attitude toward action (p=0,000)

Polarized Growth in the Absence of F-Actin in Saccharomyces cerevisiae Exiting Quiescence

Polarity establishment and maintenance are crucial for morphogenesis and development. In budding yeast, these two intricate processes involve the superposition of regulatory loops between polarity landmarks, RHO GTPases, actin-mediated vesicles transport and endocytosis. Deciphering the chronology and the significance of each molecular step of polarized growth is therefore very challenging.We have taken advantage of the fact that yeast quiescent cells display actin bodies, a non polarized actin structure, to evaluate the role of F-actin in bud emergence. Here we show that upon exit from quiescence, actin cables are not required for the first steps of polarized growth. We further show that polarized growth can occur in the absence of actin patch-mediated endocytosis. We finally establish, using latrunculin-A, that the first steps of polarized growth do not require any F-actin containing structures. Yet, these structures are required for the formation of a bona fide daughter cell and cell cycle completion. We propose that upon exit from quiescence in the absence of F-actin, secretory vesicles randomly reach the plasma membrane but preferentially dock and fuse where polarity cues are localized, this being sufficient to trigger polarized growth