A fully-coherent all-sky search for gravitational-waves from compact binary coalescences

We introduce a fully-coherent method for searching for gravitational wave signals generated by the merger of black hole and/or neutron star binaries. This extends the coherent analysis previously developed and used for targeted gravitational wave searches to an all-sky, all-time search. We apply the search to one month of data taken during the fifth science run of the LIGO detectors. We demonstrate an increase in sensitivity of 25% over the coincidence search, which is commensurate with expectations. Finally, we discuss prospects for implementing and running a coherent search for gravitational wave signals from binary coalescence in the advanced gravitational wave detector data.Comment: 17 pages, 12 figure

Stressed Skin Design of Steel Sheeting Panels – Part 2: Shear Panels with Sheeting Fixed on all 4 Sides

In this paper, the strength and stiffness of different roof panels were investigated, in order to establish their ability to act as in-plane diaphragms for stressed skin design of cold-formed steel portal frames. A total of 6 roof panels, approximately 3 x 3m, were examined by testing with sheeting profiles fixed on 4 sides. A variety of sheeting profiles in two industry standard thicknesses of 0.5 and 0.7mm were tested, all using top-hat shaped purlins fixed with self-drilling, self-tapping screws. The experimental strength and stiffness of each panel were then compared against existing design methods. The Finite Element Analysis (FEA) modelling techniques were also presented and validated against series of full-scale tests. The FEA results have shown that the ‘true’ level of loading transferred via shear connector screws was on average 13% lower than that assumed by standard design methods. On the contrary, seam connections failure, according to FEA results, have governed a design in all of the analysed cases and the analytical method overestimated shear resistances of the panels by 45% and 35% in case of 0.5mm and 0.7mm thick sheeting profiles respectively. It was demonstrated that FEA results have represented the upper bound of experimental shear stiffness, with a very close prediction for 0.5mm thick sheeting profiles. Overall all, the tested panels demonstrated an average 41% greater flexibility then this predicted using FEA models

Stressed Skin Design of Steel Sheeting Panels – Part 1: Shear Resistance and Flexibility of Screw Lapped Joists

The shear resistance and flexibility of a steel roof diaphragm depend largely on shear resistance and slip flexibility of the single screw lap joint. In this paper, screw connections relevant to modern roof construction are investigated. The tests provided experimental values of shear/tearing resistance and joint flexibility of seam connections, cladding/purlin connections and purlin/rafter connections. The novel aspects of the experimental research include investigation of the behaviour of shear connections in 0.5mm thick sheeting and thick-to-thin connections in S550 high tensile steel. Overall, six series of tests were conducted and each test was repeated five times in order to demonstrate a scatter of test results. Test results were examined against existing semi-empirical formulas for predicting the shear resistance of screw joints. It was demonstrated that the design equation presented by Toma et al. (1993), without the additional condition included in Eurocode 3, offers the closest prediction in terms of joint shear resistance. In terms of joint flexibility, it was demonstrated that existing formulas developed for bolted connection (Zadanfarrokh and Bryan (1992) and Dubina and Zaharia (2006)) can be successfully used for screw connections. The flexibility reduction factor npf=0.4 was also proposed to take account of perfect fit screw connections

Hadronic interactions, precocious unification, and cosmic ray showers at Auger energies

At Auger energies only model predictions enable us to extract primary cosmic ray features. The simulation of the shower evolution depends sensitively on the first few interactions, necessarily related to the quality of our understanding of high energy hadronic collisions. Distortions of the standard ``soft semi-hard'' scenario include novel large compact dimensions and a string or quantum gravity scale not far above the electroweak scale. Na\"{\i}vely, the additional degrees of freedom yield unification of all forces in the TeV range. In this article we study the influence of such precocious unification during atmospheric cascade developments by analyzing the most relevant observables in proton induced showers.Comment: 16 pages latex. 4 eps figure

Effects of alternative uses of distillery by-products on the greenhouse gas emissions of Scottish malt whisky production: a system expansion approach

Agricultural by-products are an important component of livestock feed. In Scotland, distillery by-products are protein rich and traditionally cost competitive feed ingredients in cattle production. However, during recent years, distilleries in the UK (including Scotch whisky producers) have started to use the by-products also as a source of renewable energy, in order to reduce the carbon footprint of alcohol production. In this study, a systems-based material and energy flow analysis was performed to calculate the life-cycle greenhouse gas (GHG) emissions of whisky production for two scenarios where distillery by-products were used either (1) as beef cattle feed to replace other protein sources (namely soya bean meal and rapeseed meal); or (2) as anaerobic digester (AD) feedstock in order to generate renewable energy (heat and electricity). System expansion was used to quantitatively handle the by-products in the analysis. The results show that considerable reductions in GHG emissions could be achieved by either replacing feed crops with by-products or by using the by-products in AD plants to generate bio-energy. The biggest reductions in the GHG emissions were achieved when by-products were used to replace soya meal in animal feed. However, the results are highly sensitive to methodological choices, including the accounting method of the land use change emissions arising from soya production

Optical properties of atomic Mott insulators: from slow light to dynamical Casimir effects

We theoretically study the optical properties of a gas of ultracold, coherently dressed three-level atoms in a Mott insulator phase of an optical lattice. The vacuum state, the band dispersion and the absorption spectrum of the polariton field can be controlled in real time by varying the amplitude and the frequency of the dressing beam. In the weak dressing regime, the system shows unique ultra-slow light propagation properties without absorption. In the presence of a fast time modulation of the dressing amplitude, we predict a significant emission of photon pairs by parametric amplification of the polaritonic zero-point fluctuations. Quantitative considerations on the experimental observability of such a dynamical Casimir effect are presented for the most promising atomic species and level schemes

Systematic review and meta-analysis of temozolomide in animal models of glioma:was clinical efficacy predicted?

Background:Malignant glioma is an aggressive tumour commonly associated with a dismal outcome despite optimal surgical and radio-chemotherapy. Since 2005 temozolomide has been established as first-line chemotherapy. We investigate the role of in vivo glioma models in predicting clinical efficacy.Methods:We searched three online databases to systematically identify publications testing temozolomide in animal models of glioma. Median survival and number of animals treated were extracted and quality was assessed using a 12-point scale; random effects meta-analysis was used to estimate efficacy. We analysed the impact of study design and quality and looked for evidence of publication bias.Results:We identified 60 publications using temozolomide in models of glioma, comprising 2443 animals. Temozolomide prolonged survival by a factor of 1.88 (95% CI 1.74-2.03) and reduced tumour volume by 50.4% (41.8-58.9) compared with untreated controls. Study design characteristics accounted for a significant proportion of between-study heterogeneity, and there was evidence of a significant publication bias.Conclusion:These data reflect those from clinical trials in that temozolomide improves survival and reduces tumour volume, even after accounting for publication bias. Experimental in vivo glioma studies of temozolomide differ from those of other glioma therapies in their consistent efficacy and successful translation into clinical medicine

Thallium under extreme compression

We present a combined theoretical and experimental study of the high-pressure behavior of thallium. X-ray diffraction experiments have been carried out at room temperature up to 125 GPa using diamond-anvil cells, nearly doubling the pressure range of previous experiments. We have confirmed the hcp-fcc transition at 3.5 GPa and determined that the fcc structure remains stable up to the highest pressure attained in the experiments. In addition, HP-HT experiments have been performed up to 8 GPa and 700 K by using a combination of x-ray diffraction and a resistively heated diamond-anvil cell. Information on the phase boundaries is obtained, as well as crystallographic information on the HT bcc phase. The equation of state for different phases is reported. Ab initio calculations have also been carried out considering several potential high-pressure structures. They are consistent with the experimental results and predict that, among the structures considered in the calculations, the fcc structure of thallium is stable up to 4.3 TPa. Calculations also predict the post-fcc phase to have a close-packed orthorhombic structure above 4.3 TPa.Comment: 29 pages, 14 figure