21 research outputs found

    Marital interaction theory: some implications for research

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    This project examines specific basic areas of marital interaction theory. Individual chapters are developed around the following themes: historical development of the theory of interaction; a theoretical discussion of selected concepts; personality as a determinant of interaction; communication in marriage; marital interaction patterns; methodology pertaining to research findings; and finally some implications for research which became apparent as this project developed. The project lays the conceptual groundwork for a series of empirical studies that will use the interactional approach as a theoretical base. The immediate purpose of this project therefore is to describe the important dimensions of the interactional approach as these pertain to marital interaction. Interaction is defined as a reciprocal relationship in which each person may produce effects upon the other. Here the essence of marriage is interaction; thus marital interaction is critical in its effect on the spouses and the continuity of the marriage. Some of the basic concepts of George Mead are described and it is suggested that they are essential elements of the interactional approach. The major assumptions of this approach are that a) human behavior cannot be derived or inferred from nonhuman forms, b) the social act is the primary analytic unit for an understanding of society and the personality, c) the human infant is potentially social, and d) the human being is actor as well as reactor. Personality is discussed as a determinant of the quality and quantity of marital interaction. The issue of personal competence is explored, particularly in respect to verbal ability. Communication, the process of influence, is defined for marital interaction and the consequent formation of patterns. Identification and classification of marital interaction patterns are limited to a description of selected examples from family research and the observations of clinicians. Patterns tend to be defined in psychological terms although communicative behavior is stressed. The absence of common criteria and terminology is noted. Description of dysfunctional patterns predominates. Two methods frequently used in recent studies of marital interaction are direct observation and analysis of reports from marital partners. It is suggested that a combination of these techniques could increase the quantity of information about marital interaction. Research questions focus on the problem of adult socialization, its implications for the establishment of marital interaction patterns, and the need to determine the relation between the interaction process and the functional or dysfunctional quality of the resultant pattern. An inseparable part of the aforementioned research areas is the function of communication. It is suggested that investigation of verbal communication might yield significant data for the understanding of the interaction process as it affects the personalities of the spouses and the formation of patterns

    Tenascin C interacts with Ecto-5â€Č-nucleotidase (eN) and regulates adenosine generation in cancer cells

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    Tenascin C is expressed in invasive human solid tumors; however its specific role in cancer biology remains obscure. Previously, we have found that ecto-5'-nucleotidase (eN) is a marker of ER (-) breast carcinoma and elevated expression correlates with invasive mesenchymal cell phenotype. To investigate for the potential relationship between eN and protein components of the extracellular matrix (ECM) we measured adenosine generation from AMP in cells incubated with soluble ECM proteins. We found that tenascin C was the only ECM component that strongly inhibited ecto-5'-nucleotidase (eN) activity in situ and adenosine generation from AMP (75% inhibition, p < 0.01). The inhibition was comparable to that induced by concanavalin A, a well-defined and strong inhibitor of eN. Resin immobilized tenascin C, but not collagen, and only weakly fibronectin, specifically and quantitatively bound cell-extracted eN. We further developed breast cancer cell line with reduced eN expression and tested changes in cell adhesion on different ECM. Breast cancer cells expressing reduced eN attached 56% weaker (p < 0.05) to immobilized tenascin C. This difference was not detected with other ECM proteins. Finally, control breast cancer cells migrated slower on tenascin C when compared with clone with reduced eN expression. These data suggest that eN is a novel and specific receptor for tenascin C and that the interaction between these proteins may influence cell adhesion and migration and also lead to decreased generation of local adenosine

    Trapping \u3ci\u3ePhyllophaga \u3c/i\u3espp. (Coleoptera: Scarabaeidae: Melolonthinae) in the United States and Canada using sex attractants.

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    The sex pheromone of the scarab beetle, Phyllophaga anxia, is a blend of the methyl esters of two amino acids, L-valine and L-isoleucine. A field trapping study was conducted, deploying different blends of the two compounds at 59 locations in the United States and Canada. More than 57,000 males of 61 Phyllophaga species (Coleoptera: Scarabaeidae: Melolonthinae) were captured and identified. Three major findings included: (1) widespread use of the two compounds [of the 147 Phyllophaga (sensu stricto) species found in the United States and Canada, males of nearly 40% were captured]; (2) in most species intraspecific male response to the pheromone blends was stable between years and over geography; and (3) an unusual pheromone polymorphism was described from P. anxia. Populations at some locations were captured with L-valine methyl ester alone, whereas populations at other locations were captured with L-isoleucine methyl ester alone. At additional locations, the L-valine methyl ester-responding populations and the L-isoleucine methyl ester-responding populations were both present, producing a bimodal capture curve. In southeastern Massachusetts and in Rhode Island, in the United States, P. anxia males were captured with blends of L-valine methyl ester and L-isoleucine methyl ester

    Adapting obstetric and neonatal services during the COVID-19 pandemic: a scoping review

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    Abstract Background The provision of care to pregnant persons and neonates must continue through pandemics. To maintain quality of care, while minimizing physical contact during the Severe Acute Respiratory Syndrome-related Coronavirus-2 (SARS-CoV2) pandemic, hospitals and international organizations issued recommendations on maternity and neonatal care delivery and restructuring of clinical and academic services. Early in the pandemic, recommendations relied on expert opinion, and offered a one-size-fits-all set of guidelines. Our aim was to examine these recommendations and provide the rationale and context to guide clinicians, administrators, educators, and researchers, on how to adapt maternity and neonatal services during the pandemic, regardless of jurisdiction. Method Our initial database search used Medical subject headings and free-text search terms related to coronavirus infections, pregnancy and neonatology, and summarized relevant recommendations from international society guidelines. Subsequent targeted searches to December 30, 2020, included relevant publications in general medical and obstetric journals, and updated society recommendations. Results We identified 846 titles and abstracts, of which 105 English-language publications fulfilled eligibility criteria and were included in our study. A multidisciplinary team representing clinicians from various disciplines, academics, administrators and training program directors critically appraised the literature to collate recommendations by multiple jurisdictions, including a quaternary care Canadian hospital, to provide context and rationale for viable options. Interpretation There are different schools of thought regarding effective practices in obstetric and neonatal services. Our critical review presents the rationale to effectively modify services, based on the phase of the pandemic, the prevalence of infection in the population, and resource availability
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