Contemporary Christian radio in Britain: A new genre on the national dial

Only in the second decade of the twenty-first century has contemporary Christian radio appeared as a new genre in Britain, unlike the United States where it has long been a significant format. Responsibility for religious broadcasting in the United Kingdom was, for most of the twentieth century, fulfilled by the BBC. However, the gradual relaxation of broadcasting regulations since the 1980s and the introduction of Digital Audio Broadcasting (DAB) have provided openings for Christian radio stations, and since 2009 the United Kingdom has had two national stations broadcasting from mainland studios for the first time. This article explores recent developments in this genre, using primary research interviews with Christian radio broadcasters. It suggests that what started out as a way for Christians to evangelize and proselytize their message has become a radio service that broadcasts almost exclusively to converted believers. It also observes that the programming and scheduling of these stations closely resembles the speech-and-music-mix style of BBC Local Radio, implying an attempt to insert themselves directly into the mainstream of the radio spectrum

Deep sequencing of Phox2a nuclei reveals five classes of anterolateral system neurons

The anterolateral system (ALS) is a major ascending pathway from the spinal cord that projects to multiple brain areas and underlies the perception of pain, itch, and skin temperature. Despite its importance, our understanding of this system has been hampered by the considerable functional and molecular diversity of its constituent cells. Here, we use fluorescence-activated cell sorting to isolate ALS neurons belonging to the Phox2a-lineage for single-nucleus RNA sequencing. We reveal five distinct clusters of ALS neurons (ALS1-5) and document their laminar distribution in the spinal cord using in situ hybridization. We identify three clusters of neurons located predominantly in laminae I–III of the dorsal horn (ALS1-3) and two clusters with cell bodies located in deeper laminae (ALS4 and ALS5). Our findings reveal the transcriptional logic that underlies ALS neuronal diversity in the adult mouse and uncover the molecular identity of two previously identified classes of projection neurons. We also show that these molecular signatures can be used to target groups of ALS neurons using retrograde viral tracing. Overall, our findings provide a valuable resource for studying somatosensory biology and targeting subclasses of ALS neurons