Results of HLM for FFA scores against age, sex, BMI, genetic ancestry and PC scores for wealth index.

<p>For simplicity, and considering the high correlation between both data sets, results are presented only for heterozygosity-corrected data (blue-colored cells indicate significant effects at p< = 0.01).</p

Boxplots of distribution of the FFA scores by country and sex.

<p>The dotted line represents the grand mean, the continuous black line connect means among countries. a) Females, b) males. Black points represent outlier values. The left column plots represent raw FFA scores and the right ones the FFA scores corrected for the heterozygosity effects.</p

Facial landmark anatomical definitions (see Fig 1 for anatomic-spatial reference).

<p>Facial landmark anatomical definitions (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0169287#pone.0169287.g001" target="_blank">Fig 1</a> for anatomic-spatial reference).</p

Sample details concerning age, gender and country for a total of 2,018 volunteers.

<p>Sample details concerning age, gender and country for a total of 2,018 volunteers.</p

Anatomical location of the 34 landmarks used in this study depicted on a fronto-lateral view of the face (see Table 2 for definitions).

<p>According to the ethic approval and written informed consent of CANDELA Project, pictures of volunteers cannot be provided in scientific publications or websites. The image presented here belongs to a collaborator who has given written informed consent (as outlined in PLOS consent form) to publish this figure, and was taken following the standard CANDELA protocols.</p

Matrix depicting correlations among wide-genome heterozygosity scores and genetic ancestry estimations.

<p>a) Males, b) Females. Ellipses account for the 95% of the variance and the color depicts the r-value magnitude (see right-bottom scale for reference). The corresponding r-values are placed in the lower triangle of the matrix.</p

Repeatability essay: Procrustes ANOVA results with sex as covariate.

<p>Repeatability essay: Procrustes ANOVA results with sex as covariate.</p

Inter- and intraobserver mean errors across three digitizing sessions (February, January and December).

<p>RMSE = Root of the mean square error (see text for details).</p

Central tendency and dispersal statistics for within and between-observer differences.

<p>Central tendency and dispersal statistics for within and between-observer differences.</p

Matrix of correlation of FFA scores (corrected and uncorrected for heterozygosity effects) against SES variables (PCA-WI) by sex.

<p>a) Females b) Males. Raw and corrected FFA scores are presented in the left and right columns respectively. Ellipses account for the 95% of the variance and the color depicts the r-value magnitude (see left-bottom scale for reference). Lower triangle of the matrix indicates the r-value correlation scores.</p