6,551 research outputs found
Myths and lessons of liberal intervention: The British campaign for the abolition of the Atlantic slave trade to Brazil
This is the Pre-print version of the Article. The official published version can be accessed from the link below - Copyright @ 2012 Martinus NijhoffThis article takes issue with recent references to the British nineteenth century campaign for the abolition of the trans-Atlantic slave trade to Brazil that serve to bolster interventionist or imperialist agendas. In particular, such accounts reproduce two and a half myths about the campaign: that it can serve as a model for the present age; that the success of the campaign can be explained through the actions of the intervening party alone (with a corresponding neglect of those of the ātargetā state); and the half-myth that the campaignās success was due to military action (at the expense of institutional (legal) and normative factors and the capacity of the target state). I argue instead that this case ā and interventions more generally ā would benefit from an analysis that considers the role of force in relation to a series of residual institutional and cultural constraints within the liberal state and to political conditions in the target state. In light of the complexities and contingencies that these factors present the underlying lesson is that military force should be used sparingly, if at all
Ex Ante Benefit Cost Analysis Of Small Farm Maize Research And Demonstrations, Zimbabwe
AEE Working paper.With the increasing scarcity of public funds for agricultural research - agricultural research as a percentage of GDP is falling - pressure is being placed on research managers to justify their expenditures, Budget reductions are resulting in reduced farm demonstrations and inappropriate combinations of researchers/technicians. The research strategy of "yield and quality" has been successful for many agricultural research institutes in the past. Improved performance of agricultural research institutes can be achieved by selecting alternative research programs and projects using benefit/cost (B/C) criteria.
Ex ante benefit/cost analysis can be used as an investment criterion to select research and demonstration activities with potentially high investment returns. Ex post or historical investment analysis is useful but is not directly relevant for identifying current high pay-off research projects and programs. The ex ante benefit measure focuses on improvements in future farm financial gross margins for small farmers resulting from current research/and demonstration activities. The time, travel and other costs associated with a given research and demonstration activity by agricultural researchers and extension staff are considered as a capital investment cost: on an incremental project basis
Adenosine to inosine editing by ADAR2 requires formation of a ternary complex on the GluR-B R/G site
RNA editing by members of the ADAR (adenosine deaminase that acts on RNA) enzyme family involves hydrolytic deamination of adenosine to inosine within the context of a double-stranded pre-mRNA substrate. Editing of the human GluR-B transcript is catalyzed by, the enzyme ADAR2 at the Q/R and R/G sites. We have established a minimal RNA substrate for editing based on the RIG site and have characterized the interaction of ADAR2 with this RNA by gel shift, kinetic, and cross-linking analyses. Gel shift analysis revealed that two complexes are formed on the RNA as protein concentration is increased; the ADAR monomers can be crosslinked to one another in an RNA-dependent fashion. We performed a detailed kinetic study of the editing reaction; the data from this study are consistent with a reaction scheme in which formation of an ADAR2.RNA ternary complex is required for efficient RNA editing and in which formation of this complex is rate determining. These observations suggest that RNA adenosine deaminases function as homodimers on their RNA substrates and may partially explain regulation of RNA editing in these systems
First schizophrenic illness: presentation and short term outcome, incorporating a trial of prophylactic neuroleptic maintenance therapy versus placebo
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Income Inequality, Intergenerational Mobility, and the Great Gatsby Curve: Is Education the Key?
It is widely believed that countries with greater levels of income inequality also have lower levels of intergenerational mobility. This relationship, known as the Great Gatsby Curve (GGC), has been prominently cited by high-ranking public policymakers, bestselling authors, and Nobel Prizeāwinning academics. Yet, relatively little crossnational work has empirically examined the mechanisms thought to underpin the GGCāparticularly with regard to the role of educational attainment. This paper uses the cross-nationally comparable Programme for International Assessment of Adult Competencies (PIAAC) data set to shed new light on this issue. We find that income inequality is associated with several key components of the intergenerational transmission
processāincluding access to higher education, the financial returns on education, and the residual effect of parental education upon labor-market earnings. Thus, consistent with theoretical models, we find that educational attainment is an important driver of the relationship between intergenerational mobility and income inequality. We hence conclude that unequal access to financial resources plays a central role in the
intergenerational transmission of advantage
A serological survey of ruminant livestock in Kazakhstan during post-Soviet transitions in farming and disease control
The results of a serological survey of livestock in Kazakhstan, carried out in 1997ā1998, are reported. Serum samples from 958 animals (cattle, sheep and goats) were tested for antibodies to foot and mouth disease (FMD), bluetongue (BT), epizootic haemorrhagic disease (EHD), rinderpest (RP) and peste des petits ruminants (PPR) viruses, and to Brucella spp. We also investigated the vaccination status of livestock and related this to changes in veterinary provision since independence in 1991. For the 2 diseases under official surveillance (FMD and brucellosis) our results were similar to official data, although we found significantly higher brucellosis levels in 2 districts and widespread ignorance about FMD vaccination status. The seroprevalence for BT virus was 23%, and seropositive animals were widespread suggesting endemicity, despite the disease not having being previously reported. We found a few seropositives for EHDV and PPRV, which may suggest that these diseases are also present in Kazakhstan. An hierarchical model showed that seroprevalence to FMD and BT viruses were clustered at the farm/village level, rather than at a larger spatial scale. This was unexpected for FMD, which is subject to vaccination policies which vary at the raion (county) level
The unequal scarring effects of a recession on young people's life chances
Large parts of the economy were suspended from late March - June 2020 due to the COVID-19 pandemic. The UK economy shrank by 20% in April 2020 as a result (ONS, 2020a). Given a 2% decline in GDP in the first three months of 2020, a severe recession is inevitable. NIESR's main-case scenario is a 7% economic contraction across 2020 (Lenoel & Young, 2020). The UK Government has sought to buffer the economic effects of this crisis through support such as the Coronavirus Job Retention Scheme (CJRS), allowing employers to place employees on "furlough". However, such schemes are designed to support those already in work, plus likely effects of the increase in employer contributions in August, suggests young people face an extremely challenging job market. Job vacancies were estimated to be 637,000 in February-April 2020; this is a fall of 170,000 compared to the previous 3-month period, which is the largest fall since comparable records began (ONS, 2020b). Henehan (2020) estimates that an additional 640,000 18-24-year-olds could find themselves unemployed this year alone. This note summarises the evidence on the effects of youth unemployment on later outcomes, of father's unemployment on child outcomes, and the unequal effects of recessions on life chances. It then highlights what the literature suggests about how policymakers could buffer some of these negative consequences, and why this may save money in the long run
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