5,249 research outputs found

    Phenotypic Expression in the Paper Wasp \u3ci\u3ePolistes Fuscatus\u3c/i\u3e (Hymenoptera: Vespidae)

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    Quantification of color/color pattern in Polistes fuscatus (Fabricius) revealed that these attributes were the interaction of two antagonistic color sequences; their expression being highly correlated with nest microclimate (relative humidity-temperature). Color/ color pattern expressions were modified under experimental conditions to produce forms having natural counterparts in the field. Principal coordinates analyses and trend surface analyses using specimens collected throughout the United States indicated three color pattern trends, representing three distinct geographic areas, and, when objectively defined, without intergradation between and/or among areas. It was concluded that fuscatus should not be considered a widespread, polytypic species; rather, as three discrete species: an eastern, P. fuscatus (Fabricius); a western, P. aurifer Saussure; and an undescribed yellow form from the southwestern United States

    Trichoptera (Caddisflies) of Watercress Marsh, Columbiana County, Ohio

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    Author Institution: Department of Biological Sciences, Youngstown State University ; Biology Department, Thiel CollegeCaddisfly adults numbering 4,371 were collected by means of light traps at Watercress Marsh, Columbiana Co., Ohio, from June 1976 to October 1981. The marsh occupies a site of the Grand River lobe of the Wisconsin Glacier near its southernmost extent in Columbiana Co. The 69 species in the 10 families collected included 15 species of Limnephilidae and 4 new state records. Seasonal species diversity values were calculated

    The Second International Symposium on Tilapia in Aquaculture

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    Proceedings of the symposium held in 1987 in Bangkok, Thailand, by tilapia scientists to discuss strategies for future research and development in the tilapia industry worldwide. Contains 82 full papers, 17 poster abstracts and author and species indexes. The full papers were presented under 7 sessions: culture systems, management and production; pathology; genetics and reproduction; nutrition, physiology; biology and ecology; and economics and socioeconomics.Tilapia culture, Conferences

    How robust is the evidence of an emerging or increasing female excess in physical morbidity between childhood and adolescence? Results of a systematic literature review and meta-analyses

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    For asthma and psychological morbidity, it is well established that higher prevalence among males in childhood is replaced by higher prevalence among females by adolescence. This review investigates whether there is evidence for a similar emerging female ‘excess’ in relation to a broad range of physical morbidity measures. Establishing whether this pattern is generalised or health outcome-specific will further understandings of the aetiology of gender differences in health. Databases (Medline; Embase; CINAHL; PsycINFO; ERIC) were searched for English language studies (published 1992–2010) presenting physical morbidity prevalence data for males and females, for at least two age-bands within the age-range 4–17 years. A three-stage screening process (initial sifting; detailed inspection; extraction of full papers), was followed by study quality appraisals. Of 11 245 identified studies, 41 met the inclusion criteria. Most (n = 31) presented self-report survey data (five longitudinal, 26 cross-sectional); 10 presented routinely collected data (GP/hospital statistics). Extracted data, supplemented by additional data obtained from authors of the included studies, were used to calculate odds ratios of a female excess, or female:male incident rate ratios as appropriate. To test whether these changed with age, the values were logged and regressed on age in random effects meta-regressions. These showed strongest evidence of an emerging/increasing female excess for self-reported measures of headache, abdominal pain, tiredness, migraine and self-assessed health. Type 1 diabetes and epilepsy, based on routinely collected data, did not show a significant emerging/increasing female excess. For most physical morbidity measures reviewed, the evidence broadly points towards an emerging/increasing female excess during the transition to adolescence, although results varied by morbidity measure and study design, and suggest that this may occur at a younger age than previously thought

    Positive allosteric modulators of the a-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor

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    L-glutamate is the major excitatory neurotransmitter in the mammalian central nervous system (CNS) and plays a fundamental role in the control of motor function, cognition and mood. The physiological effects of glutamate are mediated through two functionally distinct receptor families. While activation of metabotropic (G-protein coupled) glutamate receptors results in modulation of neuronal excitability and transmission, the ionotropic glutamate receptors (ligand-gated ion channels) are responsible for mediating the fast synaptic response to extracellular glutamate

    Faith in the Republic: A Frances Lewis Law Center Conversation

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    Stochastic bacterial population dynamics restrict the establishment of antibiotic resistance from single cells

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    A better understanding of how antibiotic exposure impacts the evolution of resistance in bacterial populations is crucial for designing more sustainable treatment strategies. The conventional approach to this question is to measure the range of concentrations over which resistant strain(s) are selectively favored over a sensitive strain. Here, we instead investigate how antibiotic concentration impacts the initial establishment of resistance from single cells, mimicking the clonal expansion of a resistant lineage following mutation or horizontal gene transfer. Using two Pseudomonas aeruginosa strains carrying resistance plasmids, we show that single resistant cells have <5% probability of detectable outgrowth at antibiotic concentrations as low as one-eighth of the resistant strain’s minimum inhibitory concentration (MIC). This low probability of establishment is due to detrimental effects of antibiotics on resistant cells, coupled with the inherently stochastic nature of cell division and death on the single-cell level, which leads to loss of many nascent resistant lineages. Our findings suggest that moderate doses of antibiotics, well below the MIC of resistant strains, may effectively restrict de novo emergence of resistance even though they cannot clear already-large resistant populations
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