10 research outputs found
Comparison of weakness progression in inclusion body myositis during treatment with methotrexate or placebo
No full textAssociations with autoimmune disorders and HLA class I and II antigens in inclusion body myositis.
No full textWhether autoimmune mechanisms play a role in the pathogenesis of inclusion body myositis (IBM) is unknown. Human leukocyte antigen (HLA) analysis in 52 patients, including 17 with autoimmune disorders (AIDs), showed that patients were more likely to have antigens from the autoimmune-prone HLA-B8-DR3 ancestral haplotype than healthy control subjects, irrespective of the presence of AIDs. Patients lacked the apparently protective HLA-DR53 antigen. The results provide further support for an autoimmune basis in IBM
Associations with autoimmune disorders and HLA class I and II antigens in inclusion body myositis.
No full textHereditary Cerebral Hemorrhage with Amyloidosis-Dutch Type (HCHWA-D): I - A Review of Clinical, Radiologic and Genetic Aspects
No full textA lysosomal marker for activated nicroglial cells involved in Alzheimer classic senile plaques
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