514 research outputs found

    Investigation of microgravity effects on solidification phenomena of selected materials

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    A Get Away Special (GAS) experiment payload to investigate microgravity effects on solidification phenomena of selected experimental samples has been designed for flight. It is intended that the first flight of the assembly will (1) study the p-n junction characteristics for advancing semiconductor device applications, (2) study the effects of gravity-driven convection on the growth of HgCd crystals, (3) compare the textures of the sample which crystallizes in microgravity with those found in chondrite meteorites, and (4) modify glass optical characteristics through divalent oxygen exchange. The space flight experiment consists of many small furnaces. While the experiment payload is in the low gravity environment of orbital flight, the payload controller will sequentially activate the furnaces to heat samples to their melt state and then allow cooling to resolidification in a controlled fashion. The materials processed in the microgravity environment of space will be compared to the same materials processed on earth in a one-gravity environment. This paper discusses the design of all subassemblies (furnance, electronics, and power systems) in the experiment. A complete description of the experimental materials is also presented

    TIX-5:Novel insights into the physiology of the FXa-mediated activation of FV with the aid of a tick protein

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    Within the coagulation system, coagulation factor V (FV) plays a central role with its procoagulant and anticoagulant functions. Our group showed recently that, while FV can become activated by thrombin, activation by factor Xa (FXa) plays a bigger role than originally thought. This was investigated with the aid of the tick salivary protein TIX-5, which functions as an anticoagulant by specifically inhibiting the FXa-mediated activation of FV. This thesis focuses on the development and characterization of a thrombin generation test in plasma that determines the contribution of the FV activation by FXa to thrombin generation using TIX-5. This to gain insight in the inter-individual differences of this pathway in healthy individuals and with the aim to determine whether FXa-mediated activation of FV is involved in patients that suffered from major bleeding or thrombotic events. We show the importance of the activation of FV activation by FXa in healthy person and in patients on anticoagulant treatment. Additionally, we found that the dependence on activation of FV by FXa is also increased during acute thrombosis. Since we discovered the importance of FXa-mediated FV activation for thrombin generation only a few years ago, we now show by employing TIX-5 sensitivity of thrombin generation that this pathway correlates with major cardiovascular complications

    Mortality in organic free-range chickens and molecular characterization of the involved pathogens

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    Longitudinal investigations on causes of mortality were carried out at one organic layer farm with four flocks of Lohman Brown and Lohman White chickens producing table eggs. All flocks were housed separately. One flock of each breed were followed from September 2001 to August 2002. Post mortem examinations were performed on a total of 16% of the dead chickens over the entire period. Of these 346 (96%) of the Lohmann Brown and 315 (91%) of the Lohmann White chickens were subjected for bacteriology. High mortality rates, 91% and 63% were observed in Lohman Brown and Lohman White chickens, respectively and were found to be due to infections with mainly Pasteurella multocida, Erysipelothix rhusiopathia and Escherichia coli. E. rhusiopathia, P. multocida and E. coli were isolated from 46%, 19% and 17%, respectively of the Lohmann Brown chickens. In the flock of Lohmann White chickens P. multocida and E. coli were isolated from 46% and 15%, respectively while E. rhusiopathia was not recorded. P. multocida and E. rhusiopathia isolates were characterized by Restriction Endonuclease Analysis (REA), Restriction Fragment Length Polymorphism (RFLP) and Pulse Field Gel Electrophoresis (PFGE). It was demonstrated that all the P. multocida isolates were genotypic identical over time. The E. rhusiopathia isolates obtained were also identical. It was concluded that the outbreaks caused by P. multocida and E. rhusiopathia were clonal and these two pathogens may cause severe losses in free-range chickens

    Alternative Options to Diesel Fuel in Construction Equipment

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    The construction industry is a major contributor to the environmental emissions due to the extensive use of construction equipment, which is responsible for greenhouse gas emissions and harmful substances such as carbon monoxide, nitrogen oxide and particulate matter emissions. The goal of this paper is to analyze the current equipment and fuel used and to compare to the new fuels that are said to be better for the environment. There have been studies in which companies have employed a portable emission measurement system (PEMS) for real time measurement of emissions from construction equipment including carbon dioxide (CO2), carbon monoxide (CO), as well as nitrous oxide (NO). The alternative fuel options were analyzed based on differences in costs and emissions while also examining the costs and benefits of Tier 4 engines. An interview with a construction professional lead to more insight on Tier 4 engines and their use in the industry. Biofuel is indeed better in terms of cost and emissions when compared to standard diesel. Tier 4 is an option that can greatly reduce emissions by 95 percent. The reduction of these emissions and pollutants is necessary to reduce the impact of the construction industry on our precious planet

    Space station thermal control surfaces

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    Mission planning documents were used to analyze the radiator design and thermal control surface requirements for both space station and 25-kW power module, to analyze the missions, and to determine the thermal control technology needed to satisfy both sets of requirements. Parameters such as thermal control coating degradation, vehicle attitude, self eclipsing, variation in solar constant, albedo, and Earth emission are considered. Four computer programs were developed which provide a preliminary design and evaluation tool for active radiator systems in LEO and GEO. Two programs were developed as general programs for space station analysis. Both types of programs find the radiator-flow solution and evaluate external heat loads in the same way. Fortran listings are included

    Factors influencing reductions in smoking among Australian adolescents

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    © 2016 Harris. A continued increase in the proportion of adolescents who never smoke, as well as an understanding of factors that influence reductions in smoking among this susceptible population, is crucial. The World Health Organization Framework Convention on Tobacco Control provides an appropriate structure to briefly examine Australian and New South Wales policies and programs that are influencing reductions in smoking among adolescents in Australia. This paper provides an overview of price and recent tax measures to reduce the demand for tobacco, the evolution of smoke-free environment policies, changes to tobacco labelling and packaging, public education campaigns, and restrictions to curb tobacco advertising. It also discusses supplyreduction measures that limit adolescents' access to tobacco products. Consideration is given to emerging priorities to achieve continued declines in smoking by Australian adolescents

    Photovoltaic module soiling studies, May 1978 - October 1980

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    Comparative electrical and optical performance data from photovoltaic modules and materials subjected to outdoor exposure at field test sites throughout the United States were collected and examined. The results show significant time and site dependence. During periods when natural removal processes do not dominate, the rate of particulate contamination accumulation appears to be largely material-independent. The effectiveness of natural removal processes, especially rain, is strongly material-dependent. Glass and acrylic top cover materials retain fewer particles than silicone rubber does. Side by side outdoor exposure testing for long duration is presently the most effective means of evaluating soiling differences between materials. Changes in spectral transmission as a function of time and location and limited scattering data are presented
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