993 research outputs found

    Modified Paschos-Wolfenstein relation and extraction of weak mixing angle sin^2 theta_W

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    The NuTeV collaboration reported anomalously large weak mixing angle sin^2 theta_W in comparison with the standard model prediction. Neutrino and antineutrino charged- and neutral-current events are analyzed for extracting sin^2 theta_W. Although the Paschos-Wolfenstein relation is not directly used in the analysis, it plays an important role in the determination. Noting that the target nucleus, iron, is not an isoscalar nucleus, we derive a leading-order expression for a modified Paschos-Wolfenstein relation for nuclei, which may have neutron excess. Then, using charge and baryon-number conservations for nuclei, we discuss a nuclear correction in the sin^2 theta_W determination. It is noteworthy that nuclear modifications are different between valence up- and down-quark distributions. We show this difference effect on the NuTeV sin^2 theta_W deviation.Comment: 5 pages, REVTeX4.0, revtex4.cls, url.sty, natbib.sty, revsymb.sty, 10pt.rtx, aps.rtx, amssymb.sty, amsfonts.sty, 3 eps figures. Phys. Rev. D in press. Email: [email protected] See also http://hs.phys.saga-u.ac.j

    Visualizing cellular heterogeneity by quantifying the dynamics of MAPK activity in live mammalian cells with synthetic fluorescent biosensors.

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    Mitogen-Activated Protein Kinases (MAPKs) control a wide array of cellular functions by transducing extracellular information into defined biological responses. In order to understand how these pathways are regulated, dynamic single cell measurements are highly needed. Fluorescence microscopy is well suited to perform these measurements. However, more dynamic and sensitive biosensors that allow the quantification of signaling activity in living mammalian cells are required. We have engineered a synthetic fluorescent substrate for human MAPKs (ERK, JNK and p38) that relocates from the nucleus to the cytoplasm when phosphorylated by the kinases. We demonstrate that this reporter displays an improved response compared to other relocation biosensors. This assay allows to monitor the heterogeneity in the MAPK response in a population of isogenic cells, revealing pulses of ERK activity upon a physiological EGFR stimulation. We show applicability of this approach to the analysis of multiple cancer cell lines and primary cells as well as its application in vivo to developing tumors. Using this ERK biosensor, dynamic single cell measurements with high temporal resolution can be obtained. These MAPK reporters can be widely applied to the analysis of molecular mechanisms of MAPK signaling in healthy and diseased state, in cell culture assays or in vivo

    The CDF dijet excess from intrinsic quarks

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    The CDF collaboration reported an excess in the production of two jets in association with a WW. We discuss constraints on possible new particle state interpretations of this excess. The fact of no statistically significant deviation from the SM expectation for {ZZ+dijet} events in CDF data disfavors the new particle explanation. We show that the nucleon intrinsic strange quarks provide an important contribution to the WW boson production in association with a single top quark production. Such {WW+t} single top quark production can contribute to the CDF {WW+dijet} excess, thus the nucleon intrinsic quarks can provide a possible explanation to the CDF excess in {WW+dijet} but not in {ZZ+dijet} events.Comment: 4 latex pages, 1 figure. Version for journal publicatio

    Pion-photon and photon-pion transition form factors in light-cone formalism

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    We derive the minimal Fock-state expansions of the pion and the photon wave functions in light-cone formalism, then we calculate the pion-photon and the photon-pion transition form factors of γπ0γ\gamma ^{\ast}\pi ^{0}\to \gamma and γγπ0\gamma ^{\ast}\gamma \to \pi ^{0} processes by employing these quark-antiquark wave functions of the pion and the photon. We find that our calculation for the γγπ0\gamma ^{\ast}\gamma \to \pi ^{0} transition form factor agrees with the experimental data at low and moderately high energy scale. Moreover, the physical differences and inherent connections between the transition form factors of γπ0γ\gamma ^{\ast}\pi ^{0}\to \gamma and γγπ0 \gamma ^{\ast}\gamma \to \pi ^{0} have been illustrated, which indicate that these two physical processes are intrinsically related. In addition, we also discuss the π0γγ\pi ^{0}\to \gamma \gamma form factor and the decay width Γ(πγγ) \mathit{\Gamma}(\pi \to \gamma \gamma) at Q2=0Q^{2}=0.Comment: 20 pages, 2 figure

    The Proton Spin and the Wigner Rotation

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    It is shown that in both the gluonic and strange sea explanations of the Ellis-Jaffe sum rule violation discovered by the European Muon Collaboration (EMC), the spin of the proton, when viewed in in its rest reference frame, could by fully provided by quarks and antiquarks within a simple quark model picture, taken into account the relativistic effect from the Wigner rotation.Comment: 13 latex page

    Anomalous Neutrino Interaction, Muon g-2, and Atomic Parity Nonconservation

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    We propose a simple unified description of two recent precision measurements which suggest new physics beyond the Standard Model of particle interactions, i.e. the deviation of sin2θW\sin^2 \theta_W in deep inelastic neutrino-nucleon scattering and that of the anomalous magnetic moment of the muon. Our proposal is also consistent with a third precision measurement, i.e. that of parity nonconservation in atomic Cesium, which agrees with the Standard Model.Comment: 9 pages, including 1 figure, latest muon g-2 information adde

    Resonant inelastic x-ray scattering (RIXS) spectra of magnesium diboride

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    Using the tight-binding linear muffin-tin orbitals method, the soft x-ray fluorescence K-emission spectra of boron in MgB_2, excited close to the absorption edge, are estimated. In the calculations the angle of incidence between the direction of the incoming photon and the hexagonal axis of the specimen is 60 degrees and 75 degrees. Comparison with experiment is possible in the former case where good agreement is found. Furthermore, another resonant feature below the Fermi energy is predicted for the larger angle. This feature can be related to the excitations to the antibonding B pi-band in the neighbourhood of the L-H line in the Brillouin zone.Comment: 4 pages with 4 figure

    New insights into the role of DNA synthesis in meiotic recombination

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    Meiosis comprises two rounds of nuclear division following a single phase of DNA replication, leading to the production of haploid gametes and is essential for sexual reproduction in eukaryotes. Unlike mitosis, meiosis involves homologous chromosome pairing, synapsis, and recombination during prophase I. Meiotic recombination not only ensures the accurate segregation of homologs, but also redistributes alleles among offspring. DNA synthesis is a critical process during meiotic recombination, but our understanding of the proteins that execute and regulate it is limited. This review summarizes the recent advances in defining the role of DNA synthesis in meiotic recombination through analyses of DNA synthesis genes, with specific emphasis on DNA polymerases (e.g., Polε and Polδ), replication processivity factor RFC1 and translesion polymerases (e.g., Polζ). We also present a new double strand break repair model for meiotic recombination, which includes lagging strand DNA synthesis and leading strand elongation. Finally, we propose that DNA synthesis is one of critical factors for discriminating meiotic recombination pathways and that this differentiation may be conserved among eukaryotes

    The influence of direct DD-meson production to the determination on the nucleon strangeness asymmetry via dimuon events in neutrino experiments

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    Experimentally, the production of oppositely charged dimuon events by neutrino and anti-neutrino deep inelastic scattering (DIS) is used to determine the strangeness asymmetry inside a nucleon. Here we point out that the direct production of DD-meson in DIS may make substantial influence to the measurement of nucleon strange distributions. The direct DD-meson production is via the heavy quark recombination (HQR) and via the light quark fragmentation from perturbative QCD (LQF-P). To see the influence precisely, we compute the direct DD-meson productions via HQR and LQF-P quantitatively and estimate their corrections to the analysis of the strangeness asymmetry. The results show that HQR has stronger effect than LQF-P does, and the former may influence the experimental determination of the nucleon strangeness asymmetry.Comment: 9 latex pages, 7 figure

    The NuTeV Anomaly, Neutrino Mixing, and a Heavy Higgs Boson

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    Recent results from the NuTeV experiment at Fermilab and the deviation of the Z invisible width, measured at LEP/SLC, from its Standard Model (SM) prediction suggest the suppression of neutrino-Z couplings. Such suppressions occur naturally in models which mix the neutrinos with heavy gauge singlet states. We postulate a universal suppression of the Z-nu-nu couplings by a factor of (1-epsilon) and perform a fit to the Z-pole and NuTeV observables with epsilon and the oblique correction parameters S and T. Compared to a fit with S and T only, inclusion of epsilon leads to a dramatic improvement in the quality of the fit. The values of S and T preferred by the fit can be obtained within the SM by a simple increase in the Higgs boson mass. However, if the W mass is also included in the fit, a non-zero U parameter becomes necessary which cannot be supplied within the SM. The preferred value of epsilon suggests that the seesaw mechanism may not be the reason why neutrinos are so light.Comment: 19 pages, REVTeX4, 8 postscript figures. Updated references. Typos correcte
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