14 research outputs found
A hunter-gatherer-farmer population model: Lie symmetries, exact solutions and their interpretation
The Lie symmetry classification of the known three-component
reaction-diffusion system modelling the spread of an initially localized
population of farmers into a region occupied by hunter-gatherers is derived.
The Lie symmetries obtained for reducing the system in question to systems of
ODEs and constructing exact solutions are applied. Several exact solutions of
traveling front type are found, their properties are identified and biological
interpretation is discussed
Baseline characteristics of the study group based on rs4977574 genotype (risk allele- G).
<p>eGFR- estimated GFR, mean values with standard deviations are given, unless otherwise specified.</p
The rs4977574 polymorphism and 5-year survival.
<p>No significant differences were observed between the genotypes.</p
The rs4977574 polymorphism and 5-year survival – medium and low-risk patients (Grace risk score <155).
<p>No significant differences were observed between the genotypes.</p
Univariate and multivariate analysis for 5-year mortality in a subgroup of high-risk patients (Grace risk score ≥155).
<p>In the brackets values adjusted for severity of coronary artery disease (number of vessels with significant stenosis) are given.</p
The rs4977574 polymorphism and 5-year survival - subgroup of high-risk patients (Grace risk score ≥155).
<p>AA low-risk homozygotes had significantly higher probability of survival compared to other genotypes (p = 0.008 after adjustment for Bonferroni correction, log-rank test).</p
Baseline characteristics of the study group based on rs10757278 genotype (risk allele for MI- G).
<p>eGFR- estimated GFR, mean values with standard deviations are given, unless otherwise specified.</p
The rs10757278 polymorphism and long-term survival in the derivation group.
<p>No significant differences were observed between the genotypes.</p
Linkage disequilibrium of investigated SNPs.
<p>Linkage disequilibrium of investigated SNPs.</p
Percentages of specific genotypes and associated mortality rates.
1<p>p = 0.007; <sup>2</sup>p = 0.019; <sup>3</sup>p = 0.011; chi-2 tests for 3 genotypes; all p values adjusted for Bonferroni correction.</p