Chemical composition and antioxidant, antibacterial activity of <i>Cirsium rivulare</i> (Jacq) All. roots

<p>The mixture of three phytosterols (campesterol, stigmasterol and <i>β</i>-sitosterol), <i>β</i>-sitosterol 3-<i>O</i>-glucoside and syringin were isolated from hexane and methanol extract of <i>Cirsium rivulare</i> roots after chromatographic separation. The main component of the source was syringin which was obtained with the yield 0.08% of the dry source. In hexane extract, the qualitative and quantitative composition of fatty acids was determined. The predominant component was linoleic acid (23.31 mg/g of extract). The extracts showed antioxidant activity. The ability to scavenge DPPH• free radical was in correlation with appointed total phenol content. The not-defatted methanolic extract was the most active. Hexane and defatted methanol extracts showed moderate antibacterial activity against G(+) and G(−) strains with MIC and MBC ranged from 25 to 200 μg/mL.</p