478 research outputs found
Dielectric (p,q) Strings in a Throat
We calculate the (p,q) string spectrum in a warped deformed conifold using
the dielectric brane method. The spectrum is shown to have the same functional
form as in the dual picture of a wrapped D3-brane with electric and magnetic
fluxes on its world volume. The agreement is exact in the limit where q is
large. We also calculate the dielectric spectrum in the S-dual picture. The
spectrum in the S-dual picture has the same form as in the original picture but
it is not exactly S-dual invariant due to an interchange of Casimirs of the
non-Abelian gauge symmetries. We argue that in order to restore S-duality
invariance the non-Abelian brane action should be refined, probably by a better
prescription for the non-Abelian trace operation
The (p,q) String Tension in a Warped Deformed Conifold
We find the tension spectrum of the bound states of p fundamental strings and
q D-strings at the bottom of a warped deformed conifold. We show that it can be
obtained from a D3-brane wrapping a 2-cycle that is stabilized by both electric
and magnetic fluxes. Because the F-strings are Z_M-charged with non-zero
binding energy, binding can take place even if (p,q) are not coprime.
Implications for cosmic strings are briefly discussed.Comment: 17 pages, 1 figur
Students with global experiences during medical school are more likely to work in settings that focus on the underserved: an observational study from a public U.S. institution
Background: Global health interest has grown among medical students over the past 20 years, and most medical schools offer global health opportunities. Studies suggest that completing global health electives during medical school may increase the likelihood of working with underserved populations in a clinical or research capacity. This study aimed to assess the association of global electives in medical school on subsequently working in global health and with underserved populations in the United States (U.S.), additionally considering students’ interests and experiences prior to medical school. We also examined whether respondents perceived benefits gained from global electives. Methods: We surveyed medical school graduates (classes of 2011-2015) from a large public medical school in the U.S. to describe current practice settings and previous global health experience. We evaluated work, volunteer, and educational experiences preceding medical school, socioeconomic status, race and ethnicity using American Medical College Application Service (AMCAS) data. We assessed the association between students’ backgrounds, completing global health electives in medical school and current work in global health or with underserved populations in the U.S. Results: In the 5 to 8 years post-graduation, 78% of 161 respondents reported work, research, or teaching with a focus on global or underserved U.S. populations. Completing a global health elective during medical school (p = 0.0002) or during residency (p = 0.06) were positively associated with currently working with underserved populations in the U.S. and pre-medical school experiences were marginally associated (p = 0.1). Adjusting for pre-medical school experiences, completing a global health elective during medical school was associated with a 22% greater prevalence of working with an underserved population. Perceived benefits from global electives included improved cultural awareness, language skills, public health and research skills, and ability to practice in technology-limited settings. Conclusion: Medical school graduates who participated in global electives as students were more likely than their peers to pursue careers with underserved populations, independent of experiences prior to medical school. We hypothesize that by offering global health experiences, medical schools can enhance the interests and skills of graduates that will make them more likely and better prepared to work with underserved populations in the U.S. and abroad
Non-Abelian (p,q) Strings in the Warped Deformed Conifold
We calculate the tension of -strings in the warped deformed conifold
using the non-Abelian DBI action. In the large flux limit, we find exact
agreement with the recent expression obtained by Firouzjahi, Leblond and
Henry-Tye up to and including order terms if is also taken to be
large. Furthermore using the finite prescription for the symmetrised trace
operation we anticipate the most general expression for the tension valid for
any . We find that even in this instance, corrections to the tension
scale as which is not consistent with simple Casimir scaling.Comment: 18 pages, Latex, 1 figure; Added a discussion of the case when the
warp factor parameter and typos correcte
Prevalence of hypertension and its associated risk factors in a rural black population of Mthatha town,South Africa
The occurrence of hypertension has been increasing alarmingly in both low and middle-income countries. Despite acknowledging hypertension as the most common life-threatening risk factor for cardiovascular disease (CVD), a dearth of data is available on the prevalence, awareness, and determinants of hypertension in rural parts of South Africa. The principal aim of the current study is to determine the prevalence and associated risk factors of hypertension among a black rural African population from the Mtatha town of Eastern Cape Province. Methods: This was a cross-sectional study, and individuals over 18 years of age were randomly screened using a World Health Organization stepwise questionnaire. Sociodemographic information, anthropometric measurements, fasting blood glucose levels, and three independent blood pressure (BP) readings were measured. Blood pressure measurements were classified according to the American Heart Association guidelines. Univariate and multivariate analyses were performed to determine the significant predictors of hypertension. Results: Of the total participants (n = 556), 71% of individuals had BP scores in the hypertensive range. In univariate analysis, age, westernized diet, education, income, and diabetic status, as well as overweight/obese status were positively associated with the prevalence of hypertension
Can inflationary models of cosmic perturbations evade the secondary oscillation test?
We consider the consequences of an observed Cosmic Microwave Background (CMB)
temperature anisotropy spectrum containing no secondary oscillations. While
such a spectrum is generally considered to be a robust signature of active
structure formation, we show that such a spectrum {\em can} be produced by
(very unusual) inflationary models or other passive evolution models. However,
we show that for all these passive models the characteristic oscillations would
show up in other observable spectra. Our work shows that when CMB polarization
and matter power spectra are taken into account secondary oscillations are
indeed a signature of even these very exotic passive models. We construct a
measure of the observability of secondary oscillations in a given experiment,
and show that even with foregrounds both the MAP and \pk satellites should be
able to distinguish between models with and without oscillations. Thus we
conclude that inflationary and other passive models can {\em not} evade the
secondary oscillation test.Comment: Final version accepted for publication in PRD. Minor improvements
have been made to the discussion and new data has been included. The
conclusions are unchagne
Modelling and control of a marine current turbine-driven doubly fed induction generator
Machine Learning in Automated Text Categorization
The automated categorization (or classification) of texts into predefined
categories has witnessed a booming interest in the last ten years, due to the
increased availability of documents in digital form and the ensuing need to
organize them. In the research community the dominant approach to this problem
is based on machine learning techniques: a general inductive process
automatically builds a classifier by learning, from a set of preclassified
documents, the characteristics of the categories. The advantages of this
approach over the knowledge engineering approach (consisting in the manual
definition of a classifier by domain experts) are a very good effectiveness,
considerable savings in terms of expert manpower, and straightforward
portability to different domains. This survey discusses the main approaches to
text categorization that fall within the machine learning paradigm. We will
discuss in detail issues pertaining to three different problems, namely
document representation, classifier construction, and classifier evaluation.Comment: Accepted for publication on ACM Computing Survey
Corrections to flat-space particle dynamics arising from space granularity
The construction of effective Hamiltonians describing corrections to flat
space particle dynamics arising from the granularity of space at very short
distances is discussed in the framework of an heuristic approach to the
semiclassical limit of loop quantum gravity. After some general motivation of
the subject, a brief non-specialist introduction to the basic tools employed in
the loop approach is presented. The heuristical semiclassical limit is
subsequently defined and the application to the case of photons and spin 1/2
fermions is described. The resulting modified Maxwell and Dirac Hamiltonians,
leading in particular to Planck scale corrections in the energy-momentum
relations, are presented. Alternative interpretations of the results and their
limitations, together with other approaches are briefly discussed along the
text. Three topics related to the above methods are reviewed: (1) The
determination of bounds to the Lorentz violating parameters in the fermionic
sector, obtained from clock comparison experiments.(2) The calculation of
radiative corrections in preferred frames associated to space granularity in
the framework of a Yukawa model for the interactions and (3) The calculation of
synchrotron radiation in the framework of the Myers-Pospelov effective theories
describing Lorentz invariance violations, as well as a generalized approach to
radiation in Planck scale modified electrodynamics. The above exploratory
results show that quantum gravity phenomenology provides observational guidance
in the construction of quantum gravity theories and opens up the possibility of
probing Planck scale physics.Comment: 49 pages, 6 figures and 4 tables. Extended version of the talk given
at the 339-th WE-Heraeus-Seminar: Special Relativity, will it survive the
next 100 years?, Potsdam, february 200
Circulating syndecan-1 is reduced in pregnancies with poor fetal growth and its secretion regulated by matrix metalloproteinases and the mitochondria
Fetal growth restriction is a leading cause of stillbirth that often remains undetected during pregnancy. Identifying novel biomarkers may improve detection of pregnancies at risk. This study aimed to assess syndecan-1 as a biomarker for small for gestational age (SGA) or fetal growth restricted (FGR) pregnancies and determine its molecular regulation. Circulating maternal syndecan-1 was measured in several cohorts; a large prospective cohort collected around 36 weeks' gestation (n = 1206), a case control study from the Manchester Antenatal Vascular service (285 women sampled at 24-34 weeks' gestation); two prospective cohorts collected on the day of delivery (36 + 3-41 + 3 weeks' gestation, n = 562 and n = 405 respectively) and a cohort who delivered for preterm FGR (< 34 weeks). Circulating syndecan-1 was consistently reduced in women destined to deliver growth restricted infants and those delivering for preterm disease. Syndecan-1 secretion was reduced by hypoxia, and its loss impaired proliferation. Matrix metalloproteinases and mitochondrial electron transport chain inhibitors significantly reduced syndecan-1 secretion, an effect that was rescued by coadministration of succinate, a mitochondrial electron transport chain activator. In conclusion, circulating syndecan-1 is reduced among cases of term and preterm growth restriction and has potential for inclusion in multi-marker algorithms to improve detection of poorly grown fetuses
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