5 research outputs found
A multimodal deep learning framework using local feature representations for face recognition
YesThe most recent face recognition systems are
mainly dependent on feature representations obtained using
either local handcrafted-descriptors, such as local binary patterns
(LBP), or use a deep learning approach, such as deep
belief network (DBN). However, the former usually suffers
from the wide variations in face images, while the latter
usually discards the local facial features, which are proven
to be important for face recognition. In this paper, a novel
framework based on merging the advantages of the local
handcrafted feature descriptors with the DBN is proposed to
address the face recognition problem in unconstrained conditions.
Firstly, a novel multimodal local feature extraction
approach based on merging the advantages of the Curvelet
transform with Fractal dimension is proposed and termed
the Curvelet–Fractal approach. The main motivation of this
approach is that theCurvelet transform, a newanisotropic and
multidirectional transform, can efficiently represent themain
structure of the face (e.g., edges and curves), while the Fractal
dimension is one of the most powerful texture descriptors
for face images. Secondly, a novel framework is proposed,
termed the multimodal deep face recognition (MDFR)framework,
to add feature representations by training aDBNon top
of the local feature representations instead of the pixel intensity
representations. We demonstrate that representations acquired by the proposed MDFR framework are complementary
to those acquired by the Curvelet–Fractal approach.
Finally, the performance of the proposed approaches has
been evaluated by conducting a number of extensive experiments
on four large-scale face datasets: the SDUMLA-HMT,
FERET, CAS-PEAL-R1, and LFW databases. The results
obtained from the proposed approaches outperform other
state-of-the-art of approaches (e.g., LBP, DBN, WPCA) by
achieving new state-of-the-art results on all the employed
datasets
Corneal confocal microscopy detects a reduction in corneal endothelial cells and nerve fibres in patients with acute ischemic stroke
YesEndothelial dysfunction and damage underlie cerebrovascular disease and ischemic stroke. We
undertook corneal confocal microscopy (CCM) to quantify corneal endothelial cell and nerve
morphology in 146 patients with an acute ischemic stroke and 18 age-matched healthy control
participants. Corneal endothelial cell density was lower (P<0.001) and endothelial cell area (P<0.001)
and perimeter (P<0.001) were higher, whilst corneal nerve fbre density (P<0.001), corneal nerve
branch density (P<0.001) and corneal nerve fbre length (P=0.001) were lower in patients with acute
ischemic stroke compared to controls. Corneal endothelial cell density, cell area and cell perimeter
correlated with corneal nerve fber density (P=0.033, P=0.014, P=0.011) and length (P=0.017,
P=0.013, P=0.008), respectively. Multiple linear regression analysis showed a signifcant independent
association between corneal endothelial cell density, area and perimeter with acute ischemic stroke
and triglycerides. CCM is a rapid non-invasive ophthalmic imaging technique, which could be used to
identify patients at risk of acute ischemic stroke.Qatar National Research Fund Grant BMRP2003865
Cytotoxicity and physicochemical characterization of iron–manganese-doped sulfated zirconia nanoparticles
Mohamed Qasim Al-Fahdawi,1 Abdullah Rasedee,1,2 Mothanna Sadiq Al-Qubaisi,1 Fatah H Alhassan,3,4 Rozita Rosli,1 Mohamed Ezzat El Zowalaty,1,5 Seïf-Eddine Naadja,6 Thomas J Webster,7,8 Yun Hin Taufiq-Yap3,41Institute of Bioscience, 2Department of Veterinary Pathology and Microbiology, Faculty of Veterinary Medicine, 3Catalysis Science and Technology Research Centre, Faculty of Science, 4Department of Chemistry, Faculty of Science, 5Biomedical Research Center, Qatar University, Doha, Qatar; 6Department of Cell and Molecular Biology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia (UPM), Serdang, Selangor, Malaysia; 7Department of Chemical Engineering, Northeastern University, Boston, MA, USA; 8Center of Excellence for Advanced Materials Research, King Abdulaziz University, Jeddah, Saudi ArabiaAbstract: Iron–manganese-doped sulfated zirconia nanoparticles with both Lewis and Brønsted acidic sites were prepared by a hydrothermal impregnation method followed by calcination at 650°C for 5 hours, and their cytotoxicity properties against cancer cell lines were determined. The characterization was carried out using X-ray diffraction, thermogravimetric analysis, Fourier transform infrared spectroscopy, Brauner–Emmett–Teller (BET) surface area measurements, X-ray fluorescence, X-ray photoelectron spectroscopy, zeta size potential, and transmission electron microscopy (TEM). The cytotoxicity of iron–manganese-doped sulfated zirconia nanoparticles was determined using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assays against three human cancer cell lines (breast cancer MDA-MB231 cells, colon carcinoma HT29 cells, and hepatocellular carcinoma HepG2 cells) and two normal human cell lines (normal hepatocyte Chang cells and normal human umbilical vein endothelial cells [HUVECs]). The results suggest for the first time that iron–manganese-doped sulfated zirconia nanoparticles are cytotoxic to MDA-MB231 and HepG2 cancer cells but have less toxicity to HT29 and normal cells at concentrations from 7.8 µg/mL to 500 µg/mL. The morphology of the treated cells was also studied, and the results supported those from the cytotoxicity study in that the nanoparticle-treated HepG2 and MDA-MB231 cells had more dramatic changes in cell morphology than the HT29 cells. In this manner, this study provides the first evidence that iron–manganese-doped sulfated zirconia nanoparticles should be further studied for a wide range of cancer applications without detrimental effects on healthy cell functions.Keywords: nanopartices, Lewis and Brønsted acidic sites, anticancer applications, HT29 cells, transition metal oxid
Cytotoxicity and physicochemical characterization of iron–manganese-doped sulfated zirconia nanoparticles [Corrigendum]
Al-Fahdawi MQ, Rasedee A, Al-Qubaisi MS, et al. Int J Nanomedicine. 2015;10:5739–5750.On page 5739, Affiliation section, the affiliations "1Institute of Bioscience, 2Department of Veterinary Pathology and Microbiology, Faculty of Veterinary Medicine, 3Catalysis Science and Technology Research Centre, Faculty of Science, 4Department of Chemistry, Faculty of Science, 5Biomedical Research Center, Qatar University, Doha, Qatar; 6Department of Cell and Molecular Biology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia (UPM), Serdang, Selangor, Malaysia; 7Department of Chemical Engineering, Northeastern University, Boston, MA, USA; 8Center of Excellence for Advanced Materials King Abdulaziz University, Jeddah, Saudi Arabia" should have read "1Institute of Bioscience, 2Department of Veterinary Pathology and Microbiology, Faculty of Veterinary Medicine, 3Catalysis Science and Technology Research Centre, Faculty of Science, 4Department of Chemistry, Faculty of Science, Universiti Putra Malaysia (UPM), Serdang, Selangor, Malaysia; 5Biomedical Research Center, Qatar University, Doha, Qatar; 6Department of Cell and Molecular Biology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia (UPM), Serdang, Selangor, Malaysia; 7Department of Chemical Engineering, Northeastern University, Boston, MA, USA; 8Center of Excellence for Advanced Materials Research, King Abdulaziz University, Jeddah, Saudi ArabiaRead the original articl