6,990 research outputs found
The scenario of two-dimensional instabilities of the cylinder wake under EHD forcing: A linear stability analysis
We propose to study the stability properties of an air flow wake forced by a dielectric barrier discharge (DBD) actuator, which is a type of electrohydrodynamic (EHD) actuator. These actuators add momentum to the flow around a cylinder in regions close to the wall and, in our case, are symmetrically disposed near the boundary layer separation point.
Since the forcing frequencies, typical of DBD, are much higher than the natural shedding frequency of the flow, we will be considering the forcing actuation as stationary.
In the first part, the flow around a circular cylinder modified by EHD actuators will be experimentally studied by means of particle image velocimetry (PIV). In the second part, the EHD actuators have been numerically implemented as a boundary condition on the cylinder surface. Using this boundary condition, the computationally obtained base flow is then compared with the experimental one in order to relate the control parameters from both methodologies.
After validating the obtained agreement, we study the Hopf bifurcation that appears once the flow starts the vortex shedding through experimental and computational approaches. For the base flow derived from experimentally obtained snapshots, we monitor the evolution of the velocity amplitude oscillations. As to the computationally obtained base flow, its stability is analyzed by solving a global eigenvalue problem obtained from the linearized Navier–Stokes equations. Finally, the critical parameters obtained from both approaches are compared
Acute-on-chronic liver failure: Definitions, pathophysiology and principles of treatment
The term acute-on-chronic liver failure (ACLF) defines an abrupt and life-threatening worsening of clinical conditions in patients with cirrhosis or chronic liver disease. In recent years, different definitions and diagnostic criteria for the syndrome have been proposed by the major international scientific societies. The main controversies relate to the type of acute insult (specifically hepatic or also extrahepatic), the stage of underlying liver disease (cirrhosis or chronic hepatitis) and the concomitant extrahepatic organ failure(s) that should be considered in the definition of ACLF. Therefore, different severity criteria and prognostic scores have been proposed and validated. Current evidence shows that the pathophysiology of ACLF is closely associated with an intense systemic inflammation sustained by circulating pathogen-associated molecular patterns and damage-associated molecular patterns. The development of organ failures may be a result of a combination of tissue hypoperfusion, direct immune-mediated damage and mitochondrial dysfunction. Management of ACLF is currently based on the supportive treatment of organ failures, mainly in an intensive care setting. For selected patients, liver transplantation is an effective treatment that offers a good long-term prognosis. Future studies on potential mechanistic treatments that improve patient survival are eagerly awaited
Magnetic hydrodynamics with asymmetric stress tensor
In this paper we study equations of magnetic hydrodynamics with a stress
tensor. We interpret this system as the generalized Euler equation associated
with an abelian extension of the Lie algebra of vector fields with a
non-trivial 2-cocycle. We use the Lie algebra approach to prove the energy
conservation law and the conservation of cross-helicity
Developement of real time diagnostics and feedback algorithms for JET in view of the next step
Real time control of many plasma parameters will be an essential aspect in
the development of reliable high performance operation of Next Step Tokamaks.
The main prerequisites for any feedback scheme are the precise real-time
determination of the quantities to be controlled, requiring top quality and
highly reliable diagnostics, and the availability of robust control algorithms.
A new set of real time diagnostics was recently implemented on JET to prove the
feasibility of determining, with high accuracy and time resolution, the most
important plasma quantities. With regard to feedback algorithms, new
model–based controllers were developed to allow a more robust control of
several plasma parameters. Both diagnostics and algorithms were successfully
used in several experiments, ranging from H-mode plasmas to configuration with
ITBs. Since elaboration of computationally heavy measurements is often
required, significant attention was devoted to non-algorithmic methods like
Digital or Cellular Neural/Nonlinear Networks. The real time hardware and
software adopted architectures are also described with particular attention to
their relevance to ITER.Comment: 12th International Congress on Plasma Physics, 25-29 October 2004,
Nice (France
Structure of the Wake of a Magnetic Obstacle
We use a combination of numerical simulations and experiments to elucidate
the structure of the flow of an electrically conducting fluid past a localized
magnetic field, called magnetic obstacle. We demonstrate that the stationary
flow pattern is considerably more complex than in the wake behind an ordinary
body. The steady flow is shown to undergo two bifurcations (rather than one)
and to involve up to six (rather than just two) vortices. We find that the
first bifurcation leads to the formation of a pair of vortices within the
region of magnetic field that we call inner magnetic vortices, whereas a second
bifurcation gives rise to a pair of attached vortices that are linked to the
inner vortices by connecting vortices.Comment: 4 pages, 5 figures, corrected two typos, accepted for PR
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Inferring Phylogenies from RAD Sequence Data
Reduced-representation genome sequencing represents a new source of data for systematics, and its potential utility in interspecific phylogeny reconstruction has not yet been explored. One approach that seems especially promising is the use of inexpensive short-read technologies (e.g., Illumina, SOLiD) to sequence restriction-site associated DNA (RAD) – the regions of the genome that flank the recognition sites of restriction enzymes. In this study, we simulated the collection of RAD sequences from sequenced genomes of different taxa (Drosophila, mammals, and yeasts) and developed a proof-of-concept workflow to test whether informative data could be extracted and used to accurately reconstruct “known” phylogenies of species within each group. The workflow consists of three basic steps: first, sequences are clustered by similarity to estimate orthology; second, clusters are filtered by taxonomic coverage; and third, they are aligned and concatenated for “total evidence” phylogenetic analysis. We evaluated the performance of clustering and filtering parameters by comparing the resulting topologies with well-supported reference trees and we were able to identify conditions under which the reference tree was inferred with high support. For Drosophila, whole genome alignments allowed us to directly evaluate which parameters most consistently recovered orthologous sequences. For the parameter ranges explored, we recovered the best results at the low ends of sequence similarity and taxonomic representation of loci; these generated the largest supermatrices with the highest proportion of missing data. Applications of the method to mammals and yeasts were less successful, which we suggest may be due partly to their much deeper evolutionary divergence times compared to Drosophila (crown ages of approximately 100 and 300 versus 60 Mya, respectively). RAD sequences thus appear to hold promise for reconstructing phylogenetic relationships in younger clades in which sufficient numbers of orthologous restriction sites are retained across species.</p
Force transmission in a packing of pentagonal particles
We perform a detailed analysis of the contact force network in a dense
confined packing of pentagonal particles simulated by means of the contact
dynamics method. The effect of particle shape is evidenced by comparing the
data from pentagon packing and from a packing with identical characteristics
except for the circular shape of the particles. A counterintuitive finding of
this work is that, under steady shearing, the pentagon packing develops a lower
structural anisotropy than the disk packing. We show that this weakness is
compensated by a higher force anisotropy, leading to enhanced shear strength of
the pentagon packing. We revisit "strong" and "weak" force networks in the
pentagon packing, but our simulation data provide also evidence for a large
class of "very weak" forces carried mainly by vertex-to-edge contacts. The
strong force chains are mostly composed of edge-to-edge contacts with a marked
zig-zag aspect and a decreasing exponential probability distribution as in a
disk packing
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