Correction: Increasing ion yield circular dichroism in femtosecond photoionisation using optimal control theory

Correction for ‘Increasing ion yield circular dichroism in femtosecond photoionisation using optimal control theory’ by Manel Mondelo-Martell et al., Phys. Chem. Chem. Phys., 2022, 24, 9286–9297, https://doi.org/10.1039/D1CP05239J. The authors have detected two issues in the numerical simulations reported in the originally published version of the article. First, the values of the electric and magnetic transition moments, obtained from quantum chemistry calculations were not sufficiently converged. Second, there was a mistake in the implementation of the rotational averaging in the model. After fixing these errors and choosing an improved optimisation functional, new simulations yield quantitatively different results. However, the physical mechanisms of the optimised pulses identified in the original paper remain valid. Here, the authors summarise the origin of the errors in the original publication and present newly converged energies, permanent and transition moments, as well as corrected figures and conclusions. Specifically, Tables 1 and 2 in the original article have been replaced with the corresponding tables in this correction, and Fig. 2–5 in the original article by Fig. 1–4 in this correction respectively. The authors also introduce and explain the new functional that has been used to optimise the pulse

Development of local strontium ranelate delivery systems and long term in vitro drug release studies in osteogenic medium

Funding Information: The authors acknowledge financial support from the Latvian Academy of Sciences though the ERANet under the frame of EuroNanoMed-II (Nanoforosteo, Project number: Z/14/1187) and the Riga Technical University and Riga Stardiņš University Cooperation Research Project No. RTU/RSU-18. Publisher Copyright: © 2018, The Author(s).It has been recognized that the operative stabilization of osteoporotic fractures should be followed up with an appropriate osteoporosis treatment in order to decrease the risk of repeated fractures. Despite the good clinical results of strontium ranelate (SrRan) towards the osteoporosis treatment, high drug doses and long treatment period cause an increased risk of serious side effects. Novel local SrRan/poly(lactic acid) (SrRan/PLA) delivery systems containing from 3.57 ± 0.28 wt% to 24.39 ± 0.91 wt% of active substance were developed. In order to resemble the naturally occurring processes, osteogenic media (OM) was used as a release medium for long term (121 days) in vitro drug release studies and UV/VIS method for the determination of SrRan content in OM was developed and validated. Biomimetic calcium phosphate precipitates were found on the surface and in the pores of prepared delivery system after microcapsule exposure to OM for 121 days as well as SrRan particles, indicating that the release of the drug have not been completed within 121 days. In vitro cell viability evaluation approved no cytotoxic effects of microcapsule suspensions and extracts.publishersversionPeer reviewe

Increasing ion yield circular dichroism in femtosecond photoionisation using optimal control theory

We investigate how optimal control theory can be used to improve Circular Dichroism (CD) signals for the A-band of fenchone measured via the photoionization yield upon further excitation. These transitions are electric dipole forbidden to first order, which translates into low population transfer to the excited state but allows for a clearer interplay between electric and magnetic transition dipole moments, which are of the same order of magnitude. Using a model including the electronic ground and excited A state as well as all permanent and transition multipole moments up to the electric quadrupole, we find that the absolute CD signal of randomly oriented molecules can be increased by a factor of 2.5 when using shaped laser pulses, with the anisotropy parameter g increasing from 0.06 to 1. We find that this effect is caused by the interference between the excitation pathways prompted by the different multipole moments of the molecule

Towards an International Standard on Occupational Health and Safety Management

As a result of the need for companies to manage occupational health and safety, as well as the absence of a globally accepted international standard, numerous organisations have developed their own models in the shape of guides, standards, or guidelines. However, the resultant dispersion is creating confusion among companies, rather than making life easier for them. In this article, we look at the current situation as far as available European management systems are concerned, and the emergent trends in the development of an international standard. Moreover, we present the special case of Spain, whose broad legislation on occupational health and safety might hinder the adoption of an international model by Spanish companies

Proceedings of the international conference on computer-aided ergonomics and safety

Centro de Informacion y Documentacion Cientifica (CINDOC). C/Joaquin Costa, 22. 28002 Madrid. SPAIN / CINDOC - Centro de Informaciòn y Documentaciòn CientìficaSIGLEESSpai