24 research outputs found
Rationality and modern society.
Recorded in Ithaca, NY by Cornell University., Sponsored by: German Literature, Department of,Women's Studies Program., Lecture, March 16, 1985.75 minutesCuller discusses Habermas' notion of communication and literary principles and his study of language in its relation to action. Mohanty serves as discussant.1_pn3hvp5
New ethnic minorities in European culture.
Recorded in Ithaca, NY by Cornell University., Sponsored by: Western Societies Program,Cornell Cinema,Council on the Creative and Performing Arts,Society for the Humanities,Arts College Dean's Fund,Near Eastern Studies, Department of., Speaker(s): Tarig Ali is a director with Banden Productions. Wanda Bershen is a programmer with CUNY T.V., New York. Anthony Caputi is a Cornell professor of Comparative Literature. Richard Herskowitz is the director of Cornell Cinema. Satya P. Mohanty is a Cornell English professor and a 1988 Society for the Humanities fellow., Panel, February 26, 1988.70 minutesThe panel discusses the British response to Sammy and Rosie Get Laid.1_qmbu87771_1a2743g
Proteomic analysis of seminal fluid from men exhibiting oxidative stress
The original publication is available at http://www.rbej.com/content/11/1/85ABSTRACT: Background: Seminal plasma serves as a natural reservoir of antioxidants. It helps to remove excessive formation of reactive oxygen species (ROS) and consequently, reduce oxidative stress. Proteomic profiling of seminal plasma proteins is important to understand the molecular mechanisms underlying oxidative stress and sperm dysfunction in infertile men.
Methods
This prospective study consisted of 52 subjects: 32 infertile men and 20 healthy donors. Once semen and oxidative stress parameters were assessed (ROS, antioxidant concentration and DNA damage), the subjects were categorized into ROS positive (ROS+) or ROS negative (ROS-). Seminal plasma from each group was pooled and subjected to proteomics analysis. In-solution digestion and protein identification with liquid chromatography tandem mass spectrometry (LC-MS/MS), followed by bioinformatics analyses was used to identify and characterize potential biomarker proteins.
Results
A total of 14 proteins were identified in this analysis with 7 of these common and unique proteins were identified in both the ROS+ and ROS- groups through MASCOT and SEQUEST analyses, respectively. Prolactin-induced protein was found to be more abundantly present in men with increased levels of ROS. Gene ontology annotations showed extracellular distribution of proteins with a major role in antioxidative activity and regulatory processes.
Conclusions
We have identified proteins that help protect against oxidative stress and are uniquely present in the seminal plasma of the ROS- men. Men exhibiting high levels of ROS in their seminal ejaculate are likely to exhibit proteins that are either downregulated or oxidatively modified, and these could potentially contribute to male infertility.Publishers' Versio
Fashioning readers: canon, criticism and pedagogy in the emergence of modern Oriya literature
Through a brief history of a widely published canon debate in nineteenth century Orissa, this article describes how anxieties about the quality of âtraditionalâ Oriya literature served as a site for imagining a cohesive Oriya public who would become the consumers and beneficiaries of a new, modernized Oriya-language canon. A public controversy about the status of Oriya literature was initiated in the 1890s with the publication of a serialized critique of the works of Upendra Bhanja, a very popular pre-colonial Oriya poet. The critic argued that Bhanjaâs writing was not true poetry, that it did not speak to the contemporary era, and that it featured embarrassingly detailed discussions of obscene material. By unpacking the terms of this criticism and Oriya responses to it, I reveal how at the heart of these discussions were concerns about community building that presupposed a new kind of readership of literature in the Oriya language. Ultimately, this article offers a longer, regional history to the emerging concern of post-colonial scholarship with relationships between publication histories, readerships, and broader ideas of community â local, Indian, and global