Optimal deployment of components of cloud-hosted application for guaranteeing multitenancy isolation

One of the challenges of deploying multitenant cloud-hosted services that are designed to use (or be integrated with) several components is how to implement the required degree of isolation between the components when there is a change in the workload. Achieving the highest degree of isolation implies deploying a component exclusively for one tenant; which leads to high resource consumption and running cost per component. A low degree of isolation allows sharing of resources which could possibly reduce cost, but with known limitations of performance and security interference. This paper presents a model-based algorithm together with four variants of a metaheuristic that can be used with it, to provide near-optimal solutions for deploying components of a cloud-hosted application in a way that guarantees multitenancy isolation. When the workload changes, the model based algorithm solves an open multiclass QN model to determine the average number of requests that can access the components and then uses a metaheuristic to provide near-optimal solutions for deploying the components. Performance evaluation showed that the obtained solutions had low variability and percent deviation when compared to the reference/optimal solution. We also provide recommendations and best practice guidelines for deploying components in a way that guarantees the required degree of isolation

Regulation of human endometrial function: mechanisms relevant to uterine bleeding

This review focuses on the complex events that occur in the endometrium after progesterone is withdrawn (or blocked) and menstrual bleeding ensues. A detailed understanding of these local mechanisms will enhance our knowledge of disturbed endometrial/uterine function – including problems with excessively heavy menstrual bleeding, endometriosis and breakthrough bleeding with progestin only contraception. The development of novel strategies to manage these clinically significant problems depends on such new understanding as does the development of new contraceptives which avoid the endometrial side effect of breakthrough bleeding

A dynamic selection of dispatching rules based on the kano model satisfaction scheduling tool

Production scheduling is a function that can contribute strongly to the competitive capacity of companies producing goods and services. Failure to stagger tasks properly causes enormous waste of time and resources, with a clear decrease in productivity and high monetary losses. The efficient use of internal resources in organizations becomes a competitive advantage and can thus dictate their survival and sustainability. In that sense, it becomes crucial to analyze and develop production scheduling models, which can be simplified as the function of affecting tasks to means of production over time. This report is part of a project to develop a dynamic scheduling tool for decision support in a single machine environment. The system created has the ability, after a first solution has been generated, to trigger a new solution as some tasks leave the system and new ones arrive, allowing the user, at each instant of time, to determine new scheduling solutions, in order to minimize a certain measure of performance. The proposed tool was validated in an in-depth computational study with dynamic task releases and stochastic execution time. The results demonstrate the effectiveness of the model.- (undefined