5 research outputs found
Reticulate evolution: frequent introgressive hybridization among chinese hares (genus lepus) revealed by analyses of multiple mitochondrial and nuclear DNA loci
<p>Abstract</p> <p>Background</p> <p>Interspecific hybridization may lead to the introgression of genes and genomes across species barriers and contribute to a reticulate evolutionary pattern and thus taxonomic uncertainties. Since several previous studies have demonstrated that introgressive hybridization has occurred among some species within <it>Lepus</it>, therefore it is possible that introgressive hybridization events also occur among Chinese <it>Lepus </it>species and contribute to the current taxonomic confusion.</p> <p>Results</p> <p>Data from four mtDNA genes, from 116 individuals, and one nuclear gene, from 119 individuals, provides the first evidence of frequent introgression events via historical and recent interspecific hybridizations among six Chinese <it>Lepus </it>species. Remarkably, the mtDNA of <it>L. mandshuricus </it>was completely replaced by mtDNA from <it>L. timidus </it>and <it>L. sinensis</it>. Analysis of the nuclear DNA sequence revealed a high proportion of heterozygous genotypes containing alleles from two divergent clades and that several haplotypes were shared among species, suggesting repeated and recent introgression. Furthermore, results from the present analyses suggest that Chinese hares belong to eight species.</p> <p>Conclusion</p> <p>This study provides a framework for understanding the patterns of speciation and the taxonomy of this clade. The existence of morphological intermediates and atypical mitochondrial gene genealogies resulting from frequent hybridization events likely contribute to the current taxonomic confusion of Chinese hares. The present study also demonstrated that nuclear gene sequence could offer a powerful complementary data set with mtDNA in tracing a complete evolutionary history of recently diverged species.</p
Syphilis depicted by the Greek moulages: a picture of skin manifestations in former times
Mitochondrial and nuclear DNA reveals reticulate evolution in hares (Lepus spp., Lagomorpha, Mammalia) from Ethiopia
Wax Anatomical Models and Neuroscience: From Artistic Italian Creation to Therapeutic Approach
Wax modelling has been used since ancient times with its first application in art in the fifteenth century involving famous artists with knowledge of anatomy. It was only in the seventeenth century that coloured ceroplastic began to be used for teaching anatomy as valid alternative to dissected human bodies, including also neuropathological. The origin of this scientific approach was born in central Italy, in Florence and Bologna in the eighteenth century, and immediately spread to other Italian cities, and Europe, and throughout the rest of the world. Wax neuro-models were shown as artefacts and destined to train young doctors in anatomical knowledge. Nowadays, wax is often considered an old-fashioned art form but what is not well known is that wax has a useful therapeutic application in medicine, with a particular emphasis in neurosurgery