Understanding of the sensitivity of East Antarctic Ice Sheet to global climatic and oceanic changes based on reconstruction/observation of the ice sheet geometry, volume, and interactions in ocean-ice-solid earth

The Tenth Symposium on Polar Science/Special session: [S] Future plan of Antarctic research: Towards phase X of the Japanese Antarctic Research Project (2022-2028) and beyond, Tue. 3 Dec. / 2F Auditorium, National Institute of Polar Researc

Glacial history of Sør Rondane Mountains in Dronning Maud Land, East Antarctica introduced by geomorphology and surface exposure ages

第3回極域科学シンポジウム　横断セッション「海・陸・氷床から探る後期新生代の南極寒冷圏環境変動」11月26日（月）、27日（火） ２階ラウン

Perspectives on the study of the Quaternary East Antarctic ice-sheet history

第2回極域科学シンポジウム　氷床コアセッション 11月16日（水） 国立極地研究所 2階大会議

Hemosuccus Pancreaticus following a Puestow Procedure in a Patient with Chronic Pancreatitis

Hemosuccus pancreaticus is an unusual cause of gastrointestinal bleeding that occurs as a complication of chronic or acute pancreatitis. We report a case of extremely acute-onset hemosuccus pancreaticus occurring in a patient with chronic pancreatitis over a long-term follow-up after a Puestow procedure (side-to-side pancreaticojejunostomy). The patient was admitted to our hospital due to severe anemia and tarry stools indicative of gastrointestinal bleeding. Emergent endoscopy, including gastrointestinal fiberscopy and colon fiberscopy, showed no abnormal findings. Abdominal contrast-enhanced computed tomography and hemorrhagic scintigraphy did not detect a hemorrhagic lesion. Although interventional radiology was considered for diagnosis and treatment, conservative therapy seemed sufficient to affect hemostasis. Two weeks later, however, acute intestinal bleeding with hemodynamic shock occurred, and exploration was performed without delay. Intraoperative endoscopy through an incision of the reconstructed jejunal loop in the close proximal end revealed a site of active bleeding from the side-to-side anastomotic pancreatic duct. Following a longitudinal incision of the jejunal loop, a bleeding point was sutured and ligated on direct inspection. The patient showed a good postoperative course

Lipid Chaperones and Metabolic Inflammation

Over the past decade, a large body of evidence has emerged demonstrating an integration of metabolic and immune response pathways. It is now clear that obesity and associated disorders such as insulin resistance and type 2 diabetes are associated with a metabolically driven, low-grade, chronic inflammatory state, referred to as “metaflammation.” Several inflammatory cytokines as well as lipids and metabolic stress pathways can activate metaflammation, which targets metabolically critical organs and tissues including adipocytes and macrophages to adversely affect systemic homeostasis. On the other hand, inside the cell, fatty acid-binding proteins (FABPs), a family of lipid chaperones, as well as endoplasmic reticulum (ER) stress, and reactive oxygen species derived from mitochondria play significant roles in promotion of metabolically triggered inflammation. Here, we discuss the molecular and cellular basis of the roles of FABPs, especially FABP4 and FABP5, in metaflammation and related diseases including obesity, diabetes, and atherosclerosis

ジテンシャコギ ウンドウジ ノ ダイタイ オヨビ カタイブ ノ oxy(Hb+Mb) ノ ヘンカ パターン ニツイテ

The purpose of this study was to measure the balance of oxygen delivery and oxygen consumption in the working muscle during the incremental cycling exercise. Using near infrared spectroscopy， we monitored the changes in oxygenated hemoglobin and myoglobin [oxy(Hb+Mb)] of the vastus lateralis muscle (VL) and lateral part of the gastrocnemius muscle (LG) during the exhaustive cycle exercise. Studies were done in healthy five male and one female volunteers while gas exchange parameters were measured. During exercise of relatively low intensity (up to 20%V02max)， oxy(Hb+Mb) increased from resting value in both VL and LG. ln VL，oxy(Hb+Mb) was sustained or decreased slowly between 40 and 50% VO2max，and decreased linearly with the exercise intensity at 50 to 80%V02max. Thereafter，it was sustained up to near 100%VO2max. In LG，on the 0ther hand， oxy(Hb+Mb) remained constant near resting levels during exercise of moderate intensity(40 to 70%V02max). During exercise of higher intensity (above 70% V02max)， there was a rapid drop. These results indicated the difference in the pattern of oxy(Hb+Mb) change between VL and LG muscles during the exhaustive incremental cycle exercise

Pressure Study of BiS2-Based Superconductors Bi4O4S3 and La(O,F)BiS2

We report the electrical resistivity measurements under pressure for the recently discovered BiS2-based layered superconductors Bi4O4S3 and La(O,F)BiS2. In Bi4O4S3, the transition temperature Tc decreases monotonically without a distinct change in the metallic behavior in the normal state. In La(O,F)BiS2, on the other hand, Tc initially increases with increasing pressure and then decreases above ? 1 GPa. The semiconducting behavior in the normal state is suppressed markedly and monotonically, whereas the evolution of Tc is nonlinear. The strong suppression of the semiconducting behavior without doping in La(O,F)BiS2 suggests that the Fermi surface is located in the vicinity of some instability. In the present study, we elucidate that the superconductivity in the BiS2 layer favors the Fermi surface at the boundary between the semiconducting and metallic behaviors.Comment: 4 pages, 6 figures, Accepted for publication in J. Phys. Soc. Jp

The recent study of the Quaternary East Antarctic ice-sheet history by Japanese Antarctic Research Expedition

第3回極域科学シンポジウム　横断セッション「海・陸・氷床から探る後期新生代の南極寒冷圏環境変動」11月27日（火） 国立国語研究所 ２階講