9,480 research outputs found
Irish republican music and (post)colonial schizophrenia
Northern Ireland remains part of the United Kingdom, yet its postcolonial position is subject to fierce debate among British loyalists and Irish republicans. Using Tommy Skellyâs 1972 âGo on Home British Soldiersâ as its central focus, this article unpicks the various (post)colonial narratives played out through republican music in the North of Ireland, challenging the parameters of the postcolonial, and demonstrating how Irish rebel songs continue to function as a form of political engagement and cultural resistance within and against the British state
Torsion and bending of nucleic acids studied by subnanosecond time-resolved fluorescence depolarization of intercalated dyes
Subnanosecond timeâresolved fluorescence depolarization has been used to monitor the reorientation of ethidium bromide intercalated in native DNA, synthetic polynucleotide complexes, and in supercoiled plasmid DNA. The fluorescence polarization anisotropy was successfully analyzed with an elastic model of DNA dynamics, including both torsion and bending, which yielded an accurate value for the torsional rigidity of the different DNA samples. The dependence of the torsional rigidity on the base sequence, helical structure, and tertiary structure was experimentally observed. The magnitude of the polyelectrolyte contribution to the torsional rigidity of DNA was measured over a wide range of ionic strength, and compared with polyelectrolyte theories for the persistence length. We also observed a rapid initial reorientation of the intercalated ethidium which had a much smaller amplitude in RNA than in DNA
Time-resolved spectroscopy of macromolecules: Effect of helical structure on the torsional dynamics of DNA and RNA
The torsional rigidity of DNA and RNA is measured via the fluorescence depolarization technique
Let The People Sing? Irish Rebel Songs, Sectarianism, and Scotlandâs Offensive Behaviour Act
Irish rebel songs afford Scotland's Irish diaspora a means to assert, experience and perform their alterity free from the complexities of the Irish language. Yet this benign intent can be offset by how the music is perceived by elements of Scotland's majority Protestant population. The Scottish Government's Offensive Behaviour Act (2012) has been used to prosecute those singing Irish rebel songs and there is continuing debate as to how this alleged offence should be dealt with. This article explores the social function and cultural perception of Irish rebel songs in the west coast of Scotland, examining what qualities lead to a song being perceived as âsectarianâ, by focusing on song lyrics, performance context and extra-musical discourse. The article explores the practice of lyrical âadd-insâ that inflect the meaning of key songs, and argues that the sectarianism of a song resides, at least in part, in the perception of the listener
Process Dissociation Analyses of Memory Changes in Healthy Aging, Preclinical, and Very Mild Alzheimer Disease: Evidence for Isolated Recollection Deficits
Recollection and familiarity are independent processes that contribute to memory performance. Recollection is dependent on attentional control, which breaks down in early-stage Alzheimer disease (AD), whereas familiarity is independent of attention. The present study examines the sensitivity of recollection estimates based on Jacobyâs (1991) process dissociation procedure to AD-related biomarkers in a large sample of well-characterized cognitively normal older adults (N = 519) and the extent to which recollection discriminates these individuals from individuals with very mild symptomatic AD (N = 64). Participants studied word pairs, e.g., âknee bone,â then completed a primed, explicit, cued fragment-completion memory task, e.g., âknee b_n_.â Primes were either congruent with the correct response, e.g., âbone,â incongruent, e.g., âbend,â or neutral, e.g., â&&&.â This design allowed for the estimation of independent contributions of recollection and familiarity processes, using the process dissociation procedure. Recollection, but not familiarity, was impaired in healthy aging and in very mild AD. Recollection discriminated cognitively normal individuals from the earliest detectable stage of symptomatic AD above and beyond standard psychometric tests. In cognitively normal individuals, baseline CSF measures indicative of AD pathology were related to lower initial recollection and less improvement in recollection over time. Finally, presence of amyloid plaques, as imaged by PIB-PET, was related to less improvement in recollection over time. These findings suggest that attention-demanding memory processes, such as recollection, may be particularly sensitive to both symptomatic and preclinical AD pathology
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