Incidence of synchronous appendiceal neoplasm in patients with colorectal cancer and its clinical significance

<p>Abstract</p> <p>Background</p> <p>The aims of this study were to evaluate the incidence of synchronous appendiceal neoplasm in patients with colorectal cancer, and to determine its clinical significance.</p> <p>Methods</p> <p>Pathological reports and medical records were reviewed of patients with colorectal adenocarcinoma who underwent oncological resection of the tumor together with appendectomy at the Faculty of Medicine Siriraj Hospital, Mahidol University, Thailand between September 2000 and April 2008.</p> <p>Results</p> <p>This study included 293 patients with an average age of 62 years (range 19–95) and 51 percent were male. Of the patients studied, 228 (78 percent) had right hemicolectomy, whereas the others (22 percent) had surgery for left-sided colon cancer or rectal cancer. One patient (0.3 percent) had epithelial appendiceal neoplasm (mucinous cystadenoma) and 3 patients (1.0 percent) had metastatic colorectal cancer in the mesoappendix. However, the presence of synchronous appendiceal tumors and/or metastasis did not alter postoperative management, as these patients had received adjuvant therapy and were scheduled for surveillance program because of nodal involvement.</p> <p>Conclusion</p> <p>The incidence of synchronous primary appendiceal neoplasm and secondary (metastatic) appendiceal neoplasm in colorectal cancer patients was 0.3 and 1.0 percent, respectively. However, these findings did not change the postoperative clinical management.</p

Dasyclad-like problematic fossils from the lower Cambrian of North Greenland

The problematic fossil Kordesphecia nyeboensis gen. et sp. nov. from the lower Cambrian of North Greenland resembles the slightly younger, putative dasycladalean alga Amgaella Korde, 1957 in terms of its spirally arranged rhombic cells and central cavity. It differs in adding new cells through the sequential addition of roofing plates ('shingles') to pre-existing cell rows rather than encrusting lateral branches in dasycladalean fashion, in which character it seems comparable to the contemporaneous Lenaella Korde, 1959) from Siberia of unknown affinity. Kordesphecia is classified as incertae sedis but may be a stem-group dasycladalean.</p