Race and Inflammatory Bowel Disease in an Urban Healthcare System

Inflammatory bowel disease (IBD) is increasingly common among non-Caucasian populations, but interracial differences in disease characteristics and management are not well-characterized. We tested the hypothesis that disease characteristics and management vary by race among IBD patients in an ethnically diverse healthcare system. A retrospective study of the safety net healthcare system of San Francisco, CA, from 1996 to 2009 was undertaken. Patient records with International Classification of Diseases, 9th Revision (ICD9) codes 555.xx, 556.xx, and 558.xx were reviewed. Adult patients with confirmed IBD diagnoses were included. Interracial variations in disease characteristics and management were assessed broadly; focused between-race comparisons identified specific differences. The 228 subjects included 77 (33.4%) with Crohn’s disease (CD), 150 (65.8%) with ulcerative colitis, and 1 (0.4%) with IBD, type unclassified. The race distribution included 105 (46.1%) white, 34 (14.9%) black, 35 (15.4%) Hispanic, and 51 (22.4%) Asian subjects. Asians and Hispanics were diagnosed at older ages (41.0 and 37.1 years, respectively) and had shorter disease durations (5.4 and 5.2 years, respectively) than whites (30.5 years at diagnosis and 8.6 years duration, P < 0.05) and blacks (31.7 years at diagnosis and 12.1 years duration, P < 0.05). CD was more common among blacks (50% of subjects) than Asians (25.5% of subjects, P = 0.015). The Montreal classification of IBD was similar among races. Hispanics were less likely than others to be treated with 5-aminosalicylates (5-ASA), immunomodulators, and steroids. Medical and surgical management was otherwise similar among races. Modest race-based differences in IBD characteristics exist in this racially diverse healthcare system, but the management of IBD is similar among race groups

TITAN'S SURFACE BRIGHTNESS TEMPERATURES

Radiance from the surface of Titan can be detected from space through a spectral window of low opacity in the thermal infrared at 19 μm (530 cm -1). By combining Composite Infrared Spectrometer observations from Cassini's first four years, we have mapped the latitude distribution of zonally averaged surface brightness temperatures. The measurements are corrected for atmospheric opacity as derived from the dependence of radiance on the emission angle. At equatorial latitudes near the Huygens landing site, the surface brightness temperature is found to be 93.7 0.6 K, in excellent agreement with the in situ measurement. Temperature decreases toward the poles, reaching 90.5 0.8 K at 87°N and 91.7 0.7 K at 88°S. The meridional distribution of temperature has a maximum near 10°S, consistent with Titan's late northern winter. © 2009 The American Astronomical Society. All rights reserved