Conformation of a Polyelectrolyte Complexed to a Like-Charged Colloid

We report results from a molecular dynamics (MD) simulation on the conformations of a long flexible polyelectrolyte complexed to a charged sphere, \textit{both negatively charged}, in the presence of neutralizing counterions in the strong Coulomb coupling regime. The structure of this complex is very sensitive to the charge density of the polyelectrolyte. For a fully charged polyelectrolyte the polymer forms a dense two-dimensional "disk", whereas for a partially charged polyelectrolyte the monomers are spread over the colloidal surface. A mechanism involving the \textit{overcharging} of the polyelectrolyte by counterions is proposed to explain the observed conformations.Comment: 4 pages, 4 figures (6 EPS files

On the age of the magnetically active WW Psa and TX Psa members of the beta Pictoris association

There are a variety of different techniques available to estimate the ages of pre-main-sequence stars. Components of physical pairs, thanks to their strict coevality and the mass difference, such as the binary system analysed in this paper, are best suited to test the effectiveness of these different techniques. We consider the system WW Psa + TX Psa whose membership of the 25-Myr beta Pictoris association has been well established by earlier works. We investigate which age dating technique provides the best agreement between the age of the system and that of the association. We have photometrically monitored WW Psa and TX Psa and measured their rotation periods as P = 2.37d and P = 1.086d, respectively. We have retrieved from the literature their Li equivalent widths and measured their effective temperatures and luminosities. We investigate whether the ages of these stars derived using three independent techniques are consistent with the age of the beta Pictoris association. We find that the rotation periods and the Li contents of both stars are consistent with the distribution of other bona fide members of the cluster. On the contrary, the isochronal fitting provides similar ages for both stars, but a factor of about four younger than the quoted age of the association, or about 30% younger when the effects of magnetic fields are included. We explore the origin of the discrepant age inferred from isochronal fitting, including the possibilities that either the two components may be unresolved binaries or that the basic stellar parameters of both components are altered by enhanced magnetic activity. The latter is found to be the more reasonable cause, suggesting that age estimates based on the Li content is more reliable than isochronal fitting for pre-main-sequence stars with pronounced magnetic activity.Comment: Accepted by Astronomy and Astrophysics on December 13, 2016. 13 pages and 11 figure

Periodontal Alteration of the Microcirculation and Hypercholesterolemia: A Possible Correlation?

OBJECTIVE: We evaluated the morphological and parametric characteristics of the periodontal microcirculation in patients diagnosed as having hypercholesterolemia and high levels of low-density lipoprotein (LDL). METHODS: Forty patients were recruited, 20 of whom were affected by hypercholesterolemia and 20 of whom were considered healthy. A videocapillaroscopic examination was carried out on the periodontal mucosa in the proximity of the frenulum (II, V sextant). RESULTS: The difference between the parameters of the hypercholesterolemia group and the control group was evaluated with the Mann-Whitney U-test for non-parametric ordinal data; the level of significance being P < 0.05. The videocapillaroscopy documented extremely significant differences between the two groups, regarding the following parameters: total diameter of the loop (P = 0.0017), diameter of the afferent loops (P = 0.0004), diameter of the efferent loops (P = 0.00008) and periodontal density (P = 0.0001). CONCLUSIONS: The capillaroscopic examination revealed a morphological alteration of the periodontal microcirculation in patients with hypercholesterolemia, which is an expression of peripheral vascular phlogosis

Human NKG2D-ligands: cell biology strategies to ensure immune recognition

Immune recognition mediated by the activating receptor NKG2D plays an important role for the elimination of stressed cells, including tumors and virus-infected cells. On the other hand, the ligands for NKG2D can also be shed into the sera of cancer patients where they weaken the immune response by downmodulating the receptor on effector cells, mainly NK and T cells. Although both families of NKG2D-ligands, major histocompatibility complex class I-related chain (MIC) A/B and UL16 binding proteins (ULBPs), are related to MHC molecules and their expression is increased after stress, many differences are observed in terms of their biochemical properties and cell trafficking. In this paper, we summarize the variety of NKG2D-ligands and propose that selection pressure has driven evolution of diversity in their trafficking and shedding, but not receptor binding affinity. However, it is also possible to identify functional properties common to individual ULBP molecules and MICA/B alleles, but not generally conserved within the MIC or ULBP families. These characteristics likely represent examples of convergent evolution for efficient immune recognition, but are also attractive targets for pathogen immune evasion strategies. Categorization of NKG2D-ligands according to their biological features, rather than their genetic family, may help to achieve a better understanding of NKG2D-ligand association with disease

How wages change: micro evidence from the International Wage Flexibility Project

How do the complex institutions involved in wage setting affect wage changes? The International Wage Flexibility Project provides new microeconomic evidence on how wages change for continuing workers. We analyze individuals’ earnings in 31 different data sets from sixteen countries, from which we obtain a total of 360 wage change distributions. We find a remarkable amount of variation in wage changes across workers. Wage changes have a notably non-normal distribution; they are tightly clustered around the median and also have many extreme values. Furthermore, nearly all countries show asymmetry in their wage distributions below the median. Indeed, we find evidence of both downward nominal and real wage rigidities. We also find that the extent of both these rigidities varies substantially across countries. Our results suggest that variations in the extent of union presence in wage bargaining play a role in explaining differing degrees of rigidities among countries. JEL Classification: E3, J3, J5Downward nominal wage rigidity, Downward real wage rigidity, Wage change distributions, Wage setting

Confined colloidal crystals in and out of equilibrium

Recent studies on confined crystals of charged colloidal particles are reviewed, both in equilibrium and out of equilibrium. We focus in particular on direct comparisons of experiments (light scattering and microscopy) with lattice sum calculations and computer simulations. In equilibrium we address buckling and crystalline multilayering of charged systems in hard and soft slit confinement. We discuss also recent crystalline structures obtained for charged mixtures. Moreover, we put forward possibilities to apply external perturbations, in order to drive the system out of equilibrium. These include electrolyte gradients as well as the application of shear and electric fields.Comment: Review article, 18 pages, 5 figure

Asymptotic Entanglement Dynamics and Geometry of Quantum States

A given dynamics for a composite quantum system can exhibit several distinct properties for the asymptotic entanglement behavior, like entanglement sudden death, asymptotic death of entanglement, sudden birth of entanglement, etc. A classification of the possible situations was given in [M. O. Terra Cunha, {\emph{New J. Phys}} {\bf{9}}, 237 (2007)] but for some classes there were no known examples. In this work we give a better classification for the possibile relaxing dynamics at the light of the geometry of their set of asymptotic states and give explicit examples for all the classes. Although the classification is completely general, in the search of examples it is sufficient to use two qubits with dynamics given by differential equations in Lindblad form (some of them non-autonomous). We also investigate, in each case, the probabilities to find each possible behavior for random initial states.Comment: 9 pages, 2 figures; revised version accepted for publication in J. Phys. A: Math. Theo

High Voltage in Noble Liquids for High Energy Physics

A workshop was held at Fermilab November 8-9, 2013 to discuss the challenges of using high voltage in noble liquids. The participants spanned the fields of neutrino, dark matter, and electric dipole moment physics. All presentations at the workshop were made in plenary sessions. This document summarizes the experiences and lessons learned from experiments in these fields at developing high voltage systems in noble liquids.Comment: 64 pages, 41 figures, 2 table