103 research outputs found

    Psychometric analysis of the perceived stress scale among healthy university students

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    © 2020 Anwer et al. Background: There is a gradual increase in the prevalence of stress during professional courses. Previous studies reported a high incidence of stress among university students. The psychometric properties of the perceived stress scale-10 (PSS-10) have been established in different populations. The current study aimed to assess psychometric properties of the PSS10 in Saudi university students. Methods: Healthy university students (n= 192) participated in this cross-sectional study. All the participants were explained about the aim and procedures of the study. Participants were requested to complete the English version of the PSS, the generalized anxiety disorder-7 (GAD-7), the sleep hygiene index (SHI), and demographic details. Results: The range of the PSS-10 total score was 0–35; 1% reported minimum score of 0, but none reported maximum score of 40. Therefore, there was no issue of ceiling or floor effect in the PSS-10 total score. Positive and significant correlations of the PSS total and the PSS Factor-1 (distress perception) with the GAD-7 total score, SHI item-8 and SHI item-13 score support its convergent validity. Negative or no correlation of the PSS Factor-2 score (coping perception) with the GAD-7 total score, SHI item-8 and SHI item-13 scores demonstrate its divergent validity. The internal homogeneity test indicated moderate to strong positive correlations (r=0.60–0.82) between the PSS Factors and the items loading on them. The internal consistency test showed a good agreement for the PSS Factor-1 and the PSS Factor-2 scores (Cronbach’s alpha 0.78 and 0.71, respectively), suggesting an acceptable level of consistency. Factor analysis favored a 2-Factor model of the PSS in the Saudi students. Conclusion: The current study supported the use of the PSS-10 to assess the perceived stress among Saudi university students

    Nurse Managers’ Competency Toward the Anticipated Turnover of Staff Nurses at Madinah City, Saudi Arabia

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    Nurses’ turnover in health institutions is a global issue, and nurse managers’ influence can be useful in providing work satisfaction, which may lessen this problem. In this article, the researcher aims to determine the skills of nurse managers that have a relationship with the anticipated turnover of staff nurses. The researcher used quantitative article utilizing three designs, descriptive-evaluative, descriptive- comparative and descriptive correlational. The article has a total of 219 respondents, of whom 69 are nurse managers, and 150 are staff nurses and used an online survey in selected hospitals in Madinah City. The researcher used weighted mean and Pearson’s r to identify the relationship between nurse managers’ skill and anticipated staff nurse turnovers. Among the results of the article, the overall answer of the nurse managers is “somewhat true.” The highest grand mean of 3.9568 was for the interpersonal skills, and the lowest was of 3.4417 for the conceptual skills. With regard to the anticipated turnover of nurses, they answered that they strongly agree that “if I got another job offer tomorrow, I would give it serious consideration” with a total mean of 3.2733. Furthermore, the interpersonal skills of nurse managers have a significant relationship with the anticipated turnover of staff nurses, as assessed by nurse managers. For the nurses’ assessment, the conceptual skills have a significant relationship with the anticipated turnover of the staff nurse. With this result, the article concluded that the staff nurse has a high possibility of leaving the organization, and among leadership skills, interpersonal skills are the strength of nurse managers, and their conceptual skills were their weakness. Health institutions should strengthen nurse managers’ skills through training and education since conceptual skills are a relevant factor of nurse managers’ competency in managing a health organization. Further paper with a larger sample is recommended. Keywords: Nurse Managers, Competency, Anticipated Turnover, Staff Nurses DOI: 10.7176/JHMN/100-05 Publication date:May 31st 202

    Potential Therapeutic Implications of Caffeic Acid in Cancer Signaling: Past, Present, and Future

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    Caffeic acid (CA) has been present in many herbs, vegetables, and fruits. CA is a bioactive compound and exhibits various health advantages that are linked with its anti-oxidant functions and implicated in the therapy and prevention of disease progression of inflammatory diseases and cancer. The anti-tumor action of CA is attributed to its prooxidant and anti-oxidant properties. CA’s mechanism of action involves preventing reactive oxygen species formation, diminishing the angiogenesis of cancer cells, enhancing the tumor cells’ DNA oxidation, and repressing MMP-2 and MMP-9. CA and its derivatives have been reported to exhibit anti-carcinogenic properties against many cancer types. CA has indicated low intestinal absorption, low oral bioavailability in rats, and pitiable permeability across Caco-2 cells. In the present review, we have illustrated CA’s therapeutic potential, pharmacokinetics, and characteristics. The pharmacological effects of CA, the emphasis on in vitro and in vivo studies, and the existing challenges and prospects of CA for cancer treatment and prevention are discussed in this review

    Pro-inflammatory markers in patients with obstructive sleep apnea and the effect of Continuous Positive Airway Pressure therapy

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    Objectives: To evaluate the association of obstructive sleep apnea (OSA) with high-sensitivity C-reactive protein (CRP) and fibrinogen levels and to assess the effect of short-term therapy using continuous positive airway pressure (CPAP). Material and Methods: A prospective, open-label, controlled trial was conducted among clinically referred patients at risk for OSA undergoing diagnostic polysomnography (PSG). After PSG, the patients were divided into 3 groups: OSA treatment group (TG) (n=21), untreated OSA group (UOG) (n=19), and non-OSA healthy control group (HCG) (n=24). CRP and fibrinogen levels were measured at baseline and one month after treatment. Repeated-measures (RM) ANOVA and ANCOVA were used to compare changes in CRP and fibrinogen levels among the three groups by analyzing between-subject and within-subject effects as functions of time and adjusting for significant covariates. Results: At baseline, OSA subjects had significantly higher CRP [t(52.37)=-2.46, p=0.02)] and fibrinogen levels [t(57)=-2.00, p=0.05)] than HCG subjects. No significant differences in CRP levels [(F(2,58)=2.29, p=0.11)] or fibrinogen levels [(F(2, 58)=1.28, p=0.29)] emerged between TG and HCG subjects after adjusting for the pretest levels. Conclusion: CPAP therapy for one month does not affect CRP and fibrinogen levels among moderate-to-severe OSA patients. However, OSA is associated with elevated levels of these inflammatory biomarkers
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