70 research outputs found
Altered Cortical Microarchitecture and Bone Metabolism in Patients with Monoclonal Gammopathy of Undetermined Significance
Patients with monoclonal gammopathy of undetermined significance (MGUS) are at increased fracture risk, and we have previously shown that MGUS patients have altered trabecular bone microarchitecture compared with controls. However, there are no data on whether the porosity of cortical bone, which may play a greater role in bone strength and the occurrence of fractures, is increased in MGUS. Thus, we studied cortical porosity and bone strength (apparent modulus) using high-resolution peripheral quantitative computed tomography imaging of the distal radius in 50 MGUS patients and 100 age-, gender-, and body mass index–matched controls. Compared with controls, MGUS patients had both significantly higher cortical porosity (+16.8%; P < .05) and lower apparent modulus (–8.9%; P < .05). Despite their larger radial bone size, MGUS patients have significantly increased cortical bone porosity and reduced bone strength relative to controls. This increased cortical porosity may explain the increased fracture risk seen in MGUS patients
Carbohydrate metabolism in floral structures of Lilium pumilum in different development stages
Determinação da energia metabolizável de diferentes alimentos testados em codornas japonesas fêmeas
Variação do teor de carboidratos em genótipos de batata armazenados em diferentes temperaturas
Waterlogging-induced changes in fermentative metabolism in roots and nodules of soybean genotypes
Qualidade textural de tomates cultivados em substratos orgânicos submetidos à aplicação de substâncias húmicas
Caracterização física, química e bioquímica do mesocarpo interno de frutos do pequizeiro colhidos em diferentes estádios de desenvolvimento
Fertilidade e reservas de carbono e nitrogênio em gemas de ramos das viníferas 'carbernet sauvignon' e 'nebbiolo'
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