8 research outputs found
Phase Transition in Sexual Reproduction and Biological Evolution
Using Monte Carlo model of biological evolution we have discovered that
populations can switch between two different strategies of their genomes'
evolution; Darwinian purifying selection and complementing the haplotypes. The
first one is exploited in the large panmictic populations while the second one
in the small highly inbred populations. The choice depends on the crossover
frequency. There is a power law relation between the critical value of
crossover frequency and the size of panmictic population. Under the constant
inbreeding this critical value of crossover does not depend on the population
size and has a character of phase transition. Close to this value sympatric
speciation is observed.Comment: 13 pages, 8 figure
Phase transition in the genome evolution favours non-random distribution of genes on chromosomes
We have used the Monte Carlo based computer models to show that selection
pressure could affect the distribution of recombination hotspots along the
chromosome. Close to critical crossover rate, where genomes may switch between
the Darwinian purifying selection or complementation of haplotypes, the
distribution of recombination events and the force of selection exerted on
genes affect the structure of chromosomes. The order of expression of gene s
and their location on chromosome may decide about the extinction or survival of
competing populations.Comment: 13 pages, 7 figures, publicatio
PHASE TRANSITION IN THE GENOME EVOLUTION FAVORS NONRANDOM DISTRIBUTION OF GENES ON CHROMOSOMES
We have used the Monte Carlo-based computer models to show that selection pressure could affect the distribution of recombination hotspots along the chromosome. Close to the critical crossover rate, where genomes may switch between the Darwinian purifying selection or complementation of haplotypes, the distribution of recombination events and the force of selection exerted on genes affect the structure of chromosomes. The order of expression of genes and their location on chromosome may decide about the extinction or survival of competing populations