Very long distance connection of gigawatt size offshore wind farms: extra high-voltage ac versus high-voltage dc cost comparison

This study presents a cost comparison between commercially available high-voltage DC (HVDC) and extra high-voltage AC shore connection (±320 kV voltage source converter and 420 kV-50 Hz single-core and three-core cables), for a 1 GW offshore wind farm cluster, considering transmission distances up to 400 km. The HVDC system is a point-to-point connection whereas multiple AC intermediate compensating stations are envisaged for AC when needed. Capital costs are evaluated from recently awarded contracts, operating costs include energy losses and missed revenues due to transmission system unavailability, both estimated using North Sea wind production curves. Optimal AC intermediate compensation, if any, and reactive profiles are also taken into account. Resultsshow that HVDC has lower transmission losses at distances in excess of 130 km; however, due to the combined effect of lower AC capital cost and unavailability, using three-core aluminium cables can be more convenient up to 360 km distance

An equivalent circuit for the evaluation of cross-country fault currents in medium voltage (MV) distribution networks

A Cross-Country Fault (CCF) is the simultaneous occurrence of a couple of Line-to-Ground Faults (LGFs), affecting different phases of same feeder or of two distinct ones, at different fault locations. CCFs are not uncommon in medium voltage (MV) public distribution networks operated with ungrounded or high-impedance neutral: despite the relatively small value of LGF current that is typical of such networks, CCF currents can be comparable to those that are found in Phase-To-Phase Faults, if the affected feeder(s) consists of cables. This occurs because the faulted cables' sheaths/screens provide a continuous, relatively low-impedance metallic return path to the fault currents. An accurate evaluation is in order, since the resulting current magnitudes can overheat sheaths/screens, endangering cable joints and other plastic sheaths. Such evaluation, however, requires the modeling of the whole MV network in the phase domain, simulating cable screens and their connections to the primary and secondary substation earth electrodes by suitable computer programs, such as ATP (which is the acronym for alternative transient program) or EMTP (the acronym for electromagnetic transient program), with substantial input data being involved. This paper presents a simplified yet accurate circuit model of the faulted MV network, taking into account the CCF currents' return path (cable sheaths/screens, ground conductors, and earthing resistances of secondary substations). The proposed CCF model can be implemented in a general-purpose simulation program, and it yields accurate fault currents estimates: for a 20 kV network case study, the comparison with accurate ATP simulations evidences mismatches mostly smaller than 2%, and never exceeding 5%

Monte Carlo evaluation of the impact of subsequent strokes on backflashover rate

The paper deals with the impact of subsequent strokes on the backflashover rate (BFR) of HV overhead transmission lines (OHLs), assessed by means of an ATP-EMTP Monte Carlo procedure. The application to a typical 150 kV Italian OHL is discussed, simulating several tower grounding system arrangements. Subsequent strokes parameters are added to the statistical simulation variables: Peak current, front time, time-to-half value, lightning polarity, line insulation withstand, lightning location and phase angle of the power frequency voltage. The input data are fed to an ATP-EMTP complete circuit model of the OHL, including line insulation, lightning representation and tower grounding system, the latter simulated by a pi-circuit model able to simulate the effects due to propagation and soil ionization, at modest computational costs. Numerical results evidence a non-negligible BFR increase (in relative terms) due to subsequent strokes: for spatially concentrated grounding systems the BFR increase approximatively vary in inverse proportion with the low frequency grounding resistance, whereas for spatially extended grounding systems the BFR increase depends on the grounding system behavior at high frequencies

Tower grounding improvement versus line surge arresters: comparison of remedial measures for high-BFOR subtransmission lines

This paper presents a technical/economic comparison between remedial measures aimed at improving the lightning performance of an existing Italian three-phase 150-kV overhead line. The line is characterized by a very high back-flashover rate (BFOR), due to large grounding resistance values. Two countermeasures are proposed: grounding system improvement with additional vertical rods and line metal oxide surge arrester (MOSA) installation on one or all phases. A Monte Carlo ATP-EMTP procedure developed by the authors, which takes into account both the tower grounding nonlinear transient response due to soil ionization and MOSA nonlinear response, has been applied to evaluate and compare the effectiveness of the proposed countermeasures. The installation of MOSA on all phases is technically the best option, but it is relatively expensive. Tower grounding improvement and MOSA installation on the lower phase yield very similar BFORs: the economic comparison strongly depends on tower's accessibility and soil nature

Rotational sensitivity of the "G-Pisa" gyrolaser

G-Pisa is an experiment investigating the possibility to operate a high sensitivity laser gyroscope with area less than $1 \rm m^2$ for improving the performances of the mirrors suspensions of the gravitational wave antenna Virgo. The experimental set-up consists in a He-Ne ring laser with a 4 mirrors square cavity. The laser is pumped by an RF discharge where the RF oscillator includes the laser plasma in order to reach a better stability. The contrast of the Sagnac fringes is typically above 50% and a stable regime has been reached with the laser operating both single mode or multimode. The effect of hydrogen contamination on the laser was also checked. A low-frequency sensitivity, below $1 \rm Hz$, in the range of $10^{-8} \rm {(rad / s)/ \sqrt{Hz}}$ has been measured.Comment: 6 pages, 6 figures, presented at the EFTF-IFCS joint conference 200

False Data Injection Impact on High RES Power Systems with Centralized Voltage Regulation Architecture

The increasing penetration of distributed generation (DG) across power distribution networks (DNs) is forcing distribution system operators (DSOs) to improve the voltage regulation capabilities of the system. The increase in power flows due to the installation of renewable plants in unexpected zones of the distribution grid can affect the voltage profile, even causing interruptions at the secondary substations (SSs) with the voltage limit violation. At the same time, widespread cyberattacks across critical infrastructure raise new challenges in security and reliability for DSOs. This paper analyzes the impact of false data injection related to residential and non-residential customers on a centralized voltage regulation system, in which the DG is required to adapt the reactive power exchange with the grid according to the voltage profile. The centralized system estimates the distribution grid state according to the field data and provides the DG plants with a reactive power request to avoid voltage violations. A preliminary false data analysis in the context of the energy sector is carried out to build up a false data generator algorithm. Afterward, a configurable false data generator is developed and exploited. The false data injection is tested in the IEEE 118-bus system with an increasing DG penetration. The false data injection impact analysis highlights the need to increase the security framework of DSOs to avoid facing a relevant number of electricity interruptions

CDX-2 expression correlates with clinical outcomes in MSI-H metastatic colorectal cancer patients receiving immune checkpoint inhibitors

Immune checkpoint inhibitors (ICIs) showed efficacy in metastatic colorectal cancer (mCRC) with mismatch-repair deficiency or high microsatellite instability (dMMR-MSI-H). Unfortunately, a patient's subgroup did not benefit from immunotherapy. Caudal-related homeobox transcription factor 2 (CDX-2) would seem to influence immunotherapy's sensitivity, promoting the chemokine (C-X-C motif) ligand 14 (CXCL14) expression. Therefore, we investigated CDX-2 role as a prognostic-predictive marker in patients with mCRC MSI-H. We retrospectively collected data from 14 MSI-H mCRC patients treated with ICIs between 2019 and 2021. The primary endpoint was the 12-month progression-free-survival (PFS) rate. The secondary endpoints were overall survival (OS), PFS, objective response rate (ORR), and disease control rate (DCR). The PFS rate at 12 months was 81% in CDX-2 positive patients vs 0% in CDX-2 negative patients (p = 0.0011). The median PFS was not reached (NR) in the CDX-2 positive group versus 2.07 months (95%CI 2.07-10.8) in CDX-2 negative patients (p = 0.0011). Median OS was NR in CDX-2-positive patients versus 2.17 months (95% Confidence Interval [CI] 2.17-18.7) in CDX2-negative patients (p = 0.026). All CDX-2-positive patients achieved a disease response, one of them a complete response. Among CDX-2-negative patients, one achieved stable disease, while the other progressed rapidly (ORR: 100% vs 0%, p = 0.0005; DCR: 100% vs 50%, p = 0.02). Twelve patients received 1st-line pembrolizumab (11 CDX-2 positive and 1 CDX-2 negative) not reaching median PFS, while two patients (1 CDX-2 positive and 1 CDX-2 negative) received 3rd-line pembrolizumab reaching a median PFS of 10.8 months (95% CI, 10.8-12.1; p = 0.036). Although our study reports results on a small population, the prognostic role of CDX-2 in CRC seems confirmed and could drive a promising predictive role in defining the population more sensitive to immunotherapy treatment. Modulating the CDX-2/CXCL14 axis in CDX-2-negative patients could help overcome primary resistance to immunotherapy

Notulae to the Italian alien vascular flora: 17

In this contribution, new data concerning the distribution of vascular flora alien to Italy are presented. It includes new records and status changes from casual to naturalized for Italy or for Italian administrative regions for taxa in the genera Callianthe, Chamaecyparis, Chamaeiris, Cotoneaster, Erigeron, Freesia, Hemerocallis, Juglans, Kalanchoë, Ludwigia, Nassella, Paulownia, Physocarpus, Pistia, Saccharum, Setaria, and Vachellia. Nomenclatural and distribution updates, published elsewhere, and corrections are provided as supplementary material

GINGER

In this paper, we outline the scientific objectives, the experimental layout, and the collaborations envisaged for the GINGER (Gyroscopes IN GEneral Relativity) project. The GINGER project brings together different scientific disciplines aiming at building an array of Ring Laser Gyroscopes (RLGs), exploiting the Sagnac effect, to measure continuously, with sensitivity better than picorad/ s, large bandwidth (ca. 1 kHz), and high dynamic range, the absolute angular rotation rate of the Earth. In the paper, we address the feasibility of the apparatus with respect to the ambitious specifications above, as well as prove how such an apparatus, which will be able to detect strong Earthquakes, very weak geodetic signals, as well as general relativity effects like Lense-Thirring and De Sitter, will help scientific advancements in Theoretical Physics, Geophysics, and Geodesy, among other scientific fields.Comment: 21 pages, 9 figure