1,609 research outputs found

    ‘Other spaces’ for lesbian, gay, bisexual, transgendered and questioning (LGBTQ) students: positioning LGBTQ-affirming schools as sites of resistance within inclusive education

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    This article explores the growing interest in schools which are aimed at children and young people who are lesbian, gay, bisexual, transgendered and questioning (LGBTQ), schools described as LGBTQ-affirming. Schools which target specific groups of students are sometimes viewed as being anti-inclusive because they assign labels to students and separate them from one another. This is based on a notion of inclusive education as a single ‘school for all’; a comprehensive, common school which is suitable for all children in a particular locality. Using academic literature alongside original data from an in-depth qualitative case study of an LGBTQ-affirming school in Atlanta, this article addresses the question of whether there is a place for LGBTQ-affirming schools within inclusive education systems. It argues that the word ‘segregated’ is not an accurate description of these schools, positing that segregated spaces are not the same as separate spaces. It argues that the separateness of LGBTQ-affirming schools is important to their role in inclusive education, specifically when they are positioned as examples of Foucault’s heterotopias. Viewing them through this theoretical lens enables them to be seen as ‘other spaces’, as a form of ‘resistance’ and ‘protest’ which may ‘unstitch’ the utopian vision of inclusive education

    Aging Effects of Caenorhabditis elegans Ryanodine Receptor Variants Corresponding to Human Myopathic Mutations

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    Delaying the decline in skeletal muscle function will be critical to better maintenance of an active life-style in old age. The skeletal muscle ryanodine receptor, the major intracellular membrane channel through which calcium ions pass to elicit muscle contraction, is central to calcium ion balance, and is hypothesized to be a significant factor for age-related decline in muscle function. The nematode Caenorhabditis elegans is a key model system for the study of human aging and strains with modified C. elegans ryanodine receptors corresponding to human myopathic variants linked with malignant hyperthermia and related conditions were generated. The altered response of these strains to pharmacological agents reflected results of human diagnostic tests for individuals with these pathogenic variants. Involvement of nerve cells in the C. elegans responses may relate to rare medical symptoms concerning the central nervous system that have been associated with ryanodine receptor variants. These single amino acid modifications in C. elegans also conferred a reduction in lifespan and an accelerated decline in muscle integrity with age, supporting the significance of ryanodine receptor function for human aging

    The effect of mode and context on survey results: Analysis of data from the Health Survey for England 2006 and the Boost Survey for London

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    Background: Health-related data at local level could be provided by supplementing national health surveys with local boosts. Self-completion surveys are less costly than interviews, enabling larger samples to be achieved for a given cost. However, even when the same questions are asked with the same wording, responses to survey questions may vary by mode of data collection. These measurement differences need to be investigated further.Methods: The Health Survey for England in London ('Core') and a London Boost survey ('Boost') used identical sampling strategies but different modes of data collection. Some data were collected by face-to-face interview in the Core and by self-completion in the Boost; other data were collected by self-completion questionnaire in both, but the context differed.Results were compared by mode of data collection using two approaches. The first examined differences in results that remained after adjusting the samples for differences in response. The second compared results after using propensity score matching to reduce any differences in sample composition. Results: There were no significant differences between the two samples for prevalence of some variables including long-term illness, limiting long-term illness, current rates of smoking, whether participants drank alcohol, and how often they usually drank. However, there were a number of differences, some quite large, between some key measures including: general health, GHQ12 score, portions of fruit and vegetables consumed, levels of physical activity, and, to a lesser extent, smoking consumption, the number of alcohol units reported consumed on the heaviest day of drinking in the last week and perceived social support (among women only).Conclusion: Survey mode and context can both affect the responses given. The effect is largest for complex question modules but was also seen for identical self-completion questions. Some data collected by interview and self-completion can be safely combined

    The effect of survey method on survey participation: Analysis of data from the Health Survey for England 2006 and the Boost Survey for London

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    Background: There is a need for local level health data for local government and health bodies, for health surveillance and planning and monitoring of policies and interventions. The Health Survey for England (HSE) is a nationally-representative survey of the English population living in private households, but sub-national analyses can be performed only at a regional level because of sample size. A boost of the HSE was commissioned to address the need for local level data in London but a different mode of data collection was used to maximise participant numbers for a given cost. This study examines the effects on survey and item response of the different survey modes.Methods: Household and individual level data are collected in HSE primarily through interviews plus individual measures through a nurse visit. For the London Boost, brief household level data were collected through interviews and individual level data through a longer self-completion questionnaire left by the interviewer and collected later. Sampling and recruitment methods were identical, and both surveys were conducted by the same organisation. There was no nurse visit in the London Boost. Data were analysed to assess the effects of differential response rates, item non-response, and characteristics of respondents.Results: Household response rates were higher in the 'Boost' (61%) than 'Core' (HSE participants in London) sample (58%), but the individual response rate was considerably higher in the Core (85%) than Boost (65%). There were few differences in participant characteristics between the Core and Boost samples, with the exception of ethnicity and educational qualifications. Item non-response was similar for both samples, except for educational level. Differences in ethnicity were corrected with non-response weights, but differences in educational qualifications persisted after non-response weights were applied. When item non-response was added to those reporting no qualification, participants' educational levels were similar in the two samples.Conclusion: Although household response rates were similar, individual response rates were lower using the London Boost method. This may be due to features of London that are particularly associated with lower response rates for the self-completion element of the Boost method, such as the multi-lingual population. Nevertheless, statistical adjustments can overcome most of the demographic differences for analysis. Care must be taken when designing self-completion questionnaires to minimise item non-response

    Revealing the Structure and Oxygen Transport at Interfaces in Complex Oxide Heterostructures via Âč⁷O NMR Spectroscopy

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    Vertically aligned nanocomposite (VAN) films, comprising nanopillars of one phase embedded in a matrix of another, have shown great promise for a range of applications due to their high interfacial areas oriented perpendicular to the substrate. In particular, oxide VANs show enhanced oxide-ion conductivity in directions that are orthogonal to those found in more conventional thin-film heterostructures; however, the structure of the interfaces and its influence on conductivity remain unclear. In this work, 17O NMR spectroscopy is used to study CeO2–SrTiO3 VAN thin films: selective isotopic enrichment is combined with a lift-off technique to remove the substrate, facilitating detection of the 17O NMR signal from single atomic layer interfaces. By performing the isotopic enrichment at variable temperatures, the superior oxide-ion conductivity of the VAN films compared to the bulk materials is shown to arise from enhanced oxygen mobility at this interface; oxygen motion at the interface is further identified from 17O relaxometry experiments. The structure of this interface is solved by calculating the NMR parameters using density functional theory combined with random structure searching, allowing the chemistry underpinning the enhanced oxide-ion transport to be proposed. Finally, a comparison is made with 1% Gd-doped CeO2–SrTiO3 VAN films, for which greater NMR signal can be obtained due to paramagnetic relaxation enhancement, while the relative oxide-ion conductivities of the phases remain similar. These results highlight the information that can be obtained on interfacial structure and dynamics with solid-state NMR spectroscopy, in this and other nanostructured systems, our methodology being generally applicable to overcome sensitivity limitations in thin-film studies

    Cross‐cultural differences in eyewitness memory reports

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    Increasingly, investigators conduct interviews with eyewitnesses from different cultures. The culture in which people have been socialised can impact the way they encode, remember, and report information about their experiences. We examined whether eyewitness memory reports of mock witnesses from collectivistic (sub-Saharan Africa) and individualistic (Northern Europe) cultures differed regarding quantity and quality of central and background details reported. Mock witnesses (total N = 200) from rural Ghana, urban Ghana, and the Netherlands were shown stimuli scenes of crimes in Dutch and Ghanaian settings and provided free and cued recalls. Individualistic culture mock witnesses reported the most details, irrespective of detail type. For each cultural group, mock witnesses reported more correct central details when crime was witnessed in their own native setting than a non-native setting, though for different recall domains. The findings provide insight for legal and investigative professionals as well as immigration officials eliciting memory reports in cross-cultural contexts

    Dynamics and Stability of an Optically Levitated Mirror

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    We analyse the dynamics of a one-dimensional vertical Fabry-P\'erot cavity, where the upper mirror levitates due to intra-cavity radiation pressure force. A perturbative approach is used based around separation of timescales, which allows us to calculate the physical quantities of interest. Due to the dynamics of the cavity field, we find that the upper mirror's motion will always be unstable for levitation performed using only a single laser. Stability can be achieved for two lasers, where one provides the trapping potential and the other a damping effect, and we locate and characterise all parameter regimes where this can occur. Finally we analyse photothermal effects due to heating of the mirror substrate. We show that this can stabilise the system, even with only a single input laser, if it acts to increase the optical path length of the cavity. This work serves as a foundation for understanding how levitated optical cavity schemes can be used as stable metrological platforms.Comment: 14 pages, 7 figures. Code & data available for download at github.com/ruvilecamwasam/lmdynamic
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